Занятость в эпоху технологических изменений и цифровизации экономики

Объектом исследования является современный рынок труда. Предмет исследования - занятость в эпоху технологических изменений и цифровизации экономики. Цель выпускной квалификационной работы – выявить специфику занятости в эпоху новых технологических изменений (на примере Китая). - дать характеристику занятости в эпоху технологических изменений и цифровизации экономики. - рассмотреть специфику становления рынка занятости на современном этапе развития экономики. - проанализировать состояние фриланса на европейском и российском рынке труда. В работе проведен анализ актуальных глобальных экономических и технологических тенденций, влияющих на трансформацию рынка труда и формирование новых социально-экономических отношений в условиях становления цифровой экономики.The object of research is the modern labor market. The subject of the study is employment in the era of technological change and the digitalization of the economy. The purpose of the final qualification work is to identify the specifics of employment in the era of new technological changes (for example, China). - to characterize employment in the era of technological change and the digitalization of the economy. - to consider the specifics of the formation of the employment market at the present stage of economic development. The paper analyzes the current global economic and technological trends that affect the transformation of the labor market and the formation of new socio-economic relations in the context of the digital economy

Modern Social Welfare in the Light of the Sustainability Model

The paper presents the analysis of interaction between the social welfare and sustainable development. The aim of this paper is to show that the social development mostly depends on community values that form the pathway of the social movement. It is shown that mankind can influence the future choosing the optimum way of its development. Therefore, it is necessary to appreciate personal aspects of sociogenesis and a mechanism of its functioning, differences between social and natural dynamics. From the authors’ viewpoint, a philosophical understanding of sustainability by means of welfare as a regulation mechanism, is one of approaches to the study of social life and social development. A model of socio-practical man's existence mostly oriented towards satisfaction of needs helps to analyze the relationship between the categories under review. The more so as an ordinary intake of consumer amenities transforms to the instrument of construction od social identity, the sociocultural integration of individual with society. Social welfare is presented as a multiple-factor construct represented by a synthesis of cause and effect. Explication technique, hermeneutical approach, and comparison study are used to clarify basic notions of this research

The hybridization of vocational and organizational and entrepreneurial skills in the activity of the well-being of modern society

This paper considers the problem of the need to transform approaches to organization, business, economic processes and education. The functional dependence between business and social well-being of society is revealed. The relevance of social aspects of entrepreneurial activity is emphasized. Currently, entrepreneurship is seen not only as a process of making a profit, but also as innovation, creativity, generation of ideas and non-standard approaches to activity. In this context, the skills of the entrepreneur acquire a special meaning and are important for specialists in various fields. Entrepreneurship can and should be considered by the organizers of education as a unique opportunity for the integration preparation of students for the implementation of professional - organizational and entrepreneurial activities at the same time. The concept of "hybrid activity" is introduced and the definition of "entrepreneurial skills" for a University student is proposed

Bericht des Nationalen Referenzzentrums für gramnegative Krankenhauserreger

Im Zeitraum vom 1. Januar 2022 bis zum 31. Dezember 2022 gab es im Nationalen Referenzzentrum (NRZ) für gramnegative Krankenhauserreger 9.548 Einsendungen von Bakterienisolaten. Dies entspricht einem Anstieg von fast 12 % im Vergleich zu 2021 und übertrifft das Vor-Pandemieniveau von 2019 (n = 9.369). Die Anzahl der Einsendungen lag bei durchschnittlich 796 Einsendungen pro Monat, die Isolate stammten aus 301 mikrobiologischen Laboren in Deutschland. Die Zahl der einsendenden Labore nahm im Vergleich zum Vorjahr (n = 283) ebenfalls zu. Wie das Epidemiologische Bulletin 27/2023 ausführt, stieg zudem Die Anzahl der Carbapenemase-Nachweise bei den bearbeiteten Isolaten stieg zudem auf den höchsten jemals im NRZ beobachteten Anstieg.Peer Reviewe

Entdeckung eines Pseudoausbruches mit Carbapenem-resistenten Acinetobacter baumannii

Am Nationalen Referenzzentrum für gramnegative Krankenhauserreger wurde im November und Dezember 2020 das gehäufte Auftreten von Isolaten des Acinetobacter baumannii-Komplex mit Carbapenemresistenz beobachtet. Der Beitrag beschreibt die in Kooperation mit dem Robert Koch-Institut durchgeführte Ausbruchsuntersuchung und die Aufklärung als Pseudoausbruch.Peer Reviewe

Expression profile of the transient receptor potential (TRP) family in neutrophil granulocytes: evidence for currents through long TRP channel 2 induced by ADP-ribose and NAD

An early key event in the activation of neutrophil granulocytes is Ca(2+) influx. Members of the transient receptor potential (TRP) channel family may be held responsible for this. The aim of the present study is to analyse the expression pattern of TRP mRNA and identify characteristic currents unambiguously attributable to particular TRP channels. mRNA was extracted from human neutrophils, isolated by gradient centrifugation and also by magnetically labelled CD15 antibodies. The presence of mRNA was demonstrated using reverse transcriptase-PCR in neutrophils (controlled to be CD5-negative) as well as in human leukaemic cell line 60 (HL-60) cells, for the following TRP species: the long TRPC2 (LTRPC2), the vanilloid receptor 1, the vanilloid receptor-like protein 1 and epithelial Ca(2+) channels 1 and 2. TRPC6 was specific for neutrophils, whereas only in HL-60 cells were TRPC1, TRPC2, TRPC3, melastatin 1 and melastatin-related 1 found. Patch-clamp measurements in neutrophils revealed non-selective cation currents evoked by intracellular ADP-ribose and by NAD(+). Both these modes of activation have been found to be characteristic of LTRPC2. Furthermore, single-channel activity was resolved in neutrophils and it was indistinguishable from that in LTRPC2-transfected HEK-293 cells. The results provide evidence that LTRPC2 in neutrophil granulocytes forms an entry pathway for Na(+) and Ca(2+), which is regulated by ADP-ribose and the redox state