23 research outputs found
Idiopathic sclerosing mesenteritis in paediatrics: Report of a successfully treated case and a review of literature
A 6 year old female with symptoms of small bowel obstruction underwent an exploratory laparotomy which revealed widespread evidence of inflammatory fibrotic adhesions involving the jejunal mesentery. In view of persistent growth failure, chronic anaemia, elevated acute phase reactants and imaging evidence of a diffuse progressive inflammatory process, the child was treated with corticosteroids and methotrexate with complete response. The literature on juvenile idiopathic sclerosing mesenteritis has been reviewed
Simultaneous occurrence of pure red cell aplasia and papular-purpuric `gloves and socks' syndrome in parvovirus B-19 infection
Papular-purpuric ‘gloves and socks’ syndrome (PPGSS) has been associated
with parvovirus B-19 infection. We report a case of an adult
immunocompetent male who presented with PPGSS. Bone marrow examination
revealed pure red cell aplasia. Parvovirus B-19 DNA was detected by
polymerase chain reaction in the patient’s serum, whole blood and in the
cutaneous lesions. This report illustrates the variety of clinical
manifestations caused by B-19 infection, presents for the first time the
concurrent appearance of pure red cell aplasia and PPGSS in the same
patient and, finally, suggests that PPGSS may be due to direct lytic
effect of the virus
Visceral leishmaniasis resembling systemic lupus erythematosus
We describe three cases with visceral leishmaniasis (VL) associated with
autoimmune manifestations. The patients presented with anemia,
leukopenia, thrombocytopenia, renal involvement and low complement
levels. Autoimmune features were present (antinuclear and
anticardiolipin antibodies, VDRL, RF, positive direct Coombs’ test),
which subsided after therapy. Leishmaniasis should be taken into
consideration in the differential diagnosis of autoimmune disorders
Granulomatous infection of the hand and wrist due to Azospirillum spp.
We report a case of Azospirillum infection manifestating as granulomatous tenosynovitis of the right hand, in an immunocompetent middle-aged female. We highlight the unusual source of the infection, the diagnostic workup, as well as the treatment approach. © 2013 Elsevier Inc