240 research outputs found
Strong gravitational lensing across dilaton anti-de Sitter black hole
In this work we investigate gravitational lensing effect in strong field
region around a dilaton black holes in an anti de Sitter (ADS) space. We also
analyse the dependence of the radius of the photon sphere and deflection angle
on dilaton coupling and cosmological constant in this black hole space time.
Finally the values of minimum impact parameter, the separation between the
first and the other images as well as the ratio between the flux of the first
image and the flux coming from all the other images are determined to
characterize some possible distinct signatures of such black holes.Comment: 8 pages and 3 figures. Accepted in Physical Review
Schwarzschild black hole lensing
We study strong gravitational lensing due to a Schwarzschild black hole.
Apart from the primary and the secondary images we find a sequence of images on
both sides of the optic axis; we call them {\em relativistic images}. These
images are formed due to large bending of light near r = 3M (the closest
distance of approach r_o is greater than 3M). The sources of the entire
universe are mapped in the vicinity of the black hole by these images. For the
case of the Galactic supermassive ``black hole'' they are formed at about 17
microarcseconds from the optic axis. The relativistic images are not resolved
among themselves, but they are resolved from the primary and secondary images.
However the relativistic images are very much demagnified unless the observer,
lens and source are very highly aligned. Due to this and some other
difficulties the observation of these images does not seem to be feasible in
near future. However, it would be a great success of the general theory of
relativity in a strong gravitational field if they ever were observed and it
would also give an upper bound, r_o = 3.21 M, to the compactness of the lens,
which would support the black hole interpretation of the lensing object.Comment: RevTex, 5 eps files are included, observational difficulties are
discussed and there are some changes in presentatio
A frozen super-Earth orbiting a star at the bottom of the Main Sequence
We observed the microlensing event MOA-2007-BLG-192 at high angular
resolution in JHKs with the NACO adaptive optics system on the VLT while the
object was still amplified by a factor 1.23 and then at baseline 18 months
later. We analyzed and calibrated the NACO photometry in the standard 2MASS
system in order to accurately constrain the source and the lens star fluxes. We
detect light from the host star of MOA-2007-BLG-192Lb, which significantly
reduces the uncertainties in its char- acteristics as compared to earlier
analyses. We find that MOA-2007-BLG-192L is most likely a very low mass late
type M-dwarf (0.084 [+0.015] [-0.012] M\odot) at a distance of 660 [+100] [-70]
pc orbited by a 3.2 [+5.2] [-1.8] M\oplus super-Earth at 0.66 [+0.51] [-0.22]
AU. We then discuss the properties of this cold planetary system.Comment: published version A&A 540, A78 (2012) A&A, 10 pages, 7 Figure
Strong Gravitational Lensing in a Charged Squashed Kaluza- Klein Black hole
In this paper we investigate the strong gravitational lensing in a charged
squashed Kaluza-Klein black hole. We suppose that the supermassive black hole
in the galaxy center can be considered by a charged squashed Kaluza-Klein black
hole and then we study the strong gravitational lensing theory and estimate the
numerical values for parameters and observables of it. We explore the effects
of the scale of extra dimension and the charge of black hole
on these parameters and observables.Comment: 17 pages, 10 figure
Increased shedding of HU177 correlates with worse prognosis in primary melanoma
<p>Abstract</p> <p>Background</p> <p>Increased levels of cryptic collagen epitope HU177 in the sera of melanoma patients have been shown to be associated with thicker primary melanomas and with the nodular histologic subtype. In this study, we investigate the association between HU177 shedding in the sera and clinical outcome in terms of disease-free survival (DFS) and overall survival (OS).</p> <p>Methods</p> <p>Serum samples from 209 patients with primary melanoma prospectively enrolled in the Interdisciplinary Melanoma Cooperative Group at the New York University Langone Medical Center (mean age = 58, mean thickness = 2.09 mm, stage I = 136, stage II = 41, stage III = 32, median follow-up = 54.9 months) were analyzed for HU177 concentration using a validated ELISA assay. HU177 serum levels at the time of diagnosis were used to divide the study cohort into two groups: low and high HU177. DFS and OS were estimated by Kaplan-Meier survival analysis, and the log-rank test was used to compare DFS and OS between the two HU177 groups. Multivariate Cox proportional hazards regression models were employed to examine the independent effect of HU177 category on DFS and OS.</p> <p>Results</p> <p>HU177 sera concentrations ranged from 0-139.8 ng/ml (mean and median of 6.2 ng/ml and 3.7 ng/ml, respectively). Thirty-eight of the 209 (18%) patients developed recurrences, and 34 of the 209 (16%) patients died during follow-up. Higher HU177 serum level was associated with an increased rate of melanoma recurrence (p = 0.04) and with increasing mortality (p = 0.01). The association with overall survival remained statistically significant after controlling for thickness and histologic subtype in a multivariate model (p = 0.035).</p> <p>Conclusions</p> <p>Increased shedding of HU177 in the serum of primary melanoma patients is associated with poor prognosis. Further studies are warranted to determine the clinical utility of HU177 in risk stratification compared to the current standard of care.</p
Coming out with the media: the ritualization of self-disclosure in the Dutch television program Uit de Kast
