265 research outputs found
Quality assurance and evaluation (QAE) in Scotland: promoting self-evaluation within and beyond the country
This article looks at policy for quality assurance and evaluation in Scotland, its history and more recent developments, and in particular, at the emphasis on school self-evaluation. It examines the history of the concept, its constituent elements and the role of the Inspectorate in establishing it. Further, the article discusses the Scottish self-evaluation model as a means of promoting the countryâs distinctive identity in education within a European frame. It discusses the role of the Standing International Conference of Inspectorates as a major forum for the transmission of ideas about self-evaluation that illuminates the role of networks in promoting Europeanisation
Systems of education governance and cultures of justice in Ireland, Scotland and Pakistan
This chapter compares the issue of cultures of justice in the systems of education governance in three education systems: Ireland, Scotland and Pakistan. The focus for the comparison are the current policies which shape the regulation of education. These policies were reviewed to identify key issues relating to social justice and equality, decision-making and accountability. From the analysis of each system, three central issues were identified: firstly, the improvement of a state education system; secondly, the degree of decentralisation and centralisation in governance structures and thirdly, the expectations placed on school leaders. The chapter concludes by discussing the tensions between the drive for system improvement and opportunities for school leaders to build strategies to address issues of inequality in schools
Re-Inventing Public Education:The New Role of Knowledge in Education Policy-Making
This article focuses on the changing role of knowledge in education policy making within the knowledge society. Through an examination of key policy texts, the Scottish case of Integrated Children Services provision is used to exemplify this new trend. We discuss the ways in which knowledge is being used in order to re-configure education as part of a range of public services designed to meet individuals' needs. This, we argue, has led to a 'scientization' of education governance where it is only knowledge, closely intertwined with action (expressed as 'measures') that can reveal problems and shape solutions. The article concludes by highlighting the key role of knowledge policy and governance in orienting education policy making through a re-invention of the public role of education
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Faster than light (microscopy): superiority of digital pathology over microscopy for assessment of immunohistochemistry
YesDigital pathology offers the potential for significant benefits in diagnostic pathology, but currently the efficiency of slide viewing is a barrier to adoption. We hypothesised that presenting digital slides for simultaneous viewing of multiple sections of tissue for comparison, as in those with immunohistochemical panels, would allow pathologists to review cases more quickly.
Novel software was developed to view synchronised parallel tissue sections on a digital pathology workstation. Sixteen histopathologists reviewed three liver biopsy cases including an immunohistochemical panel using the digital microscope, and three different liver biopsy cases including an immunohistochemical panel using the light microscope. The order of cases and interface was fully counterbalanced. Time to diagnosis was recorded and mean times are presented as data approximated to a normalised distribution.
Mean time to diagnosis was 4âmin 3âs using the digital microscope and 5âmin 24âs using the light microscope, saving 1âmin 21âs (95%âCI 16âs to 2âmin 26âs; p=0.02), using the digital microscope. Overall normalised mean time to diagnosis was 85% on the digital pathology workstation compared with 115% on the microscope, a relative reduction of 26%.
With appropriate interface design, it is quicker to review immunohistochemical slides using a digital microscope than the conventional light microscope, without incurring any major diagnostic errors. As digital pathology becomes more integrated with routine clinical workflow and pathologists increase their experience of the technology, it is anticipated that other tasks will also become more time-efficient
Soft X-ray emission from a CO 2 laser-heated Z-pinch plasma
We report results of soft X-ray measurements in which a high-power (10 10 â10 11 W/cm 2 ) CO 2 laser was used to heat a near critical density (<10 19 cm â3 ) helium Z-pinch plasma. Frequency-integrated X-ray data show that the unheated Z-pinch plasma is Maxwellian with a temperature of about 30 eV. During laser heating, the X-ray emissions were enhanced over the unheated emissions. Analysis of the experimental X-ray spectra indicate that the low-energy portion of the X-ray emission spectrum (up to 600 eV) is enhanced over the baseline 30 eV Maxwellian emissions. This result is consistent with an inverse bremsstrahlung-modified distribution which results when the plasma heating rate is more rapid than the collisional thermalization rate. These results suggest that it may be possible to enhance the soft X-ray yield of a plasma lithographic source with laser heating.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/45479/1/11090_2005_Article_BF01016523.pd
The altered expression of α1 and ÎČ3 subunits of the gamma-aminobutyric acid A receptor is related to the hepatitis C virus infection
The modulation of the gamma-aminobutyric acid type A (GABA A) receptors activity was observed in several chronic hepatitis failures, including hepatitis C. The expression of GABA A receptor subunits α1 and ÎČ3 was detected in peripheral blood mononuclear cells (PBMCs) originated from healthy donors. The aim of the study was to evaluate if GABA A α1 and ÎČ3 expression can also be observed in PBMCs from chronic hepatitis C (CHC) patients and to evaluate a possible association between their expression and the course of hepatitis C virus (HCV) infection. GABA A α1- and ÎČ3-specific mRNAs presence and a protein expression in PBMCs from healthy donors and CHC patients were screened by reverse transcription polymerase chain reaction (RT-PCR) and Western blot, respectively. In patients, HCV RNA was determined in sera and PBMCs. It was shown that GABA A α1 and ÎČ3 expression was significantly different in PBMCs from CHC patients and healthy donors. In comparison to healthy donors, CHC patients were found to present an increase in the expression of GABA A α1 subunit and a decrease in the expression of ÎČ3 subunit in their PBMCs. The modulation of α1 and ÎČ3 GABA A receptors subunits expression in PBMCs may be associated with ongoing or past HCV infection
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