Evaluation of the Biological Activity of Naturally Occurring 5,8-Dihydroxycoumarin

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Differentiation of Viburnum accessions according to their molecular, biochemical, genotoxic and microbiological features of importance to selection

In recent decades, Viburnum has been given special attention as raw material in medicine and as a food-supplementing product in the horticulture of different countries with temperate climate. The present study aimed at evaluating Viburnum varietetus using molecular markers, relates the SSR data to biochemical ones, as well as assessing the genotoxicity and antimicrobial effect of fruit juices of the species that have been selected. On the basis of the diagram of the microsatellite data, different relations between detected antocyanins and the total amount of phenols in the fruit of different accessions were discovered. In the evaluation of genotoxicity with the help of the Ames test, Viburnum accessions showed negative results. As such lyophilised juices of Viburnum fruit were not genotoxic. The results of bioassays showed that juices of different Viburnum accessions displayed bactericidal and bacteriostatic activity against all bacteria and yeast that were studied. When the juices of Viburnum berries were investigated, no inhibitory effect on microscopic fungi was foundBiologijos katedraBotanikos sodasGamtos mokslų fakultetasGamtos tyrimų centrasLietuvos agrarinių ir miškų mokslų centras, [email protected] universitetasVytauto Didžiojo universiteta