570 research outputs found

    Selective expression of RT6 superfamily in human bronchial epithelial cells.

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    RT6 proteins are glycosylphosphatidylinositol (GPI)-linked alloantigens that are localized to cytotoxic T lymphocytes and that have nicotinamide adenine dinucleotide glycohydrolase and adenosine diphosphate (ADP)-ribosyltransferase activities. In view of the importance of GPI-linked surface proteins in mediating interactions of cells with their milieu, and the varied functions of airway cells in inflammation, we undertook the present study to determine whether human homologues of the RT6 superfamily of ADP-ribosyltransferases (ART) are expressed in pulmonary epithelial cells. We hypothesized that these surface proteins or related family members may be present in cells that interact with inflammatory cells, and that they may thereby be involved in intercellular signaling. Using in situ analysis and Northern blot analysis, we identified ART1 messenger RNA (mRNA) in airway epithelial cells. As expected for GPI-anchored proteins, the localization of ART1 at the apical surface of ciliated epithelial cells was demonstrated by staining with polyclonal anti-ART1 antibody, and was confirmed by loss of this immunoreactivity after treatment with phosphatidylinositol-specific phospholipase C (PI-PLC), which selectively cleaves GPI anchors and releases proteins from the plasma membrane. Using in situ hybridization with specific ART3 and ART4 oligonucleotides, we also identified two additional members of the RT6 superfamily in epithelial cells. In accord with these findings, we identified ART3 and ART4 mRNAs through reverse transcription- polymerase chain reaction of polyadenine-positive RNA from human trachea. Interestingly, these proteins appeared to be preferentially localized to the airway epithelium. The localized expression of these members of the RT6 superfamily in human pulmonary epithelial cells may reflect a role for them in cell-cell signaling during immune responses within the airwa

    Electrical Conductivity of Fermi Liquids. I. Many-body Effect on the Drude Weight

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    On the basis of the Fermi liquid theory, we investigate the many-body effect on the Drude weight. In a lattice system, the Drude weight DD is modified by electron-electron interaction due to Umklapp processes, while it is not renormalized in a Galilean invariant system. This is explained by showing that the effective mass mm' for Dn/mD\propto n/m' is defined through the current, not velocity, of quasiparticle. It is shown that the inequality D>0D>0 is required for the stability against the uniform shift of the Fermi surface. The result of perturbation theory applied for the Hubbard model indicates that DD as a function of the density nn is qualitatively modified around half filling n1n\sim 1 by Umklapp processes.Comment: 20 pages, 2 figures; J. Phys. Soc. Jpn. Vol.67, No.

    Curve crossing in linear potential grids: the quasidegeneracy approximation

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    The quasidegeneracy approximation [V. A. Yurovsky, A. Ben-Reuven, P. S. Julienne, and Y. B. Band, J. Phys. B {\bf 32}, 1845 (1999)] is used here to evaluate transition amplitudes for the problem of curve crossing in linear potential grids involving two sets of parallel potentials. The approximation describes phenomena, such as counterintuitive transitions and saturation (incomplete population transfer), not predictable by the assumption of independent crossings. Also, a new kind of oscillations due to quantum interference (different from the well-known St\"uckelberg oscillations) is disclosed, and its nature discussed. The approximation can find applications in many fields of physics, where multistate curve crossing problems occur.Comment: LaTeX, 8 pages, 8 PostScript figures, uses REVTeX and psfig, submitted to Physical Review

    Consistency tests of AMPCALCULATOR and chiral amplitudes in SU(3) Chiral Perturbation Theory: A tutorial based approach

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    Ampcalculator is a Mathematica based program that was made publicly available some time ago by Unterdorfer and Ecker. It enables the user to compute several processes at one-loop (upto O(p4)O(p^4)) in SU(3) chiral perturbation theory. They include computing matrix elements and form factors for strong and non-leptonic weak processes with at most six external states. It was used to compute some novel processes and was tested against well-known results by the original authors. Here we present the results of several thorough checks of the package. Exhaustive checks performed by the original authors are not publicly available, and hence the present effort. Some new results are obtained from the software especially in the kaon odd-intrinsic parity non-leptonic decay sector involving the coupling G27G_{27}. Another illustrative set of amplitudes at tree level we provide is in the context of τ\tau-decays with several mesons including quark mass effects, of use to the BELLE experiment. All eight meson-meson scattering amplitudes have been checked. Kaon-Compton amplitude has been checked and a minor error in published results has been pointed out. This exercise is a tutorial based one, wherein several input and output notebooks are also being made available as ancillary files on the arXiv. Some of the additional notebooks we provide contain explicit expressions that we have used for comparison with established results. The purpose is to encourage users to apply the software to suit their specific needs. An automatic amplitude generator of this type can provide error-free outputs that could be used as inputs for further simplification, and used in varied scenarios such as applications of chiral perturbation theory at finite temperature, density and volume. This can also be used by students as a learning aid in low-energy hadron dynamics.Comment: 25 pages, plain latex, corresponds to version to appear in EPJA, additional ancillary files adde

