570 research outputs found
Selective expression of RT6 superfamily in human bronchial epithelial cells.
RT6 proteins are glycosylphosphatidylinositol (GPI)-linked alloantigens that are localized to cytotoxic T lymphocytes and that have nicotinamide adenine dinucleotide glycohydrolase and adenosine diphosphate (ADP)-ribosyltransferase activities. In view of the importance of GPI-linked surface proteins in mediating interactions of cells with their milieu, and the varied functions of airway cells in inflammation, we undertook the present study to determine whether human homologues of the RT6 superfamily of ADP-ribosyltransferases (ART) are expressed in pulmonary epithelial cells. We hypothesized that these surface proteins or related family members may be present in cells that interact with inflammatory cells, and that they may thereby be involved in intercellular signaling. Using in situ analysis and Northern blot analysis, we identified ART1 messenger RNA (mRNA) in airway epithelial cells. As expected for GPI-anchored proteins, the localization of ART1 at the apical surface of ciliated epithelial cells was demonstrated by staining with polyclonal anti-ART1 antibody, and was confirmed by loss of this immunoreactivity after treatment with phosphatidylinositol-specific phospholipase C (PI-PLC), which selectively cleaves GPI anchors and releases proteins from the plasma membrane. Using in situ hybridization with specific ART3 and ART4 oligonucleotides, we also identified two additional members of the RT6 superfamily in epithelial cells. In accord with these findings, we identified ART3 and ART4 mRNAs through reverse transcription- polymerase chain reaction of polyadenine-positive RNA from human trachea. Interestingly, these proteins appeared to be preferentially localized to the airway epithelium. The localized expression of these members of the RT6 superfamily in human pulmonary epithelial cells may reflect a role for them in cell-cell signaling during immune responses within the airwa
Electrical Conductivity of Fermi Liquids. I. Many-body Effect on the Drude Weight
On the basis of the Fermi liquid theory, we investigate the many-body effect
on the Drude weight. In a lattice system, the Drude weight is modified by
electron-electron interaction due to Umklapp processes, while it is not
renormalized in a Galilean invariant system. This is explained by showing that
the effective mass for is defined through the current, not
velocity, of quasiparticle. It is shown that the inequality is required
for the stability against the uniform shift of the Fermi surface. The result of
perturbation theory applied for the Hubbard model indicates that as a
function of the density is qualitatively modified around half filling
by Umklapp processes.Comment: 20 pages, 2 figures; J. Phys. Soc. Jpn. Vol.67, No.
Curve crossing in linear potential grids: the quasidegeneracy approximation
The quasidegeneracy approximation [V. A. Yurovsky, A. Ben-Reuven, P. S.
Julienne, and Y. B. Band, J. Phys. B {\bf 32}, 1845 (1999)] is used here to
evaluate transition amplitudes for the problem of curve crossing in linear
potential grids involving two sets of parallel potentials. The approximation
describes phenomena, such as counterintuitive transitions and saturation
(incomplete population transfer), not predictable by the assumption of
independent crossings. Also, a new kind of oscillations due to quantum
interference (different from the well-known St\"uckelberg oscillations) is
disclosed, and its nature discussed. The approximation can find applications in
many fields of physics, where multistate curve crossing problems occur.Comment: LaTeX, 8 pages, 8 PostScript figures, uses REVTeX and psfig,
submitted to Physical Review
Consistency tests of AMPCALCULATOR and chiral amplitudes in SU(3) Chiral Perturbation Theory: A tutorial based approach
Ampcalculator is a Mathematica based program that was made publicly available
some time ago by Unterdorfer and Ecker. It enables the user to compute several
processes at one-loop (upto ) in SU(3) chiral perturbation theory. They
include computing matrix elements and form factors for strong and non-leptonic
weak processes with at most six external states. It was used to compute some
novel processes and was tested against well-known results by the original
authors. Here we present the results of several thorough checks of the package.
