The orosomucoid 1 protein (α1 acid glycoprotein) is overexpressed in odontogenic myxoma

Odontogenic myxoma (OM) is a benign, but locally invasive, neoplasm occurring in the jaws. However, the molecules implicated in its development are unknown. OM as well as Dental Follicle (DF), an odontogenic tissue surrounding the enamel organ, is derived from ectomesenchymal/mesencyhmal elements. To identify some protein that could participate in the development of this neoplasm, total proteins from OM were separated by two-dimensional electrophoresis and the profiles were compared with those obtained from DF, used as a control

Induction motor control by individual channel analysis and design

A novel control strategy for an induction motor is presented. It consists of a linear, diagonal, low order, minimum phase, robust, and stable multivariable controller (for the electrical subsystem); a Space Vector Pulse Width Modulated Voltage Source Inverter; a low order, minimum phase, robust, and stable SISO controller (for the mechanical component); and a reduced order observer for the rotor field angle estimation. The electrical subsystem control is achieved by the application of Individual Channel Analysis and Design. Robustness is proved through the analysis of the Multivariable Structure Function. The scheme has an adequate performance under the variations of rotor speed, load torque, and parameters –thus providing a simple alternative for Field– Oriented and/or Direct Torque Controlled induction motors

Modificación de procedimiento Dautrey en dislocación recurrente mandibular.

El manejo de la dislocación recurrente mandibular, puede representar un reto para el Cirujano Maxilofacial. La decisión tomada debe ser de acuerdo a las demandas de cada caso en particular. El presente caso fue tratado quirúrgicamente mediante el procedimiento Dautrey, debido a la dislocación recurrente crónica unilateral derecha de la articulación temporomandibular. Este procedimiento no perturba el movimiento funcional normal de la articulación, por otra parte previene la excursión excesiva anterior del cóndilo. La técnica quirúrgica propuesta, presenta una modificación al procedimiento original. Con resultados finales favorables para la función

The orosomucoid 1 protein (α1 acid glycoprotein) is overexpressed in odontogenic myxoma

Abstract Background Odontogenic myxoma (OM) is a benign, but locally invasive, neoplasm occurring in the jaws. However, the molecules implicated in its development are unknown. OM as well as Dental Follicle (DF), an odontogenic tissue surrounding the enamel organ, is derived from ectomesenchymal/mesencyhmal elements. To identify some protein that could participate in the development of this neoplasm, total proteins from OM were separated by two-dimensional electrophoresis and the profiles were compared with those obtained from DF, used as a control. Results We identified eight proteins with differential expression; two of them were downregulated and six upregulated in OM. A spot consistently overexpressed in odontogenic myxoma, with a molecular weight of 44-kDa and a pI of 3.5 was identified as the orosomucoid 1 protein. Western blot experiments confirmed the overexpression of this protein in odontogenic myxoma and immunohistochemical assays showed that this protein was mainly located in the cytoplasm of stellate and spindle-shaped cells of this neoplasm. Conclusion Orosomucoid 1, which belongs to a group of acute-phase proteins, may play a role in the modulation of the immune system and possibly it influences the development of OM.</p