Hepatotoxic Effects of Sera from Patients with Fulminant Hepatitis B on Isolated Rat Hepatocytes in Culture

Peer Reviewe

Using Microsatellites to Understand the Physical Distribution of Recombination on Soybean Chromosomes

Soybean is a major crop that is an important source of oil and proteins. A number of genetic linkage maps have been developed in soybean. Specifically, hundreds of simple sequence repeat (SSR) markers have been developed and mapped. Recent sequencing of the soybean genome resulted in the generation of vast amounts of genetic information. The objectives of this investigation were to use SSR markers in developing a connection between genetic and physical maps and to determine the physical distribution of recombination on soybean chromosomes. A total of 2,188 SSRs were used for sequence-based physical localization on soybean chromosomes. Linkage information was used from different maps to create an integrated genetic map. Comparison of the integrated genetic linkage maps and sequence based physical maps revealed that the distal 25% of each chromosome was the most marker-dense, containing an average of 47.4% of the SSR markers and 50.2% of the genes. The proximal 25% of each chromosome contained only 7.4% of the markers and 6.7% of the genes. At the whole genome level, the marker density and gene density showed a high correlation (R2) of 0.64 and 0.83, respectively with the physical distance from the centromere. Recombination followed a similar pattern with comparisons indicating that recombination is high in telomeric regions, though the correlation between crossover frequency and distance from the centromeres is low (R2 = 0.21). Most of the centromeric regions were low in recombination. The crossover frequency for the entire soybean genome was 7.2%, with extremes much higher and lower than average. The number of recombination hotspots varied from 1 to 12 per chromosome. A high correlation of 0.83 between the distribution of SSR markers and genes suggested close association of SSRs with genes. The knowledge of distribution of recombination on chromosomes may be applied in characterizing and targeting genes

Enzymes in Lymph

Peer Reviewe

Effect of Transient Hypoxia in Skeletal Muscle on Enzyme Activities in Lymph and Plasma

Peer Reviewe

Biological, Analytical and Experimental Components of Variance in a Long-Term Study of Plasma Constituents in Rat

Peer Reviewe

Catalytic Enzyme Activity Concentration in Plasma of Man, Sheep, Dog, Cat, Rabbit, Guinea Pig, Rat and Mouse. Approach to a Quantitative Diagnostic Enzymology. I. Communication

Peer Reviewe

Kinetic of Adjustment of Enzyme Catalytic Concentrations in the Extracellular Space of the Man, the Dog and the Rat. Approach to a Quantitative Diagnostic Enzymology, V. Communication

Peer Reviewe

Catalytic Enzyme Activity Concentration in Thoracic Duct, Liver, and Intestinal Lymph of the Dog, the Rabbit, the Rat and the Mouse. Approach to a Quantitative Diagnostic Enzymology, II. Communication

Peer Reviewe

CrackBerry: The Tales of BlackBerry Use and Abuse

A delayed train, a dip in the conversation, an early morning hour with no sleep - during these moments, do you feel an overwhelming urge to grab your BlackBerry? Do you know someone else who does? If the answer is yes, then look no further than this one-of-a-kind book...CrackBerry: True Tales of Blackberry Use and Abuse covers the phenomenon of "BlackBerry Addiction," offering true-life accounts of BlackBerry dependence and mishaps. You'll find comfort and humor in the unbelievable tales of BlackBerry abuse and also learn some valuable tips along the way. * The definitive guide to respon