Exhaustive checks performed by the original authors are not publicly available,
and hence the present effort. Some new results are obtained from the software
especially in the kaon odd-intrinsic parity non-leptonic decay sector involving
the coupling . Another illustrative set of amplitudes at tree level we
provide is in the context of -decays with several mesons including quark
mass effects, of use to the BELLE experiment. All eight meson-meson scattering
amplitudes have been checked. Kaon-Compton amplitude has been checked and a
minor error in published results has been pointed out. This exercise is a
tutorial based one, wherein several input and output notebooks are also being
made available as ancillary files on the arXiv. Some of the additional
notebooks we provide contain explicit expressions that we have used for
comparison with established results. The purpose is to encourage users to apply
the software to suit their specific needs. An automatic amplitude generator of
this type can provide error-free outputs that could be used as inputs for
further simplification, and used in varied scenarios such as applications of
chiral perturbation theory at finite temperature, density and volume. This can
also be used by students as a learning aid in low-energy hadron dynamics.Comment: 25 pages, plain latex, corresponds to version to appear in EPJA,
additional ancillary files adde
Insulator-Metal Transition in the One and Two-Dimensional Hubbard Models
We use Quantum Monte Carlo methods to determine Green functions,
, on lattices up to for the 2D Hubbard model
at . For chemical potentials, , within the Hubbard gap, , and at {\it long} distances, , with critical behavior: , . This result stands in agreement with the
assumption of hyperscaling with correlation exponent and dynamical
exponent . In contrast, the generic band insulator as well as the
metal-insulator transition in the 1D Hubbard model are characterized by and .Comment: 9 pages (latex) and 5 postscript figures. Submitted for publication
in Phys. Rev. Let
Specific Heat of the 2D Hubbard Model
Quantum Monte Carlo results for the specific heat c of the two dimensional
Hubbard model are presented. At half-filling it was observed that
at very low temperatures. Two distinct features were also identified: a low
temperature peak related to the spin degrees of freedom and a higher
temperature broad peak related to the charge degrees of freedom. Away from
half-filling the spin induced feature slowly disappears as a function of hole
doping while the charge feature moves to lower temperature. A comparison with
experimental results for the high temperature cuprates is discussed.Comment: 6 pages, RevTex, 11 figures embedded in the text, Submitted to Phys.
Rev.
Perturbation study on the spin and charge susceptibilities of the two-dimensional Hubbard model
We investigate the spin and charge susceptibilities of the two-dimensional
Hubbard model based upon the perturbative calculation in the strength of
correlation . For comparable to a bare bandwidth, the charge
susceptibility decreases near the half-filling as hole-doping approaches zero.
This behavior suggesting the precursor of the Mott-Hubbard gap formation cannot
be obtained without the vertex corrections beyond the random phase
approximation. In the low-temperature region, the spin susceptibility deviates
from the Curie-Weiss-like law and finally turns to decrease with the decrease
of temperature. This spin-gap-like behavior is originating from the van Hove
singularity in the density of states.Comment: Revtex file + 11 figures, to appear in Phys. Rev.
Cyclization of a carbon-centered radical derived from oxaziridine cleavage
Treatment of an oxaziridine with low-valent iron or copper salts generates a carbon-centered radical able to cyclize onto an appended olefin
Thermodynamics of doped Kondo insulator in one dimension: Finite Temperature DMRG Study
The finite-temperature density-matrix renormalization-group method is applied
to the one-dimensional Kondo lattice model near half filling to study its
thermodynamics. The spin and charge susceptibilities and entropy are calculated
down to T=0.03t. We find two crossover temperatures near half filling. The
higher crossover temperature continuously connects to the spin gap at half
filling, and the susceptibilities are suppressed around this temperature. At
low temperatures, the susceptibilities increase again with decreasing
temperature when doping is finite. We confirm that they finally approach to the
values obtained in the Tomonaga-Luttinger (TL) liquid ground state for several
parameters. The crossover temperature to the TL liquid is a new energy scale
determined by gapless excitations of the TL liquid. The transition from the
metallic phase to the insulating phase is accompanied by the vanishing of the
lower crossover temperature.Comment: 4 pages, 7 Postscript figures, REVTe
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