QCD Corrections to Vector-Boson Fusion Processes in Warped Higgsless Models

We discuss the signatures of a representative Higgsless model with ideal fermion delocalization in vector-boson fusion processes, focusing on the gold- and silver-plated decay modes of the gauge bosons at the CERN-Large Hadron Collider. For this purpose, we have developed a fully-flexible parton-level Monte-Carlo program, which allows for the calculation of cross sections and kinematic distributions within experimentally feasible selection cuts at NLO-QCD accuracy. We find that Kaluza-Klein resonances give rise to very distinctive distributions of the decay leptons. Similar to the Standard Model case, within the Higgsless scenario the perturbative treatment of the vector-boson scattering processes is under excellent control.Comment: 22 pages, 20 figure

Internal kinematics of spiral galaxies in distant clusters III. Velocity fields from FORS2/MXU spectroscopy

(Abridged) We study the impact of cluster environment on the evolution of spiral galaxies by examining their structure and kinematics. Rather than two-dimensional rotation curves, we observe complete velocity fields by placing three adjacent and parallel FORS2 MXU slits on each object, yielding several emission and absorption lines. The gas velocity fields are reconstructed and decomposed into circular rotation and irregular motions using kinemetry. To quantify irregularities in the gas kinematics, we define three parameters: sigma_{PA} (standard deviation of the kinematic position angle), Delta phi (the average misalignment between kinematic and photometric position angles) and k_{3,5} (squared sum of the higher order Fourier terms). Using local, undistorted galaxies from SINGS, these can be used to establish the regularity of the gas velocity fields. Here we present the analysis of 22 distant galaxies in the MS0451.6-0305 field with 11 members at z=0.54. In this sample we find both field (4 out of 8) and cluster (3 out of 4) galaxies with velocity fields that are both irregular and asymmetric. We show that these fractions are underestimates of the actual number of galaxies with irregular velocity fields. The values of the (ir)regularity parameters for cluster galaxies are not very different from those of the field galaxies, implying that there are isolated field galaxies that are as distorted as the cluster members. None of the deviations in our small sample correlate with photometric/structural properties like luminosity or disk scale length in a significant way. Our 3D-spectroscopic method successfully maps the velocity field of distant galaxies, enabling the importance and efficiency of cluster specific interactions to be assessed quantitatively.Comment: accepted for publication in A&A, high resolution version available at http://www.astro.rug.nl/~kutdemir/papers

Physiological Reflux and Venous Diameter Change in the Proximal Lower Limb Veins During a Standardised Valsalva Manoeuvre

AbstractObjectives: the aim of this study was to provide normal values for venous diameter at rest, and venous diameter and physiologic venous reflux during a standardised Valsalva manoeuvre. The impact of the patient's sex, body mass index (BMI), and family history was investigated. Material and methods: eighty legs of 40 healthy volunteers were investigated in a supine position. The median age was 28 years (range 20–66 years). The common femoral vein (CFV), the proximal superficial femoral vein (SFV) and the proximal long saphenous vein (LSV) were investigated by duplex sonography. The following parameters were assessed: resting diameter (VDrest) and maximum diameter (VDmax) as well as reflux time (tr) during the Valsalva manoeuvre. The Valsalva manoeuvre was elicited by a forceful expiration into a tube system. The standard values used were a pressure of 30 mmHg, established within 0.5 seconds (s) and maintained over a time period of at least 3 s. Results: mean VDrestand VDmaxwere 8.3±2.2 and 11.1±2.8 mm in the CFV, 5.9±1.3 and 7.2±1.6 mm in the SFV and 3.5±0.9 and 4.3±1.4 mm in the LSV. Mean values for trwere 0.61±0.63 s in the CFV, 0.25±0.26 s in the SFV and 0.28±0.40 s in the LSV. A BMI >22.5 kg/m2was associated with statistically significant larger values for VDrestand tr. If adjusted for BMI, trin the SFV and the LSV did not differ by sex. For healthy subjects with first-degree relatives suffering from varicose veins (n=19), mean VDrestin the SFV as well as VD in the LSV was significantly larger (p=0.02, 0.05, respectively). Coefficients of variation for repeated measurements (VDrest, VDmax, tr) in the same segment varied between 3.3% and 16.4% for the three investigated sites.Conclusions: normal values for VDrestand VDmaxas well as reflux time during a standardised Valsalva manouevre were assessed in the proximal lower limb veins. The influences of BMI, sex and family history were investigated. The described standardised Valsalva manoeuvre led to highly reproducible results and can be recommended for further research projects or as a routine procedure for the assessment of venous reflux

Revealing solvent-dependent folding behaviour of mycolic acids from Mycobacterium tuberculosis by advanced simulation analysis

Mycobacterium tuberculosis remains a persistent pathogen, partly due to its lipid rich cell wall, of which mycolic acids (MAs) are a major component. The fluidity and conformational flexibilities of different MAs in the bacterial cell wall significantly influence its properties, function, and observed pathogenicity; thus, a proper conformational description of different MAs in different environments (e.g., in vacuum, in solution, in monolayers) can inform about their potential role in the complex setup of the bacterial cell wall. Previously, we have shown that molecular dynamics (MD) simulations of MA folding in vacuo can be used to characterize MA conformers in seven groupings relating to bending at the functional groups (W, U and Z-conformations). Providing a new OPLS-based forcefield parameterization for the critical cyclopropyl group of MAs and extensive simulations in explicit solvents (TIP4P water, hexane), we now present a more complete picture of MA folding properties together with improved simulation analysis techniques. We show that the ‘WUZ’ distance-based analysis can be used to pinpoint conformers with hairpin bends at the functional groups, with these conformers constituting only a fraction of accessible conformations. Applying principle component analysis (PCA) and refinement using free energy landscapes (FELs), we are able to discriminate a complete and unique set of conformational preferences for representative alpha-, methoxy- and keto-MAs, with overall preference for folded conformations. A control backbone-MA without any mero-chain functional groups showed significantly less folding in the mero-chain, confirming the role of functionalization in directing folding. Keto-MA showed the highest percentage of WUZ-type conformations and, in particular, a tendency to fold at its alpha-methyl trans-cyclopropane group, in agreement with results from Villeneuve et al. MAs demonstrate similar folding in vacuum and water, with a majority of folded conformations around the W-conformation, although the molecules are more flexible in vacuum than in water. Exchange between conformations, with a disperse distribution that includes unfolded conformers, is common in hexane for all MAs, although with more organization for Keto-MA. Globular, folded conformations are newly defined and may be specifically relevant in biofilms

Precision Calculations for Future Colliders

I discuss the motivations for, and the status of, precision calculations for the Large Hadron Collider (LHC) and the planned International Linear Collider (ILC).Comment: latex, uses ws-ijmpe.cls, 19 pages, 9 figures, 1 table, based on a talk given at the symposium "50 Years of High Energy Physics at UB", to appear in International Journal of Modern Physics