Correction: Inflammation in Sickle Cell Disease: Differential and Down-Expressed Plasma Levels of Annexin A1 Protein.

[This corrects the article DOI: 10.1371/journal.pone.0165833.]

Characterization of the study groups.

<p>Characterization of the study groups.</p

Plasma levels of the proinflammatory cytokines in the control and SCD groups.

<p>(A) IL-1β. (B) IL-8. (C) TNF-α. Data expressed in mean ± standard error of the mean. Statistical analysis: Student t-test. *p < 0.05. **p < 0.01. ***p < 0.001.</p

Plasma levels of ANXA1 in control and SCD groups.

<p>Data expressed in mean ± standard error of the mean. Statistical analysis: <i>Student’s t-test</i>. *p<0.05.</p

Hematological profile of the SCD genotypes.

<p>Hematological profile of the SCD genotypes.</p

Correlation between plasma levels of ANXA1 and the count of WBC and platelets in SCD patients.

<p>(A) ANXA1 <i>versus</i> WBC. (B) ANXA1 <i>versus</i> Platelets. WBC: white blood cells. Statistical analysis: Pearson’s correlation. Data expressed in logarithm. Moderate correlation between ANXA1 and WBC: r = 0.31; p = 0.03. Moderate correlation between ANXA1 and platelets: r = 0.42; p = 0.01.</p

Hemolytic status in the SCD genotypes.

<p>(A) Reticulocytes. (B) LDH. (C) AST. (D) UCB. LDH: lactate dehydrogenase. AST: aspartate aminotransferase. UCB: unconjugated bilirubin. U/L: unit per liter. mm/dL: millimeter per deciliter. Reference values: Reticulocytes (1.0–2.6%); LDH (< 480 U/L); AST (< 31 U/L); UCB (< 0.7 mm/dL). Statistical analysis: <i>Kruskal-Wallis</i> followed by <i>Dunn’s</i> test for A and B; <i>one-way ANOVA</i> followed by <i>Tukey’s</i> test for C and D. *p < 0.05. ***p < 0.001.</p

Plasma levels of ANXA1 in control group and SCD genotypes.

<p>Data expressed in mean ± standard error of the mean. Statistical analysis: <i>one-way ANOVA</i>. *p<0.05 for <i>Tukey-Krumer post hoc</i>. ^#p<0.05 for <i>Dunnett’s post hoc</i>.</p