388 research outputs found

    Biases toward defendants in joint criminal trials

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    Under the Criminal Code Compilation Act 1913 (WA), any number of individuals may be joined as co-defendants in a single trial, fanning a situation known as a joint trial. The charge/s against each defendant are considered separately and given a separate verdict by the jury. There is considerable debate in the legal arena as to the utility of joint trials, although to date little empirical research exists to substantiate any of the claims made. The present study aimed to contribute to the sparse knowledge base on joint trials by examining the impact of evidence strength on juror decision making in joint and single trials of the same defendant. Sixty mock juror university students were required to listen to an audiotaped trial summary about a hypothetical assault case that followed the same procedure as would be followed in Australian criminal courts. Evidence strength was manipulated so that defendant A had relatively weak and circumstantial evidence implicating him in the offence, and defendant B had very strong, substantive evidence implicating him in the offence. Two pilot studies confirmed that this manipulation was successful. The participants were assigned to one of three conditions - the single trial of defendant A, the single trial of defendant B, or the joint trial of defendants A and B. After listening to the trial summary, the participants were then required to give a verdict for the defendant/s, and rate the strength of the prosecution and defence evidence presented for the defendant/s. The hypothesis that the effect of joining their trials will be different for defendants A and B in terms of the proportion of guilty verdicts rendered for each defendant was supported. It was found that defendant A was significantly more likely to be found guilty in the joined condition than in the single condition (p \u3c .05). There was no such effect observed for defendant B (p \u3e .05). The second hypothesis that the effect of joining their trials will be different for defendants A and B on the perceived strength of prosecution evidence was also supported. Statistical testing revealed that there was a significant increase in the perceived strength of the prosecution evidence for defendant A in the joint condition, as c0mpared to the single condition (p \u3c .05). There was no significant difference between the prosecution evidence strength ratings for defendant 8 in the single and joint conditions (p \u3e .05). There was no support for the hypothesis that the effect of joining their trials will be different for defendants A and B on the perceived strength of defence evidence. For both defendants, there was no significant difference between defence evidence strength ratings in the joined and single conditions (p \u3e.05). These results are interpreted with reference to impression formation theory. The limitations of the present study, including the sample, trial medium, trial elements, consequentiality of the task, and the trial materials are discussed. Directions for future research, such as improvements in the present study and additional sources of bias that may influence verdicts in joint trials, are also examined

    Colloidal Dynamics on Disordered Substrates

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    Using Langevin simulations we examine driven colloids interacting with quenched disorder. For weak substrates the colloids form an ordered state and depin elastically. For increasing substrate strength we find a sharp crossover to inhomogeneous depinning and a substantial increase in the depinning force, analogous to the peak effect in superconductors. The velocity versus driving force curve shows criticality at depinning, with a change in scaling exponent occuring at the order to disorder crossover. Upon application of a sudden pulse of driving force, pronounced transients appear in the disordered regime which are due to the formation of long-lived colloidal flow channels.Comment: 4 pages, 4 postscript figure

    Association of individual-socioeconomic variation in quality-of-primary care with area-level service organisation: A multilevel analysis using linked data

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    Rationale, Aims and Objectives: Ensuring equitable access to primary care (PC) contributes to reducing differences in health related to people's socioeconomic circumstances. However, there is limited data on system-level factors associated with equitable access to high-quality PC. We examine whether individual-level socioeconomic variation in general practitioner (GP) quality-of-care varies by area-level organisation of PC services. Methods: Baseline data (2006–2009) from the Sax Institute's 45 and Up Study, involving 267,153 adults in New South Wales, Australia, were linked to Medicare Benefits Schedule claims and death data (to December 2012). Small area-level measures of PC service organisation were GPs per capita, bulk-billing (i.e., no copayment) rates, out-of-pocket costs (OPCs), rates of after-hours and chronic disease care planning/coordination services. Using multilevel logistic regression with cross-level interaction terms we quantified the relationship between area-level PC service characteristics and individual-level socioeconomic variation in need-adjusted quality-of-care (continuity-of-care, long-consultations, and care planning), separately by remoteness. Results: In major cities, more bulk-billing and chronic disease services and fewer OPCs within areas were associated with an increased odds of continuity-of-care—more so among people of high- than low education (e.g., bulk-billing interaction with university vs. no school certificate 1.006 [1.000, 1.011]). While more bulk-billing, after-hours services and fewer OPCs were associated with long consultations and care planning across all education levels, in regional locations alone, more after-hours services were associated with larger increases in the odds of long consultations among people with low- than high education (0.970 [0.951, 0.989]). Area GP availability was not associated with outcomes. Conclusions: In major cities, PC initiatives at the local level, such as bulk-billing and after-hours access, were not associated with a relative benefit for low- compared with high-education individuals. In regional locations, policies supporting after-hours access may improve access to long consultations, more so for people with low- compared with high-education

