17 research outputs found
Alternative mechanisms of structuring biomembranes: Self-assembly vs. self-organization
We study two mechanisms for the formation of protein patterns near membranes
of living cells by mathematical modelling. Self-assembly of protein domains by
electrostatic lipid-protein interactions is contrasted with self-organization
due to a nonequilibrium biochemical reaction cycle of proteins near the
membrane. While both processes lead eventually to quite similar patterns, their
evolution occurs on very different length and time scales. Self-assembly
produces periodic protein patterns on a spatial scale below 0.1 micron in a few
seconds followed by extremely slow coarsening, whereas self-organization
results in a pattern wavelength comparable to the typical cell size of 100
micron within a few minutes suggesting different biological functions for the
two processes.Comment: 4 pages, 5 figure
Journal of the American Veterinary Medical Association 193 7 850 853 UNITED STATES
Chronic constipation, nonresponsive to medical management and associated with idiopathic megacolon, was diagnosed in 38 cats from 1979 to 1985. All cats were treated by subtotal colectomy and enterocolostomy, in which the ileum or distal portion of the jejunum was joined to a 2- to 4-cm segment of distal portion of the colon preserved to accommodate an end-to-end anastomosis. After surgery, cats usually were depressed and anorectic, had tenesmus, and passed liquid tarry feces. In 37 cats 1 week to 3 months after surgery, character of the feces changed from diarrhea to soft semiformed or formed feces. One cat had severe diarrhea that was nonresponsive to diet change and pharmacologic treatment; the diarrhea resolved after 4.5 months. One cat developed a stricture of the enterocolostomy, which was relieved by 3 balloon catheter dilatations. All cats regained normal appetite, did not lose weight, and were not incontinent. Three cats had sporadic episodes of constipation and were easily treated. Results of histologic examination of the resected portion of colon in 23 cats were inconclusive
On the use of analytical approximate expressions for the transfer rate in excitation transfer kinetics
SIGLECNRS RP 195 (38) / INIST-CNRS - Institut de l'Information Scientifique et TechniqueFRFranc