1,333 research outputs found
Random field spin models beyond one loop: a mechanism for decreasing the lower critical dimension
The functional RG for the random field and random anisotropy O(N)
sigma-models is studied to two loop. The ferromagnetic/disordered (F/D)
transition fixed point is found to next order in d=4+epsilon for N > N_c
(N_c=2.8347408 for random field, N_c=9.44121 for random anisotropy). For N <
N_c the lower critical dimension plunges below d=4: we find two fixed points,
one describing the quasi-ordered phase, the other is novel and describes the
F/D transition. The lower critical dimension can be obtained in an
(N_c-N)-expansion. The theory is also analyzed at large N and a glassy regime
is found.Comment: 4 pages, 5 figure
T-cell modulation for the treatment of chronic plaque psoriasis with efalizumab (Raptiva (TM)): Mechanisms of action
Psoriasis is a chronic, incurable, auto-immune disorder with cutaneous manifestations. New evidence on the central role of the immune system in the pathogenesis of psoriasis increasingly provides insight into pathogenic steps that can be modulated to provide disease control. Numerous biological therapies are in various stages of clinical development, with expectation of providing enhanced safety and efficacy over currently available psoriasis therapies. Efalizumab, a recombinant humanized monoclonal IgG1 antibody, is a novel targeted T-cell modulator that inhibits multiple steps in the immune cascade that result in the production and maintenance of psoriatic plaques, including initial T-cell activation and T-cell trafficking into sites of inflammation, including psoriatic skin, with subsequent reactivation in these sites. This article reviews the pharmacodynamic, pharmacokinetic and clinical effects observed during phase I, II and III efalizumab trials in patients with moderate to severe chronic plaque psoriasis. Copyright (C) 2004 S. Karger AG, Basel
Statistical Mechanics of Community Detection
Starting from a general \textit{ansatz}, we show how community detection can
be interpreted as finding the ground state of an infinite range spin glass. Our
approach applies to weighted and directed networks alike. It contains the
\textit{at hoc} introduced quality function from \cite{ReichardtPRL} and the
modularity as defined by Newman and Girvan \cite{Girvan03} as special
cases. The community structure of the network is interpreted as the spin
configuration that minimizes the energy of the spin glass with the spin states
being the community indices. We elucidate the properties of the ground state
configuration to give a concise definition of communities as cohesive subgroups
in networks that is adaptive to the specific class of network under study.
Further we show, how hierarchies and overlap in the community structure can be
detected. Computationally effective local update rules for optimization
procedures to find the ground state are given. We show how the \textit{ansatz}
may be used to discover the community around a given node without detecting all
communities in the full network and we give benchmarks for the performance of
this extension. Finally, we give expectation values for the modularity of
random graphs, which can be used in the assessment of statistical significance
of community structure
Numerical treatment of the hyperboloidal initial value problem for the vacuum Einstein equations. III. On the determination of radiation
We discuss the issue of radiation extraction in asymptotically flat
space-times within the framework of conformal methods for numerical relativity.
Our aim is to show that there exists a well defined and accurate extraction
procedure which mimics the physical measurement process. It operates entirely
intrisically within \scri^+ so that there is no further approximation
necessary apart from the basic assumption that the arena be an asymptotically
flat space-time. We define the notion of a detector at infinity by idealising
local observers in Minkowski space. A detailed discussion is presented for
Maxwell fields and the generalisation to linearised and full gravity is
performed by way of the similar structure of the asymptotic fields.Comment: LaTeX2e,13 pages,2 figure
Hydrogen atom in crossed electric and magnetic fields: Phase space topology and torus quantization via periodic orbits
A hierarchical ordering is demonstrated for the periodic orbits in a strongly
coupled multidimensional Hamiltonian system, namely the hydrogen atom in
crossed electric and magnetic fields. It mirrors the hierarchy of broken
resonant tori and thereby allows one to characterize the periodic orbits by a
set of winding numbers. With this knowledge, we construct the action variables
as functions of the frequency ratios and carry out a semiclassical torus
quantization. The semiclassical energy levels thus obtained agree well with
exact quantum calculations
Partitioning and modularity of graphs with arbitrary degree distribution
We solve the graph bi-partitioning problem in dense graphs with arbitrary
degree distribution using the replica method. We find the cut-size to scale
universally with . In contrast, earlier results studying the problem in
graphs with a Poissonian degree distribution had found a scaling with ^1/2
[Fu and Anderson, J. Phys. A: Math. Gen. 19, 1986]. The new results also
generalize to the problem of q-partitioning. They can be used to find the
expected modularity Q [Newman and Grivan, Phys. Rev. E, 69, 2004] of random
graphs and allow for the assessment of statistical significance of the output
of community detection algorithms.Comment: Revised version including new plots and improved discussion of some
mathematical detail
Approaching the Ground State of Frustrated A-site Spinels: A Combined Magnetization and Polarized Neutron Scattering Study
We re-investigate the magnetically frustrated, {\it
diamond-lattice-antiferromagnet} spinels FeAlO and MnAlO using
magnetization measurements and diffuse scattering of polarized neutrons. In
FeAlO, macroscopic measurements evidence a "cusp" in zero field-cooled
susceptibility around 13~K. Dynamic magnetic susceptibility and {\it memory
effect} experiments provide results that do not conform with a canonical
spin-glass scenario in this material. Through polarized neutron scattering
studies, absence of long-range magnetic order down to 4~K is confirmed in
FeAlO. By modeling the powder averaged differential magnetic neutron
scattering cross-section, we estimate that the spin-spin correlations in this
compound extend up to the third nearest-neighbour shell. The estimated value of
the Land\'{e} factor points towards orbital contributions from Fe.