    The effect of temperature on the viability of human mesenchymal stem cells

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    Introduction Impaction allograft with cement is a common technique used in revision hip surgeries for the last 20 years. However, its clinical results are inconsistent. Recent studies have shown that mesenchymal stem cells (MSCs) seeded onto allograft can enhance bone formation. This in vitro study investigates whether the increase in temperature related to the polymerisation of bone cement will affect the viability of human MSCs. Methods The viability of human MSCs was measured after incubating them at temperatures of 38°C, 48°C and 58°C; durations 45 seconds, 80 seconds and 150 seconds. A control group was kept at 37°C and 5% carbon dioxide for the duration of the investigation (7 days). During the course of the study the human MSCs were analysed for cell metabolic activity using the alamarBlue™ assay, cell viability using both Trypan Blue dye exclusion and calcein staining under fluorescent microscopy, and necrosis and apoptosis using Annexin V and propidium iodide for flow cytometric analysis. A one-way analysis of variance with a priori Dunnett’s test was used to indicate the differences between the treatment groups, when analysed against the control. This identified conditions with a significant difference in cell metabolic activity (alamarBlue™) and cell viability (Trypan Blue). Results Results showed that cell metabolism was not severely affected up to 48°C/150 seconds, while cells in the 58°C group died. Similar results were shown using Trypan Blue and calcein analysis for cell viability. No significant difference in apoptosis and necrosis of the cells was observed when human MSCs treated at 48°C/150 seconds were compared with the control group. Conclusions The study suggests that human MSCs seeded onto allograft can be exposed to temperatures up to 48°C for 150 seconds. Exposure to this temperature for this time period is unlikely to occur during impaction allograft surgery when cement is used. Therefore, in many situations, the addition of human MSCs to cemented impaction grafting may be carried out without detrimental effects to the cells. Furthermore, previous studies have shown that this can enhance new bone formation and repair the defects in revision situations

    Income-related inequalities in chronic conditions, physical functioning and psychological distress among older people in Australia: cross-sectional findings from the 45 and up study

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    BACKGROUND: The burden of chronic disease continues to rise as populations age. There is relatively little published on the socioeconomic distribution of this burden in older people. This study quantifies absolute and relative income-related inequalities in prevalence of chronic diseases, severe physical functioning limitation and high psychological distress in mid-age and older people in Australia. METHODS: Cross-sectional study of 208,450 participants in the 45 and Up Study, a population-based cohort of men and women aged 45–106 years from New South Wales, Australia. Chronic conditions included self-reported heart disease, diabetes, Parkinson’s disease, cancer and osteoarthritis; physical functioning limitation (severe/not) was measured using Medical Outcomes Study measures and psychological distress (high/not) using the Kessler Psychological Distress Scale. For each outcome, prevalence was estimated in relation to annual household income (6 categories). Prevalence differences (PDs) and ratios (PRs) were generated, comparing the lowest income category (<20,000)tothehighest(20,000) to the highest (≥70,000), using Poisson regression with robust standard errors, weighted for age, sex and region of residence. Analyses were stratified by age group (45–64, 65–79 and ≥80 years) and sex and adjusted for age and country of birth. RESULTS: With few exceptions, there were income gradients in the prevalence of chronic conditions among all age-sex groups, with prevalence decreasing with increasing income. Of the chronic diseases, PDs were highest for diabetes (ranging between 5.69% and 10.36% across age-sex groups) and in women, also for osteoarthritis (5.72% to 8.14%); PRs were highest for osteoarthritis in men aged 45–64 years (4.01), otherwise they were highest for diabetes (1.78 to 3.43). Inequalities were very high for both physical functioning limitation and psychological distress, particularly among those aged 45–64 (PDs between 18.67% and 29.23% and PRs between 4.63 and 16.51). Absolute and relative inequalities tended to decrease with age, but remained relatively high for diabetes and physical functioning in the elderly (≥80 years). CONCLUSIONS: Significant inequalities in the prevalence of chronic conditions, physical functioning and psychological distress persist into old age. The additional health burden placed on those who are already disadvantaged is likely to become an increasingly important issue in an ageing population

    Examining area-level variation in service organisation and delivery across the breadth of primary healthcare. Usefulness of measures constructed from routine data

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    Australia has a universal healthcare system, yet organisation and delivery of primary healthcare (PHC) services varies across local areas. Understanding the nature and extent of this variation is essential to improve quality of care and health equity, but this has been hampered by a lack of suitable measures across the breadth of effective PHC systems. Using a suite of measures constructed at the area-level, this study explored their application in assessing area-level variation in PHC organisation and delivery. Routinely collected data from New South Wales, Australia were used to construct 13 small area-level measures of PHC service organisation and delivery that best approximated access (availability, affordability, accommodation) comprehensiveness and coordination. Regression analyses and pairwise Pearson’s correlations were used to examine variation by area, and by remoteness and area disadvantage. PHC service delivery varied geographically at the small-area level–within cities and more remote locations. Areas in major cities were more accessible (all measures), while in remote areas, services were more comprehensive and coordinated. In disadvantaged areas of major cities, there were fewer GPs (most disadvantaged quintile 0.9[SD 0.1] vs least 1.0[SD 0.2]), services were more affordable (97.4%[1.6] bulk-billed vs 75.7[11.3]), a greater proportion were after-hours (10.3%[3.0] vs 6.2[2.9]) and for chronic disease care (28%[3.4] vs 17.6[8.0]) but fewer for preventive care (50.7%[3.8] had cervical screening vs 62.5[4.9]). Patterns were similar in regional locations, other than disadvantaged areas had less after-hours care (1.3%[0.7] vs 6.1%[3.9]). Measures were positively correlated, except GP supply and affordability in major cities (-0.41, p < .01). Application of constructed measures revealed inequity in PHC service delivery amenable to policy intervention. Initiatives should consider the maldistribution of GPs not only by remoteness but also by area disadvantage. Avenues for improvement in disadvantaged areas include preventative care across all regions and after-hours care in regional locations

