1,987 research outputs found

    NTWO - A nitrogen properties package

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    FORTRAN 4 subroutines to calculate thermodynamic and transport properties of molecular nitroge

    Single- and Multiple-Shell Uniform Sampling Schemes for Diffusion MRI Using Spherical Codes

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    In diffusion MRI (dMRI), a good sampling scheme is important for efficient acquisition and robust reconstruction. Diffusion weighted signal is normally acquired on single or multiple shells in q-space. Signal samples are typically distributed uniformly on different shells to make them invariant to the orientation of structures within tissue, or the laboratory coordinate frame. The Electrostatic Energy Minimization (EEM) method, originally proposed for single shell sampling scheme in dMRI, was recently generalized to multi-shell schemes, called Generalized EEM (GEEM). GEEM has been successfully used in the Human Connectome Project (HCP). However, EEM does not directly address the goal of optimal sampling, i.e., achieving large angular separation between sampling points. In this paper, we propose a more natural formulation, called Spherical Code (SC), to directly maximize the minimal angle between different samples in single or multiple shells. We consider not only continuous problems to design single or multiple shell sampling schemes, but also discrete problems to uniformly extract sub-sampled schemes from an existing single or multiple shell scheme, and to order samples in an existing scheme. We propose five algorithms to solve the above problems, including an incremental SC (ISC), a sophisticated greedy algorithm called Iterative Maximum Overlap Construction (IMOC), an 1-Opt greedy method, a Mixed Integer Linear Programming (MILP) method, and a Constrained Non-Linear Optimization (CNLO) method. To our knowledge, this is the first work to use the SC formulation for single or multiple shell sampling schemes in dMRI. Experimental results indicate that SC methods obtain larger angular separation and better rotational invariance than the state-of-the-art EEM and GEEM. The related codes and a tutorial have been released in DMRITool.Comment: Accepted by IEEE transactions on Medical Imaging. Codes have been released in dmritool https://diffusionmritool.github.io/tutorial_qspacesampling.htm

    A principled approach to the measurement of situation awareness in commercial aviation

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    The issue of how to support situation awareness among crews of modern commercial aircraft is becoming especially important with the introduction of automation in the form of sophisticated flight management computers and expert systems designed to assist the crew. In this paper, cognitive theories are discussed that have relevance for the definition and measurement of situation awareness. These theories suggest that comprehension of the flow of events is an active process that is limited by the modularity of attention and memory constraints, but can be enhanced by expert knowledge and strategies. Three implications of this perspective for assessing and improving situation awareness are considered: (1) Scenario variations are proposed that tax awareness by placing demands on attention; (2) Experimental tasks and probes are described for assessing the cognitive processes that underlie situation awareness; and (3) The use of computer-based human performance models to augment the measures of situation awareness derived from performance data is explored. Finally, two potential example applications of the proposed assessment techniques are described, one concerning spatial awareness using wide field of view displays and the other emphasizing fault management in aircraft systems

    Pilot opinions on high level flight deck automation issues: Toward the development of a design philosophy

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    There has been much concern in recent years about the rapid increase in automation on commercial flight decks. The survey was composed of three major sections. The first section asked pilots to rate different automation components that exist on the latest commercial aircraft regarding their obtrusiveness and the attention and effort required in using them. The second section addressed general 'automation philosophy' issues. The third section focused on issues related to levels and amount of automation. The results indicate that pilots of advanced aircraft like their automation, use it, and would welcome more automation. However, they also believe that automation has many disadvantages, especially fully autonomous automation. They want their automation to be simple and reliable and to produce predictable results. The biggest needs for higher levels of automation were in pre-flight, communication, systems management, and task management functions, planning as well as response tasks, and high workload situations. There is an irony and a challenge in the implications of these findings. On the one hand pilots would like new automation to be simple and reliable, but they need it to support the most complex part of the job--managing and planning tasks in high workload situations

    Cost Burden of Illness for Hepatitis C Patients with Employer-Sponsored Health Insurance

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    The disease burden of hepatitis C virus (HCV) is expected to more than double in the next two decades. Currently, there is very little information about the costs of HCV treatment for employers who pay for treatment and health plans that cover HCV patients. This study reports the medical costs of HCV for workers with health insurance. A retrospective claims data design was used for this study. A sample of HCV patients with health insurance was drawn from the inpatient, outpatient, and enrollment files of the MEDSTAT Group's MarketScan family of databases for 1993-1998. Patients were grouped into cohorts and studied for up to 2 years before and after HCV diagnosis. Sample size varies according to length of follow-up, peaking at 3,077 patients enrolled for at least 6 months. In the first year following HCV diagnosis, average payments for HCV patients (10,925)werealmostsixtimesashighaspaymentsforallpatientsintheMarketScandatabase(10,925) were almost six times as high as payments for all patients in the MarketScan database (1,186). Doctors are encouraged to test high-risk patients to find HCV patients earlier in the course of their disease and to better manage their care in order to avoid unnecessary illness and expenses for this disease.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/63140/1/109350702320229195.pd

    Tweeting about sexism motivates further activism: A social identity perspective

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    Women, more so than men, are using social media activism to respond to sexism. However, when they do, they are also faced with gendered criticisms (\u27hashtag feminism\u27) that may instead serve to silence them. Based in social identity theory, this research examined how women\u27s social media activism, in response to sexism, may be a first step toward further activism. Two studies used a simulated Twitter paradigm to expose women to sexism and randomly assigned them to either tweet in response, or to a no-tweet control condition. Both studies found support for a serial mediation model such that tweeting after sexism strengthened social identity, which in turn increased collective action intentions, and in turn, behavioural collective actions. Study 2 further showed that validation from others increases the indirect effect of tweeting on behavioural collective action through collective action intentions, but group efficacy did not moderate any indirect effects. It was concluded that when social media activism in response to sexism promotes an enactment of women’s social identity, thereby mobilizing them to further action

    Quantitative evaluation of neuropharmacological trials

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/116906/1/cpt1974153229.pd
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