On the clinical pharmacology of isoniazid (Literature survey)

Data of a comparative assessment of procedures for isoniazid phenotyping and acetylation as well as the significance of the nature of its metabolism in treating tuberculosis, and contemporary concepts as to the causes underlying the individual hepatotoxicity of the drug are discussed

On the clinical pharmacology of isoniazid (Literature survey)

Data of a comparative assessment of procedures for isoniazid phenotyping and acetylation as well as the significance of the nature of its metabolism in treating tuberculosis, and contemporary concepts as to the causes underlying the individual hepatotoxicity of the drug are discussed

Effect of calcium channel blockers on human platelet aggregation induced by agonists of alpha-adrenoreceptors

[No abstract available

The effect of nonspanum, halidor, dibazol and euphylline on the fibrinogen content and fibrinolytic acitivity of the blood (Russian)

[No abstract available

Ramipril against hypertension: Pharmacodynamic validation of efficacy in primary lesions of the heart and kidneys

[No abstract available

The effect of nonspanum, halidor, dibazol and euphylline on the fibrinogen content and fibrinolytic acitivity of the blood (Russian)

[No abstract available

Ramipril against hypertension: Pharmacodynamic validation of efficacy in primary lesions of the heart and kidneys

[No abstract available

Effect of calcium channel blockers on human platelet aggregation induced by agonists of alpha-adrenoreceptors

[No abstract available

Effect of nifedipine on hemodynamic parameters and cerebral circulation in hypertensive patients

[No abstract available

Regression of structural and functional alterations in the hypertrophic left ventricle as a result of a long-term correction of arterial pressure with ingibeis (chilasapril)

The regression of structural and functional alterations in the hypertrophic left ventricle was measured in the course of long-term correction of arterial pressure with a new inhibitor of angiotensin-converting enzyme ingibeis (chilasapril) in 23 patients with essential hypertension stage II-III. The results were for the most part obtained at echocardiography providing basic hemodynamic parameters and those of left ventricular diastolic function. Adaptability of the hypertrophic myocardium in response to physical loading was studied dynamically under isometric exercise test. The findings proved high efficacy of chilasapril in monotherapy of arterial hypertension. Long-term (6 months) therapy of left, ventricular hypertrophy provides regression of the latter and improves left ventricular diastolic function, pumping capacity. In the course of arterial hypertension correction relevant patients with associated coronary heart disease improved their condition, demonstrated less frequent ECG changes indicative of ischemia