Using the media to disclose one’s sexual identity has become an increasingly salient practice in recent years. Yet little is known about the reasons for the emergence of this form of self-disclosure. Based on an analysis of the Dutch television programme Uit de Kast (‘Out of the Closet’), this article relates the rise of mediated coming out practices to the ritualizing power of the media: we argue that media plays a quintessential role in transforming the socially unscripted act of coming out into a patterned, culturally meaningful performance. Our analysis reveals that the ritual work of the programme is embedded in the ways 1) the generic format of the show structures the self-disclosures, 2) the authority of the media is deployed to channel the coming out process, and 3) the programme, while controlling diversity, reinforces dominant societal values and ideologies. The case not only highlights how unprecedented ritual forms come to flourish in the current era of ‘participatory’ media culture, but also demonstrates how ritualization supports and naturalizes the claim that media is an effective agent to create order in everyday, ordinary lives
Detection of Extrasolar Planets by Gravitational Microlensing
Gravitational microlensing provides a unique window on the properties and
prevalence of extrasolar planetary systems because of its ability to find
low-mass planets at separations of a few AU. The early evidence from
microlensing indicates that the most common type of exoplanet yet detected are
the so-called "super-Earth" planets of ~10 Earth-masses at a separation of a
few AU from their host stars. The detection of two such planets indicates that
roughly one third of stars have such planets in the separation range 1.5-4 AU,
which is about an order of magnitude larger than the prevalence of gas-giant
planets at these separations. We review the basic physics of the microlensing
method, and show why this method allows the detection of Earth-mass planets at
separations of 2-3 AU with ground-based observations. We explore the conditions
that allow the detection of the planetary host stars and allow measurement of
planetary orbital parameters. Finally, we show that a low-cost, space-based
microlensing survey can provide a comprehensive statistical census of
extrasolar planetary systems with sensitivity down to 0.1 Earth-masses at
separations ranging from 0.5 AU to infinity.Comment: 43 pages. Very similar to chapter 3 of Exoplanets: Detection,
Formation, Properties, Habitability, John Mason, ed. Springer (April 3, 2008
Microlensing as a probe of the Galactic structure; 20 years of microlensing optical depth studies
Microlensing is now a very popular observational astronomical technique. The
investigations accessible through this effect range from the dark matter
problem to the search for extra-solar planets. In this review, the techniques
to search for microlensing effects and to determine optical depths through the
monitoring of large samples of stars will be described. The consequences of the
published results on the knowledge of the Milky-Way structure and its dark
matter component will be discussed. The difficulties and limitations of the
ongoing programs and the perspectives of the microlensing optical depth
technique as a probe of the Galaxy structure will also be detailed.Comment: Accepted for publication in General Relativity and Gravitation.
General Relativity and Gravitation in press (2010) 0
Assessing the clinical utility of measuring Insulin-like Growth Factor Binding Proteins in tissues and sera of melanoma patients
<p>Abstract</p> <p>Background</p> <p>Different Insulin-like Growth Factor Binding Proteins (IGFBPs) have been investigated as potential biomarkers in several types of tumors. In this study, we examined both IGFBP-3 and -4 levels in tissues and sera of melanoma patients representing different stages of melanoma progression.</p> <p>Methods</p> <p>The study cohort consisted of 132 melanoma patients (primary, n = 72; metastatic, n = 60; 64 Male, 68 Female; Median Age = 56) prospectively enrolled in the New York University School of Medicine Interdisciplinary Melanoma Cooperative Group (NYU IMCG) between August 2002 and December 2006. We assessed tumor-expression and circulating sera levels of IGFBP-3 and -4 using immunohistochemistry and ELISA assays. Correlations with clinicopathologic parameters were examined using Wilcoxon rank-sum tests and Spearman-rank correlation coefficients.</p> <p>Results</p> <p>Median IGFBP-4 tumor expression was significantly greater in primary versus metastatic patients (70% versus 10%, p = 0.01) A trend for greater median IGFBP-3 sera concentration was observed in metastatic versus primary patients (4.9 μg/ml vs. 3.4 μg/ml, respectively, p = 0.09). However, sera levels fell within a normal range for IGFBP-3. Neither IGFBP-3 nor -4 correlated with survival in this subset of patients.</p> <p>Conclusion</p> <p>Decreased IGFBP-4 tumor expression might be a step in the progression from primary to metastatic melanoma. Our data lend support to a recently-described novel tumor suppressor role of secreting IGFBPs in melanoma. However, data do not support the clinical utility of measuring levels of IGFBP-3 and -4 in sera of melanoma patients.</p
Nanopore surface coating delivers nanopore size and shape through conductance-based sizing
The performance of nanopore single-molecule sensing elements depends intimately on their physical dimensions and surface chemical properties. These factors underpin the dependence of the nanopore ionic conductance on electrolyte concentration, yet the measured, or modeled, dependence only partially illuminates the details of geometry and surface chemistry. Using the electrolyte-dependent conductance data before and after selective surface functionalization of solid-state nanopores, however, introduces more degrees of freedom and improves the performance of conductance-based nanopore characterizations. Sets of representative nanopore profiles were used to generate conductance data, and the nanopore shape and exact dimensions were identified, through conductance alone, by orders-of-magnitude 3 reductions in the geometry optimization metrics. The optimization framework could similarly be used to evaluate the nanopore surface coating thickness
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