308 research outputs found

    Trophic relationships within intertidal communities of the Brittany Coasts: A stable carbon isotope analysis

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    More than 100 species belonging to plant and animal tars that are commonly observed in the intertidal zone were collected on both rocky and soft bottom shores of Brittany, France, to be analysed for their C-13/C-12 ratio. Plant material displayed a wide range of delta(13)C values (from -12 to -34 parts per thousand), with relatively distinct values among producer groups (Chlorophyce ae, Fucales, Laminariales, Rhodophyce ae seagrasses, plankton), and among strata of intertidal zonation. Animal delta(13)C range was narrower (-15 to -22 parts per thousand), and in general, values differed more between than within phyla or classes, according to the staple diet of organisms. A good correlation between the delta(13)C values of food and consumers was noted, together with a slight C-13- enrichment (approximate to 1 parts per thousand) with increasing trophic levels from suspension-feeders to predators

    Model-based computation of total stressed blood volume from a preload reduction manoeuvre

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    peer reviewedTotal stressed blood volume is an important parameter for both doctors and engineers. From a medical point of view, it has been associated with the success or failure of fluid therapy, a primary treatment to manage acute circulatory failure. From an engineering point of view, it dictates the cardiovascular system’s behavior in changing physiological situations. Current methods to determine this parameter involve repeated phases of circulatory arrests followed by fluid administration. In this work, a more straightforward method is developed using data from a preload reduction manoeuvre. A simple six-chamber cardiovascular system model is used and its parameters are adjusted to pig experimental data. The parameter adjustment process has three steps: (1) compute nominal values for all model parameters; (2) determine the five most sensitive parameters; and (3) adjust only these five parameters. Stressed blood volume was selected by the algorithm, which emphasizes the importance of this parameter. The model was able to track experimental trends with a maximal root mean squared error of 29.2%. Computed stressed blood volume equals 486 ± 117 ml or 15.7 ± 3.6 ml/kg, which matches previous independent experiments on pigs, dogs and humans. The method proposed in this work thus provides a simple way to compute total stressed blood volume from usual hemodynamic data

    Parameter Identification Methods in a Model of the Cardiovascular System

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    To be clinically relevant, mathematical models have to be patient-specific, meaning that their parameters have to be identified from patient data. To achieve real time monitoring, it is important to select the best parameter identification method, in terms of speed, efficiency and reliability. This work presents a comparison of seven parameter identification methods applied to a lumped-parameter cardiovascular system model. The seven methods are tested using in silico and experimental reference data. To do so, precise formulae for initial parameter values first had to be developed. The test results indicate that the trust-region reflective method seems to be the best method for the present model. This method (and the proportional method) are able to perform parameter identification in two to three minutes, and will thus benefit cardiac and vascular monitoring applications

    Amplitude equations for Rayleigh-Benard convective rolls far from threshold

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    An extension of the amplitude method is proposed. An iterative algorithm is developed to build an amplitude equation model that is shown to provide precise quantitative results even far from the linear instability threshold. The method is applied to the study of stationary Rayleigh-Benard thermoconvective rolls in the nonlinear regime. In particular, the generation of second and third spatial harmonics is analyzed. Comparison with experimental results and direct numerical calculations is also made and a very good agreement is found.Peer reviewe
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