37 research outputs found

    Etat actuel de la question de la propagation des rouilles

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    Beauverie J. Etat actuel de la question de la propagation des rouilles. In: Annales de la Société botanique de Lyon, tome 36, Notes et Mémoires - Comptes-rendus des séances – 1911. 1912. pp. 25-60

    Charles Nodier naturaliste, d'après M. le Dr Ant. Magnin

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    Beauverie J. Charles Nodier naturaliste, d'après M. le Dr Ant. Magnin. In: Annales de la Société botanique de Lyon, tome 36, Notes et Mémoires - Comptes-rendus des séances – 1911. 1912. pp. 1-8

    Fineza e comprimento de fibra de doze variedades de rami Fineness and length of fiber of twelve ramie varieties

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    Estudaram-se a fineza e o comprimento de fibra de doze variedades internacionais de rami (Boehmeria nivea Gaud.) pertencentes à coleção existente no Instituto Agronômico do Estado de São Paulo. A variedade Taiwan Hakushi destacou-se como produtora de fibras mais finas, enquanto a Hsi-Ching-Chin-Hsin foi a que apresentou fibras mais grossas. Com relação ao comprimento de fibra, as variedades P.I. 87.521, Ban-methuot e Taiwan Hakushi tiveram os valores mais baixos, apresentando porcentagens mais elevadas de fibras curtas, e Hakuhi Ibgou, Hsi-Ching-Chin-Hsin e Shalien n.° 1 apresentaram comprimentos médios de fibras mais altos, destacando-se por porcentagens mais elevadas de fibras longas.<br>A study concerning the fineness and length of the following international varieties of ramie (Boehmeria nivea Gaud.) is reported: Hakuhi Ibgou; White Skin; Taiwan Hakushi; Shalien n.° 1; Hsi-Ching-Chin-Hsin; Banmethuot; Miyasaki 112; E 47-1; Murakami; P.I. 87.521; Kagisei; and Yilan n.° 1. The study was based on fibers obtained from three month old stalks of the ramie varieties produced in the State of São Paulo, Brazil. The Taiwan Hakushi exceeded the others varieties in average fineness (Nm 1786) and the Hsi-Ching-Chin-Hsin had the lower average fineness (Nm 945). The varieties P.I. 87.521, Banmethuot e Taiwan Hakushi had the lower fiber length (average of 133 mm, 141 mm and 151 mm, respectively). Hakuhi Ibgou, Hsi-Ching-Chin-Hsin and Shalien n.° 1 had the longer fibers (average of 175 mm, respectively). The fibers classified in short, median and long, showed that the varieties of high average length fiber were more uniform than varieties of low average length fiber. The results obtained may be used by the ramie industry for production of different kinds of manufactures and also by the breeders in order to establish any breeding and selection program

    Effects of chronic paroxetine treatment on dialysate serotonin in 5-HT1B receptor knockout mice

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    Abstract The role of serotonin (5-HT) 1B receptors in the mechanism of action of selective serotonin re-uptake inhibitors (SSRI) was studied by using intracerebral in vivo microdialysis in conscious, freely moving wild-type and 5-HT 1B receptor knockout (KO 5-HT 1B ) mice in order to compare the effects of chronic administration of paroxetine via osmotic minipumps (1 mg per kg per day for 14 days) on extracellular 5-HT levels ([5-HT]ext) in the medial prefrontal cortex and ventral hippocampus. Basal ext values in the medial prefrontal cortex and ventral hippocampus, 20 h after removing the minipump, were not altered by chronic paroxetine treatment in both genotypes. On day 15, in the ventral hippocampus, an acute paroxetine challenge (1 mg/kg i.p.) induced a larger increase in [5-HT]ext in saline-pretreated mutant than in wild-type mice. This difference between the two genotypes in the effect of the paroxetine challenge persisted following chronic paroxetine treatment. Conversely, in the medial prefrontal cortex, the paroxetine challenge increased [5-HT]ext similarly in saline-pretreated mice of both genotypes. Such a challenge produced a further increase in cortical [5-HT]ext compared with that in salinepretreated groups of both genotypes, but no differences were found between genotypes following chronic treatment. To avoid the interaction with raphe 5-HT 1A autoreceptors, 1 lM paroxetine was perfused locally through the dialysis probe implanted in the ventral hippocampus; similar increases in hippocampal [5-HT]ext were found in acutely or chronically treated wild-type mice. Systemic administration of the mixed 5-HT 1B/1D receptor antagonist GR 127935 (4 mg/kg) in chronically treated wildtype mice potentiated the effect of a paroxetine challenge dose on [5-HT]ext in the ventral hippocampus, whereas systemic administration of the selective 5-HT 1A receptor antagonist WAY 100635 did not. By using the zero net flux method of quantitative microdialysis in the medial prefrontal cortex and ventral hippocampus of wild-type and KO 5-HT 1B mice, we found that basal [5-HT]ext and the extraction fraction of 5-HT were similar in the medial prefrontal cortex and ventral hippocampus of both genotypes, suggesting that no compensatory response to the constitutive deletion of the 5-HT 1B receptor involving changes in 5-HT uptake capacity occurred in vivo. As steady-state brain concentrations of paroxetine at day 14 were similar in both genotypes, it is unlikely that differences in the effects of a paroxetine challenge on hippocampal [5-HT]ext are due to alterations of the drug&apos;s pharmacokinetic properties in mutants. These data suggest that there are differences between the ventral hippocampus and medial prefrontal cortex in activation of terminal 5-HT 1B autoreceptors and their role in regulating dialysate 5-HT levels. These presynaptic receptors retain their capacity to limit 5-HT release mainly in the ventral hippocampus following chronic paroxetine treatment in mice. Keywords: antidepressant drug, 5-hydroxytryptamine 1B autoreceptor, intracerebral microdialysis, knockout mice, paroxetine, selective serotonin re-uptake inhibitor
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