    Time-dependent moments from partial differential equations and the time-dependent set of atoms

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    We study the time-dependent moments sα(t)=xαf(x,t) dxs_\alpha(t) = \int x^\alpha\cdot f(x,t)~\mathrm{d} x of the solution ff of the partial differential equation tf=νΔf+gf+hf\partial_t f = \nu\Delta f + g\cdot\nabla f + h\cdot f with initial Schwartz function data f0S(Rn)f_0\in\mathcal{S}(\mathbb{R}^n). At first we describe the dual action on the polynomials, i.e., the time-evolution of ff is completely moved to the polynomial side sα(t)=p(x,t)f0(x) dxs_\alpha(t) = \int p(x,t)\cdot f_0(x)~\mathrm{d} x. We investigate the special case of the heat equation. We find that several non-negative polynomials which are not sums of squares become sums of squares under the heat equation in finite time. Finally, we solve the problem of moving atoms under the equation tf=gf+hf\partial_t f = g\cdot\nabla f + h\cdot f with f0=μ0f_0 = \mu_0 being a finitely atomic measure. We find that in the time evolution μt=i=1kci(t)δxi(t)\mu_t = \sum_{i=1}^k c_i(t)\cdot \delta_{x_i(t)} the atom positions xi(t)x_i(t) are governed only by the transport term gg\cdot\nabla and that the time-dependent coefficients ci(t)c_i(t) have an analytic solution depending on xi(t)x_i(t)

    Dumbbell transport and deflection in a spatially periodic potential

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    We present theoretical results on the deterministic and stochastic motion of a dumbbell carried by a uniform flow through a three-dimensional spatially periodic potential. Depending on parameters like the flow velocity, there are two different kinds of movement: transport along a potential valley and stair-like motion oblique to the potential trenches. The crossover between these two regimes, as well as the deflection angle, depends on the size of the dumbbell. Moreover, thermal fluctuations cause a resonance-like variation in the deflection angle as a function of the dumbbell extension.Comment: 5 pages, 8 figure

    Mesothelioma trends in the ACT and comparisons with the rest of Australia

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    OBJECTIVES Inhalation of asbestos fibres is the predominant cause of malignant mesothelioma. Domestic exposure to asbestos is a major community concern in the Australian Capital Territory (ACT) because of loose-fill asbestos home insulation. Little is known about how trends in mesothelioma rates in the ACT compare with those elsewhere. The objective of this study was to describe trends in mesothelioma rates in the ACT and compare them with those for the rest of Australia. METHODS We used de-identified data from the ACT Cancer Registry (1982- 2014), and the Western Australia (WA) Cancer Registry and the Australian Cancer Database (1982-2011). We calculated crude mesothelioma rates, by 3-year periods, for the ACT and for the rest of Australia (excluding WA). We used Poisson regression to analyse mesothelioma trends from 1994 to 2011 (complete reporting period) using an indirect standardisation approach to adjust for age and sex. RESULTS There were 140 mesothelioma cases reported to the ACT Cancer Registry between 1982 and 2014 - 81% male and 19% female. Between 1994 and 2011, age- and sex-adjusted mesothelioma rates in the ACT increased over time, on average by 12% per 3-year period (relative risk [RR] 1.12; 95% confidence interval [CI] 0.99, 1.26). Compared with the rest of Australia (excluding WA), ACT rates were, on average, lower (RR 0.84; 95% CI 0.69, 1.02), but they increased at a higher rate (RR 1.12 per 3-year period; 95% CI 0.99, 1.27). These results are strongly influenced by the higher rate of mesothelioma observed in the ACT in 2009-2011, when ACT rates became similar to those for the rest of Australia (excluding WA). CONCLUSIONS Although mesothelioma rates may have increased more in the ACT than the rest of Australia (excluding WA) during the past two decades, there is considerable uncertainty in the trends. More information is needed regarding the health risks associated with living in a house with loose-fill asbestos insulation. This is the subject of further studies within the ACT Asbestos Health Study.Includes Appendix table: Number of mesothelioma cases and person-years (PY) by sex, age group and year, ACT, 1982 to 201
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