MANOVA exploring the effect of treatments and age on the morphology of sperm collected in the epididymis and the testes.

<p>Age: 3 vs 17 months. The dependent variables were the teratozoospermia index and the proportion of sperm with single and multiple morphological abnormalities.</p

Effect of the LPS treatment on the production of plasmatic serum amyloid A.

<p>The bars represent the mean ± SE.</p

Effect of the anti-IL-10R treatment on the production of plasmatic serum amyloid A.

<p>The bars represent the mean ± SE.</p

Generalized linear mixed model reporting the effect of the experimental treatments and age on the temporal variation (day 0, and 8) in the plasma concentration of the serum amyloid A.

<p>Body mass at day 0 and 8 was also included as a covariate in the model. Mouse identity was fitted into the model as a random factor as to take into account the repeated nature of the data.</p

Change in body mass (g) during the course of the experiment for young (3 month old) and old (17 month old) male mice.

<p>We report means with standard errors.</p

Change in body mass (g) during the course of the experiment for male mice according to the four experimental treatments.

<p>We report means with standard errors.</p

Mixed linear model exploring the effect of the treatments and age on the changes in body mass over the nine days of the experiment.

<p>Age: 3 vs 17 months. Individual identity was declared as a random factor.</p

Log-linear model reporting the effect of the experimental treatments and body mass variation (percent variation in body mass between day 0 and day 2) on the survival rate of 15 months old mice.

<p>Log-linear model reporting the effect of the experimental treatments and body mass variation (percent variation in body mass between day 0 and day 2) on the survival rate of 15 months old mice.</p

Morphology sperm collected in the testes of young and old mice according to the different experimental groups.

<p>We report means ± SE, n = 5 mice per group. Young = 3 month old; Old = 17 month old. TZI: teratozoospermia index.</p

Teratozoospermia index for mice injected with LPS or PBS.

<p>We report means with standard errors.</p