    Insulator-Metal Transition in the One and Two-Dimensional Hubbard Models

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    We use Quantum Monte Carlo methods to determine T=0T=0 Green functions, G(r,ω)G(\vec{r}, \omega), on lattices up to 16×1616 \times 16 for the 2D Hubbard model at U/t=4U/t =4. For chemical potentials, μ\mu, within the Hubbard gap, μ<μc |\mu | < \mu_c, and at {\it long} distances, r\vec{r}, G(r,ω=μ)er/ξlG(\vec{r}, \omega = \mu) \sim e^{ -|\vec{r}|/\xi_l} with critical behavior: ξlμμcν\xi_l \sim | \mu - \mu_c |^{-\nu}, ν=0.26±0.05 \nu = 0.26 \pm 0.05. This result stands in agreement with the assumption of hyperscaling with correlation exponent ν=1/4\nu = 1/4 and dynamical exponent z=4z = 4. In contrast, the generic band insulator as well as the metal-insulator transition in the 1D Hubbard model are characterized by ν=1/2\nu = 1/2 and z=2z = 2.Comment: 9 pages (latex) and 5 postscript figures. Submitted for publication in Phys. Rev. Let

    Specific Heat of the 2D Hubbard Model

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    Quantum Monte Carlo results for the specific heat c of the two dimensional Hubbard model are presented. At half-filling it was observed that cT2c \sim T^2 at very low temperatures. Two distinct features were also identified: a low temperature peak related to the spin degrees of freedom and a higher temperature broad peak related to the charge degrees of freedom. Away from half-filling the spin induced feature slowly disappears as a function of hole doping while the charge feature moves to lower temperature. A comparison with experimental results for the high temperature cuprates is discussed.Comment: 6 pages, RevTex, 11 figures embedded in the text, Submitted to Phys. Rev.

    Perturbation study on the spin and charge susceptibilities of the two-dimensional Hubbard model

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    We investigate the spin and charge susceptibilities of the two-dimensional Hubbard model based upon the perturbative calculation in the strength of correlation UU. For UU comparable to a bare bandwidth, the charge susceptibility decreases near the half-filling as hole-doping approaches zero. This behavior suggesting the precursor of the Mott-Hubbard gap formation cannot be obtained without the vertex corrections beyond the random phase approximation. In the low-temperature region, the spin susceptibility deviates from the Curie-Weiss-like law and finally turns to decrease with the decrease of temperature. This spin-gap-like behavior is originating from the van Hove singularity in the density of states.Comment: Revtex file + 11 figures, to appear in Phys. Rev.

    Cyclization of a carbon-centered radical derived from oxaziridine cleavage

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    Treatment of an oxaziridine with low-valent iron or copper salts generates a carbon-centered radical able to cyclize onto an appended olefin

    Thermodynamics of doped Kondo insulator in one dimension: Finite Temperature DMRG Study

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    The finite-temperature density-matrix renormalization-group method is applied to the one-dimensional Kondo lattice model near half filling to study its thermodynamics. The spin and charge susceptibilities and entropy are calculated down to T=0.03t. We find two crossover temperatures near half filling. The higher crossover temperature continuously connects to the spin gap at half filling, and the susceptibilities are suppressed around this temperature. At low temperatures, the susceptibilities increase again with decreasing temperature when doping is finite. We confirm that they finally approach to the values obtained in the Tomonaga-Luttinger (TL) liquid ground state for several parameters. The crossover temperature to the TL liquid is a new energy scale determined by gapless excitations of the TL liquid. The transition from the metallic phase to the insulating phase is accompanied by the vanishing of the lower crossover temperature.Comment: 4 pages, 7 Postscript figures, REVTe
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