15 research outputs found

    MEKANISME GERAK NAIK TURUN KURSI DOKTER BEDAH TIPE ULIR DAYA

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    Mekanisme gerak naik turun kursi dokter bedah tipe ulir daya dirancang untuk mengatur ketinggian duduk kursi dokter bedah agar menghasilkan posisi nyaman pada saat dipergunakan pada kegiatan bedah. Mekanisme gerak naik turun kursi dokter bedah tipe ulir daya dilengkapi perangkat elektronik berbasis teknologi informasi dan komunikasi untuk mengendalikan motor arus searah memberikan putaran dan torsi sesuai sinyal yang diberikan oleh saklar kaki naik/turun. Mekanisme gerak naik turun kursi dokter bedah tipe ulir daya mempunyai komponen berupa alas duduk berbentuk bujur sangkar yang ditempatkan pada posisi mendatar dan berfungsi sebagai penumpu bagian bawah kursi dokter bedah, alas duduk ditumpu oleh rangka atas; rangka atas memiliki slot tempat meluncurnya engsel peluncur atas, engsel peluncur atas mengubag gerak horisontal manjadi gerak vertikan; perangkat ulir daya berfungsi mengubah arah gerak pitar menjadi gerak linier translasi sekaligus memberi efek mengunci sendiri pada sistem gerak; Motor arus searah berfungsi sebagai sumber torsi dan putaran pada sistem; Baterai sumber daya listrik untuk menggerakan motor arus searah; Rangka berfungsi sebagai penumpu semua komponen yang tidak bergerak; Perangkat elektronik berbasis teknologi informasi dan komunikasi dipergunakan untuk mengontrol gerak putar motor searah/berlawanan jarum jam sehingga sistem dapat bergerak naik atau turun

    Prevalence of back pain among nurses working in Government Health Clinics and Hospital in Port Dickson, Malaysia

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    Introduction : Nursing is an occupation associated with high risk of developing back pain due to their nature of work practices. The aim of this study was to determine the prevalence of back pain among nurses working in government health clinics and hospitals in Port Dickson and the factors associated with it. Methods : A cross sectional study was conducted involving 126 nurses working in government health clinics and district hospital in Port Dickson. They were universally sampled. A self-administered questionnaire, assessing personal and socio-demographic characteristics, back pain, work factors and psychosocial factors. Results : The prevalence of back pain among nurses was 79.4% and factors that showed significant association were workplace (p=0.026) and carried heavy load (p=0.043). Conclusion : Where one work and nature of work one does has been shown in this study to be important issues to be considered in helping to manage back pain related to work. It is also recommended that staff need to be encouraged to do exercise to strengthen the back muscles, increase spinal flexibility and blood circulation to the spine as well as need to be reminded regarding ergonomic adjustment at work

    Kualitas Pelayanan Publik Kecamatan setelah Perubahan Kedudukan dan Fungsi Camat sebagai Perangkat Daerah

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    This research aims to analyze the quality of subdistrict public services in decentralization era, identifyservices dimensions or attributes that are prioritized by subdistrict for a better performance, and conduct comparativestudy to analyze whether a subdistrict with larger delegated authorities has a better quality of public services. The analysiswas conducted using the Service Quality (ServQual) that had been developed into Importance Performance Analysis (IPA).The research was conducted through surveys in two locations i.e. Katapang Subdistrict in Bandung and Dramaga Subdistrictin Bogor, on three types of services namely 1) civil administration/registration services 2). Business license services and 3).Building construction license services.The research result showed that although the subdistricts had legally and formallyshifted into local government institution, the quality of public service performance is still not optimal. This was indicatedby the lower performance index as well as the importance index of the respondents for both subdistricts, in other wordsthere were gaps between respondents perception and respondents expectation on public service quality

    Does urinary peptide content differ between COPD patients with and without inherited alpha-1 antitrypsin deficiency?

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    Alfonso Carleo,1,2,* Joanna Chorostowska-Wynimko,3,* Thomas Koeck,4 Harald Mischak,4,5 Małgorzata Czajkowska-Malinowska,6 Adriana Rozy,3 Tobias Welte,1,2 Sabina Janciauskiene1,2 1Department of Respiratory Medicine, Hannover Medical School, 2Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), DZL Hannover, Germany; 3Department of Genetics and Clinical Immunology, National Institute of Tuberculosis and Lung Diseases, Warsaw, Poland; 4Mosaiques Diagnostics and Therapeutics AG, Hannover, Germany; 5Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK; 6Department of Lung Diseases and Respiratory Failure, Regional Center of Pulmonology, Bydgoszcz, Poland *These authors contributed equally to this work Abstract: Differentiating between chronic obstructive pulmonary disease (COPD) patients with normal (PiMM) or deficient (PiZZ) genetic variants of alpha-1 antitrypsin (A1AT) is important not only for understanding the pathobiology of disease progression but also for improving personalized therapies. This pilot study aimed to investigate whether urinary peptides reflect the A1AT-related phenotypes of COPD. Urine samples from 19 clinically stable COPD cases (7 PiMM and 12 PiZZ A1AT) were analyzed by capillary electrophoresis coupled to mass spectrometry. We identified 66 peptides (corresponding to 36 unique proteins) that differed between PiZZ and PiMM COPD. Among these, peptides from the collagen family were the most abundant and divergent. A logistic regression model based on COL1A1 or COL5A3 peptides enabled differentiation between PiMM and PiZZ groups, with a sensitivity of 100% and specificity of 85.71% for COL1A1 and a sensitivity of 91.67% and specificity of 85.71% for COL5A3. Furthermore, patients with PiZZ presented low levels of urinary peptides involved in lipoproteins/lipids and retinoic acid metabolism, such as apolipoprotein A-I and C4, retinol-binding protein 4 and prostaglandin-H2 d-isomerase. However, peptides of MDS1 and EVII complex locus, gelsolin and hemoglobin alpha were found in the urine of COPD cases with PiZZ, but not with PiMM. These capillary electrophoresis coupled to mass spectrometry-based results provide the first evidence that urinary peptide content differs between PiMM and PiZZ patients with COPD. Keywords: alpha-1 antitrypsin, alpha-1 antitrypsin deficiency, COPD, urine, peptidomics, capillary electrophoresis coupled to mass spectrometry, phenotypes, peptides, biomarkers, collagen&nbsp

    Boosting airway T-regulatory cells by gastrointestinal stimulation as a strategy for asthma control

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    The hallmark of atopic asthma is transient airways hyperresponsiveness (AHR) preceded by aeroallergen-induced Th-cell activation. This is preceded by upregulation of CD86 on resident airway dendritic cells (DCs) that normally lack competence in T-cell triggering. Moreover, AHR duration is controlled via T-regulatory (Treg) cells, which can attenuate CD86 upregulation on DC. We show that airway mucosal Treg/DC interaction represents an accessible therapeutic target for asthma control. Notably, baseline airway Treg activity in sensitized rats can be boosted by microbe-derived stimulation of the gut, resulting in enhanced capacity to control CD86 expression on airway DC triggered by aeroallergen and accelerated resolution of AHR
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