Geographic distribution of patients.

<p>Locations of patients included in the individual patient data meta-analysis. The number indicates the number of participants included from each location.</p

Proportion of patients achieving successful treatment outcomes, stratified by method of diagnosis, by site.

<p>Excludes lost to follow-up and cases that did not have an outcome. Results estimated via random effects modeling to account for clustering by cohort. The 95% confidence limits were estimated using exact (Clopper-Pearson) method. *Unpublished data.</p

Clinical variables associated with treatment outcome in children with MDR-TB: <i>N</i> = 975.

<p>Clinical variables associated with treatment outcome in children with MDR-TB: <i>N</i> = 975.</p

Summary of treatment outcomes for children treated for MDR-TB.

<p>Summary of treatment outcomes for children treated for MDR-TB.</p

Comparing treatment success rates among children with MDR-TB infected with HIV, by timing of initiation of ART and by HIV status^a.

<p>Comparing treatment success rates among children with MDR-TB infected with HIV, by timing of initiation of ART and by HIV status<a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1002591#t004fn001" target="_blank">^a</a>.</p

Tuberculosis case definitions and treatment outcome definitions.

<p>Tuberculosis case definitions and treatment outcome definitions.</p

Demographic and clinical characteristics among children with MDR-TB.

<p>Demographic and clinical characteristics among children with MDR-TB.</p

Summary of association of use of individual drugs with treatment success in children treated for confirmed MDR-TB (<i>n</i> = 641)^a^,^b^,^c^,^d.

<p>Summary of association of use of individual drugs with treatment success in children treated for confirmed MDR-TB (<i>n</i> = 641)<a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1002591#t006fn002" target="_blank">^a</a>^,<a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1002591#t006fn003" target="_blank">^b</a>^,<a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1002591#t006fn004" target="_blank">^c</a>^,<a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1002591#t006fn005" target="_blank">^d</a>.</p

Study selection.

<p>IPD, individual patient data; XDR-TB, extensively drug resistant tuberculosis.</p