474 research outputs found
Analysis of short-term dynamic in vivo response of E. coli to alternative substrate perturbations
VLBA Imaging of the OH Maser in IIIZw35
We present a parsec-scale image of the OH maser in the nucleus of the active
galaxy IIIZw35, made using the Very Long Baseline Array at a wavelength of 18
cm. We detected two distinct components, with a projected separation of 50 pc
(for D=110 Mpc) and a separation in Doppler velocity of 70 km/s, which contain
50% of the total maser flux. Velocity gradients within these components could
indicate rotation of clouds with binding mass densities of ~7000 solar masses
per cubic parsec, or total masses of more than 500,000 solar masses. Emission
in the 1665-MHz OH line is roughly coincident in position with that in the
1667-MHz line, although the lines peak at different Doppler velocities. We
detected no 18 cm continuum emission; our upper limit implies a peak apparent
optical depth greater than 3.4, assuming the maser is an unsaturated amplifier
of continuum radiation.Comment: 10 pages, 3 figure
Pitfalls in interpreting red blood cell parameters in elite high-altitude and sea-level athletes:A unique case series
Standard routine hematological measurements are commonly used to investigate differences in blood parameters between high-altitude athletes (HAA) and sea-level athletes (SLA), and to monitor the effect of high-altitude training. In this way, red blood cell (RBC) parameters are usually expressed as relative parameters (concentration) rather than absolute parameters (total amount). In this unique case series of elite HAA and SLA, we describe how different ways of parameter expression can affect the interpretation of blood tests. In a group of 42 elite athletes, relative and absolute RBC parameters were compared between HAA and SLA. Absolute parameters were calculated by multiplying relative values with formula-based estimated blood volume (BV-e). Additionally, in two individual athletes, one HAA and one SLA, absolute parameters were also calculated with blood volume (BV) obtained by measurement with a dilution method (BV-m). In men, HAA had a significantly higher hemoglobin (Hb) concentration (+7.8%; p = 0.001) and total Hb mass per kg body weight (BW) (+12.0%; p = 0.002). When not corrected for BW, HAA had a lower, non-significant, total Hb mass (-7.8%; p = 0.055). In women, no significant differences between HLA and SLA were observed. The two individual athletes showed that, based on BV-m, in the HAA, total Hb mass and total Hb mass per kg BW were respectively 14.1 and 31.0% higher than in the SLA, whereas based on BV-e, in the HAA, total Hb mass was 20.8% lower and total Hb mass per kg BW was only 2.4% higher. Similar inconsistencies were observed for total RBC count. Thus, different ways of parameter expression, and different methods of BV assessment for the calculation of absolute parameter values, influence the interpretation of blood tests in athletes, which may lead to misinterpretation and incorrect conclusions
The Distribution of Nickel in the West-Atlantic Ocean, Its Relationship With Phosphate and a Comparison to Cadmium and Zinc
Nickel (Ni) is a bio-essential element required for the growth of phytoplankton. It is the least studied bio-essential element, mainly because surface ocean Ni concentrations are never fully depleted and Ni is not generally considered to be a limiting factor. However, stimulation of growth after Ni addition has been observed in past experiments when seemingly ample ambient dissolved Ni was present, suggesting not all dissolved Ni is bio-available. This study details the distribution of Ni along the GEOTRACES GA02 Atlantic Meridional section. Concentrations of Ni were lowest in the surface ocean and the lowest observed concentration of 1.7 nmol kg(-1) was found in the northern hemisphere (NH). The generally lower surface concentrations in the NH subtropical gyre compared to the southern hemisphere (SH), might be related to a greater Ni uptake by nitrogen fixers that are stimulated by iron (Fe) deposition. The distribution of Ni resembles the distribution of cadmium (Cd) and also features a so called kink (change in the steepness of slope) in the Ni-PO4 relationship. Like for Cd, this is caused by the mixing of Nordic and Antarctic origin water masses. The overall distribution of Ni is driven by mixing with an influence of regional remineralization. This influence of remineralization is, with a maximum remineralization contribution of 13% of the highest observed concentration, smaller than for Cd (30%), but larger than for zinc (Zn; 6%). The uptake pattern in the formation regions of Antarctic origin water masses is suggested to be more similar to Zn than to Cd, however, the surface concentrations of Ni are never fully depleted. This results in a North Atlantic concentration distribution of Ni where the trends of increasing and decreasing concentrations between water masses are similar to those observed for Cd, but the actual concentrations as well as the uptake and remineralization patterns are different between these elements
Flux and metabolite flexibility in Escherichia coli at seconds time scale in response to rapid shifts of substrate excess
Transition Voltage Spectroscopy and the Nature of Vacuum Tunneling
Transition Voltage Spectroscopy (TVS) has been proposed as a tool to analyze
charge transport through molecular junctions. We extend TVS to Au-vacuum-Au
junctions and study the distance dependence of the transition voltage V_t(d)
for clean electrodes in cryogenic vacuum. On the one hand, this allows us to
provide an important reference for V_t(d)-measurements on molecular junctions.
On the other hand, we show that TVS forms a simple and powerful test for vacuum
tunneling models
Risk Factors, Dynamics, and Clinical Consequences of Aortic Neck Dilatation after Standard Endovascular Aneurysm Repair
Objective: Aortic neck dilatation (AND) occurs after endovascular aneurysm repair (EVAR) with self expanding stent grafts (SESs). Whether it continues, ultimately exceeding the endograft diameter leading to abdominal aortic aneurysm (AAA) rupture, remains uncertain. Dynamics, risk factors, and clinical relevance of AND were investigated after EVAR with standard SESs.
Methods: All intact EVAR patients treated from 2000 to 2015 at a tertiary institution were included. Demographic, anatomical, and device related characteristics were investigated as risk factors for AND. Outer to outer diameters were measured at a single standardised aortic level on reconstructed computed tomography (CT) images.
Results: A total of 460 patients were included (median follow up 5.2 years, interquartile range [IQR] 3.0, 7.7 years; CT imaging follow up 3.3 years, IQR 1.3, 5.4). Baseline neck diameter was 24 mm (IQR 22, 26) and increased 11.1% (IQR 1.5%, 21.9%) at last CT imaging. Endograft oversizing was 20.0% (IQR 13.6, 28.0). AND was greater during the first year (5.2% [IQR 0, 11.7]) decreasing subsequently (two to four years to 1.4%/year [IQR 0.0, 4.5%], p ≤ .001) and was associated with suprarenal fixation endografts (t value = 7.9, p 5 mm (HR 3.1, 95% CI 1.4 - 6.9).
Conclusion: AND after EVAR with SES is associated with endograft oversizing and radial force but decelerates after the first post-operative year. Baseline aortic neck diameter and suprarenal stent bearing endografts were associated with an increased risk of AND beyond nominal stent graft diameter. However, it remains unclear whether patient selection, differences in endograft radial force or the suprarenal stent are accountable for this difference.info:eu-repo/semantics/publishedVersio
Polarization Observations of 1720 MHz OH Masers toward the Three Supernova Remnants W28, W44, and IC443
(abridged) - We present arcsecond resolution observations from the VLA of the
satellite line of the hydroxyl molecule (OH) at 1720.53 MHz toward three
Galactic supernova remnants: W28, W44 and IC443. All of our observations are
consistent with a model in which the OH(1720 MHz) is collisionally excited by
H2 molecules in the postshock gas heated by a non-dissociative shock. Supernova
remnants with OH(1720 MHz) maser emission may be promising candidates to
conduct high energy searches for the sites of cosmic ray acceleration.Comment: ApJ Let (accepted). Hardcopies available from [email protected]
- …