This is also supported by a Curie-Weiss analysis of the magnetic
susceptibility. MnAlO, on the contrary, undergoes a magnetic phase
transition into a long-range ordered state below 40~K, which is
confirmed by macroscopic measurements and polarized neutron diffraction.
However, the polarized neutron studies reveal the existence of prominent
spin-fluctuations co-existing with long-range antiferromagnetic order. The
magnetic diffuse intensity suggests a similar short range order as in
FeAlO. Results of the present work supports the importance of spin-spin
correlations in understanding magnetic response of frustrated magnets like
-site spinels which have predominant short-range spin correlations
reminiscent of the "spin liquid" state.Comment: 10 pages, 10 figures, double-column, accepted in Phys. Rev. B, 201
Electronic Structure of Atoms in Magnetic Quadrupole Traps
We investigate the electronic structure and properties of atoms exposed to a
magnetic quadrupole field. The spin-spatial as well as generalized time
reversal symmetries are established and shown to lead to a two-fold degeneracy
of the electronic states in the presence of the field. Low-lying as well as
highly excited Rydberg states are computed and analyzed for a broad regime of
field gradients. The delicate interplay between the Coulomb and various
magnetic interactions leads to complex patterns of the spatial spin
polarization of individual excited states. Electromagnetic transitions in the
quadrupole field are studied in detail thereby providing the selection rules
and in particular the transition wavelengths and corresponding dipole
strengths. The peculiar property that the quadrupole magnetic field induces
permanent electric dipole moments of the atoms is derived and discussed.Comment: 17 pages, 13 figures, accepted for publication in PR
Surmounting Oscillating Barriers
Thermally activated escape over a potential barrier in the presence of
periodic driving is considered. By means of novel time-dependent path-integral
methods we derive asymptotically exact weak-noise expressions for both the
instantaneous and the time-averaged escape rate. The agreement with accurate
numerical results is excellent over a wide range of driving strengths and
driving frequencies.Comment: 4 pages, 4 figure
Fermi surface of MoO2 studied by angle-resolved photoemission spectroscopy, de Haas-van Alphen measurements, and electronic structure calculations
A comprehensive study of the electronic properties of monoclinic MoO2 from
both an experimental and a theoretical point of view is presented. We focus on
the investigation of the Fermi body and the band structure using angle resolved
photoemission spectroscopy, de Haas-van Alphen measurements, and electronic
structure calculations. For the latter, the new full-potential augmented
spherical wave (ASW) method has been applied. Very good agreement between the
experimental and theoretical results is found. In particular, all Fermi surface
sheets are correctly identified by all three approaches. Previous controversies
concerning additional hole-like surfaces centered around the Z- and B-point
could be resolved; these surfaces were an artefact of the atomic-sphere
approximation used in the old calculations. Our results underline the
importance of electronic structure calculations for the understanding of MoO2
and the neighbouring rutile-type early transition-metal dioxides. This includes
the low-temperature insulating phases of VO2 and NbO2, which have crystal
structures very similar to that of molybdenum dioxide and display the
well-known prominent metal-insulator transitions.Comment: 17 pages, 21 figures, more information at
http://www.physik.uni-augsburg.de/~eyert
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