1,006 research outputs found
Photoabsorption spectra in the continuum of molecules and atomic clusters
We present linear response theories in the continuum capable of describing
photoionization spectra and dynamic polarizabilities of finite systems with no
spatial symmetry. Our formulations are based on the time-dependent local
density approximation with uniform grid representation in the three-dimensional
Cartesian coordinate. Effects of the continuum are taken into account either
with a Green's function method or with a complex absorbing potential in a
real-time method. The two methods are applied to a negatively charged cluster
in the spherical jellium model and to some small molecules (silane, acetylene
and ethylene).Comment: 13 pages, 9 figure
A depth averaged model of open channel flows with a horseshoe vortex
River engineeringNumerical modelling in river engineerin
Napsin A and Thyroid Transcription Factor-1-Positive Cerebellar Tumor with Epidermal Growth Factor Receptor Mutation
We present a very rare case of cerebellar metastasis of unknown origin, in which a primary lung adenocarcinoma was diagnosed by pathological examination of a cerebellar metastatic tumor, using immunohistochemical markers and epidermal growth factor receptor (EGFR) mutation of primary lung cancer. A 69-year-old woman was admitted to our hospital because of a hemorrhagic cerebellar tumor and multiple small brain tumors. She underwent cerebellar tumor resection. On pathological examination, the tumor was diagnosed as adenocarcinoma. However, the primary tumor site was unidentifiable even with several imaging inspections. On immunohistochemical analysis, the resected tumor was positive for napsin A and thyroid transcription factor-1. In addition, an EGFR mutation was detected in the tumor. Therefore, primary lung cancer was diagnosed and the patient was started on gefitinib (250 mg/day) therapy
The Role of Cytokine in the Lupus Nephritis
Lupus nephritis (LN)
is a major clinical manifestation of systemic
lupus erythematosus (SLE). Although numerous
abnormalities of immune system have been
proposed, cytokine overexpression plays an
essential role in the pathogenesis of LN. In the
initial phase of the disease, the
immune deposits and/or autoantibodies induce
cytokine production in renal resident cells,
leading to further inflammatory
cytokine/chemokine expression and leukocyte
infiltration and activation. Then, infiltrate
leukocytes, such as macrophages (Mφ) and dendritic cells (DCs), secrete a variety of
cytokines and activate naïve T cells, leading the cytokine
profile towards T helper (Th)1, Th2, and/or Th17. Recent studies
revealed these inflammatory processes in experimental animal
models as well as human LN. The cytokine targeted intervention may
have the therapeutic potentials for LN. This paper focuses on the
expression of cytokine and its functional role in the pathogenesis
of LN
生体の電位測定とその映像化に関する研究
金沢大学医学部研究課題/領域番号:X00090----357409研究期間(年度):1978出典:「生体の電位測定とその映像化に関する研究」研究成果報告書 課題番号X00090----357409(KAKEN:科学研究費助成事業データベース(国立情報学研究所)) (https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-X00090----357409/)を加工して作
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