Quantifying long-range correlations in complex networks beyond nearest neighbors

We propose a fluctuation analysis to quantify spatial correlations in complex networks. The approach considers the sequences of degrees along shortest paths in the networks and quantifies the fluctuations in analogy to time series. In this work, the Barabasi-Albert (BA) model, the Cayley tree at the percolation transition, a fractal network model, and examples of real-world networks are studied. While the fluctuation functions for the BA model show exponential decay, in the case of the Cayley tree and the fractal network model the fluctuation functions display a power-law behavior. The fractal network model comprises long-range anti-correlations. The results suggest that the fluctuation exponent provides complementary information to the fractal dimension

Fermi acceleration and suppression of Fermi acceleration in a time-dependent Lorentz Gas

We study some dynamical properties of a Lorentz gas. We have considered both the static and time dependent boundary. For the static case we have shown that the system has a chaotic component characterized with a positive Lyapunov Exponent. For the time-dependent perturbation we describe the model using a four-dimensional nonlinear map. The behaviour of the average velocity is considered in two situations (i) non-dissipative and (ii) dissipative. Our results show that the unlimited energy growth is observed for the non-dissipative case. However, when dissipation, via damping coefficients, is introduced the senary changes and the unlimited engergy growth is suppressed. The behaviour of the average velocity is described using scaling approach

The properties of the D-meson in dense matter

We study the D-meson spectral density in dense matter within the framework of a coupled-channel self-consistent calculation taking, as bare meson-baryon interaction, a separable potential. Our coupled-channel model generates dynamically the $\Lambda_c(2593)$ resonance. The medium modifications of the D-meson properties due to Pauli blocking and the dressing of D-mesons, nucleons and pions are also discussed. We found that the coupled-channel effects in the self-consistent process reduce the in-medium effects on the D-meson compared to previous works.Comment: 4 pages, 4 figures, to appear in the proceedings of Strangeness in Quark Matter 2004 (SQM2004), Cape Town, South Africa, 15-20 September 200

Botulinum Toxin A for the Treatment of Keloids

Introduction: Keloids are the result of excessive scar tissue formation. Besides their poor aesthetic appearance, keloids can be associated with severe clinical symptoms such as pain, itching, and rigidity. Unfortunately, most therapeutic approaches remain clinically unsatisfactory. Recently, injections with botulinum toxin A (BTA) were proposed for the treatment of established keloids in a clinical trial. In this study, we aimed to verify the effects of intralesional BTA for the treatment of therapy-resistant keloids using objective measurements. In addition, the underlying molecular mechanisms were investigated using cultured keloid-derived fibroblasts. Materials and Methods: Four patients received BTA (doses varying from 70 to 140 Speywood units per session) injected directly into their keloids every 2 months for up to 6 months. Differences in height and volume were evaluated clinically and measured with a 3-D optical profiling system. Keloid-derived fibroblasts were treated with different concentrations of BTA, and expression of collagen (COL)1A1, COL1A2, COL3A1, TGF-beta 1, TGF-beta 2, TGF-beta 3, fibronectin-1, laminin-beta 2, and alpha-SMA was determined by real-time quantitative PCR. MTT and BrdU assays were used to analyze the effects of BTA on fibroblast proliferation and metabolism. Results: Intralesional administration of BTA did not result in regression of keloid tissue. No differences in expression of ECM markers, collagen synthesis, or TGF-beta could be observed after BTA treatment of keloid fibroblasts. In addition, cell proliferation and metabolism of keloid fibroblasts was not affected by BTA treatment. Conclusion: The suggested clinical efficiency of intralesional BTA for the therapy of existent keloids could not be confirmed in this study. Based on our data, the potential mechanisms of action of BTA on keloid-derived fibroblasts remain unclear. Copyright (C) 2012 S. Karger AG, Base