Shifting Europe's Boundaries: mass media, public opinion and the enlargement of the EU

This article demonstrates that public attitudes towards EU enlargement are strongly affected by exposure to the mass media. It reveals `priming' effects by showing that media exposure affects the standards by which individuals evaluate the accession of potential candidate countries. To gain a more refined understanding about media effects on enlargement attitudes, we analytically separate three different factors that underlie EU enlargement support for a given candidate country: its economic performance, its state of democracy and its perceived cultural `match' with the EU. Employing an experimental design, we probe the media-induced effects of these factors on EU enlargement attitudes

Rote Liste und Artenverzeichnis der Köcherfliegen Baden-Württembergs

Die vorliegende Rote Liste sowie das Artenverzeichnis der Köcherfliegen (Trichoptera) Baden-Württembergs basieren im Wesentlichen auf den Ergebnissen einer seit 1993 im Auftrag der Landesanstalt für Umweltschutz Baden-Württemberg durchgeführten landesweiten Erfassung der Köcherfliegenfauna sowie einer umfangreichen Literaturrecherche. Die Einstufung in die Gefährdungskategorien der Roten Liste ist damit das Resultat einer Bewertung der Bestandssituation der in Baden-Württemberg vorkommenden Köcherfliegenarten

Tailored negativity. Campaign consultants, candidate personality, and attack politics

To what extent are negative election campaigns “tailored” to the personality of the candidates? And with what electoral consequences? In this article we tackle these questions by focusing on the 2019 Swiss federal election. We estimate the presence of negativity as a function of the personality profile of competing candidates (Big Five) and the presence of professional consultants. Analyses based on data from a candidate survey (Selects 2019) suggest that campaign consultants are likely to take stock of the character of their candidate, and tailor the content of their campaigns accordingly - more aggressive for more energetic candidates (higher plasticity) and for less stable candidates (lower stability). These results, we argue, support our central claim that the role of consultants is to provide the most adequate campaign for the candidate they are promoting (“tailoring hypothesis”). We fail however to find any convincing evidence that such tailoring is electorally successful

Who are the ‘dark’ politicians? Insights from self-reports of German state parliament candidates

A growing body of studies is focusing on politicians' personalities, as the personality of political elites has been shown to affect their behavior. Whereas most research uses the big five framework or HEXACO, only a few studies have been able to capture more "aversive," "dark" - yet non-pathological - personality traits of politicians. However, these studies refer to top politicians; information on the distribution and the correlates of dark personality traits in the broad mass of politicians is still lacking. Moreover, information on dark personality traits in politicians is usually based on expert ratings; data using self-placement is missing. Based on data from six surveys with candidates running for German state elections in 2021 and 2022 (N[pooled data set] = 1,632), we, to the best of our knowledge, offer, for the first time, insights into politicians’ self-reported socially aversive personality traits. "Dark" personality traits are measured by the political elites aversive personality scale (PEAPS). Results show that German politicians exhibit moderate levels of aversive personality traits. In addition, the extent of candidates' dark personalities is strongly negatively correlated with honesty-humility, agreeableness vs. anger, and extraversion, while associations with other basic personality traits are much weaker or insignificant. We also find that younger, more right-leaning, and more ideologically extreme candidates report higher levels of aversive personality

Debating Europe: Effects of the "Eurovision Debate" on EU Attitudes of Young German Voters and the Moderating Role Played by Political Involvement

In the run-up to the elections to the European Parliament in 2014, EU citizens had the unprecedented opportunity to watch televised debates between the candidates running for president of the European Commission. The most important debate was the so-called "Eurovision debate", which was broadcasted in almost all EU member states. In this study we explore the responses of a sample of 110 young German voters, who watched this debate, to the candidates' messages and whether exposure to the debate caused a shift in the respondents' attitudes towards the EU. Combining data from a quasi-experiment, real-time response data, and data from a content analysis of the debate, we find that respondents' reactions to the candidates' statements were-on average-positive and that some respondents displayed attitudinal changes resulting in more favorable views towards the EU. Although the direct connection between real-time responses and post-debate attitudes is not as strong as expected, most of the measured effects indicate that a positive evaluation of the candidates' messages usually results in more pro-European attitudes. Furthermore, we find no strong evidence that political knowledge moderates debate effects. In general, differences between political 'novices' and political 'experts' tend to be rare

Sulindac sulfide reverses aberrant self-renewal of progenitor cells induced by the AML-associated fusion proteins PML/RARalpha and PLZF/RARalpha

Chromosomal translocations can lead to the formation of chimeric genes encoding fusion proteins such as PML/RARalpha, PLZF/RARalpha, and AML-1/ETO, which are able to induce and maintain acute myeloid leukemia (AML). One key mechanism in leukemogenesis is increased self renewal of leukemic stem cells via aberrant activation of the Wnt signaling pathway. Either X-RAR, PML/RARalpha and PLZF/RARalpha or AML-1/ETO activate Wnt signaling by upregulating gamma-catenin and beta-catenin. In a prospective study, a lower risk of leukemia was observed with aspirin use, which is consistent with numerous studies reporting an inverse association of aspirin with other cancers. Furthermore, a reduction in leukemia risk was associated with use of non-steroidal anti-inflammatory drug (NSAID), where the effects on AML risk was FAB subtype-specific. To better investigate whether NSAID treatment is effective, we used Sulindac Sulfide in X-RARalpha-positive progenitor cell models. Sulindac Sulfide (SSi) is a derivative of Sulindac, a NSAID known to inactivate Wnt signaling. We found that SSi downregulated both beta-catenin and gamma-catenin in X-RARalpha-expressing cells and reversed the leukemic phenotype by reducing stem cell capacity and increasing differentiation potential in X-RARalpha-positive HSCs. The data presented herein show that SSi inhibits the leukemic cell growth as well as hematopoietic progenitors cells (HPCs) expressing PML/RARalpha, and it indicates that Sulindac is a valid molecular therapeutic approach that should be further validated using in vivo leukemia models and in clinical settings

Perspektivlose Handelspolitik

Die gegenwärtige Handelspolitik der Europäischen Union ist geprägt von dem Ziel weiterer Marktöffnung. Um der fortschreitenden Globalisierung zu begegnen, braucht es vielmehr eine neue Balance zwischen globalen und regionalen Märkten