КОМПЛЕКСНОЕ ПРИМЕНЕНИЕ МЕТОДОВ ИФА И ПЦР ДЛЯ ДИАГНОСТИКИ ЭПШТЕЙН-БАРР ВИРУСНОЙ ИНФЕКЦИИ

The article discusses the results of the examination of patients with FBUN TNIIKIP of Rospotrebnadzor for Epstein-Barr-virus infection. It was confirmed that a combination of ELISA and PCR methods provides more complete information for making a clinical diagnosis than when isolated using them.В статье рассматриваются результаты обследования пациентов ФБУН ТНИИКИП Роспотребнадзора на Эпштейн-Барр-вирусную инфекцию. Подтвердилось, что сочетание методов ИФА и ПЦР дает более полную информацию для постановки клинического диагноза, чем при изолированном их применении

Glutamate Concentration in the Serum of Patients with Schizophrenia

Glutamate is the major neurotransmitter with multiple functions in the central nervous system. Glutamate-mediated excitotoxicity is involved in the pathophysiological processes in schizophrenia. The purpose of this study was to determine the concentration of glutamate in the serum of patients with paranoid schizophrenia compared with healthy individuals, and depending on the duration of the schizophrenic process and leading clinical symptoms. We investigated the level of glutamate in the serum of 158 patients with paranoid schizophrenia and 94 healthy persons. Higher concentrations of glutamate in schizophrenic patients compared with healthy persons have been found. The maximum concentrations of glutamate were detected in patients with disease duration of more than ten years. Glutamate level in the serum does not depend on the prevailing negative or positive clinical symptoms. The increased concentration of glutamate can hypothetically contribute to dopaminergic and glutamatergic imbalance, leading to the development of psychotic symptoms and cognitive dysfunction

Preliminary studies of surface water quality in Damodar River basin (West Bengal, India)

The purpose of the research was to study the main parameters of the chemical composition of surface water and its quality in the Damodar River basin near the Durgapur city where the surface water is used for water supply of the local community. During fieldwork water of the Damodar River, its tributaries (Tamla River and small streams - receivers of industrial wastewater and drainage water) and the Maithon Reservoir was sampled from the layer 0.1-0.5 m. Preliminary studies have shown that the main pollutants in the study area are organic compounds, ammonium, phosphate and fluoride ions. Deterioration of water quality in some sampling points is connected with a low content of dissolved oxygen and high concentrations of nitrite, chloride and sulfate ions

Preliminary studies of surface water quality in Damodar River basin (West Bengal, India)

The purpose of the research was to study the main parameters of the chemical composition of surface water and its quality in the Damodar River basin near the Durgapur city where the surface water is used for water supply of the local community. During fieldwork water of the Damodar River, its tributaries (Tamla River and small streams - receivers of industrial wastewater and drainage water) and the Maithon Reservoir was sampled from the layer 0.1-0.5 m. Preliminary studies have shown that the main pollutants in the study area are organic compounds, ammonium, phosphate and fluoride ions. Deterioration of water quality in some sampling points is connected with a low content of dissolved oxygen and high concentrations of nitrite, chloride and sulfate ions

Evaluation of mutagenic activity of external factors

Petrochemical enterprises dominate the system of the economic potential of our country. These enterprises, according to Russian legislation, are classified as carcinogenic. The technological process of this industry has excellent potential for improvement, which is predominantly expressed in the areas of technological, sanitary, and technical labor protection. However, according to the technical regulations, it is challenging to achieve complete industrial safety, which forms the list of problems of carcinogenic industrial facilities. Hence, the main objective of the present study is to evaluate the mutagenic activity of external factors. To accomplish that aim, experimental research is conducted. The results of this research can serve as a starting point in developing preventive measures to reduce the level of mutagenic hazard at carcinogenic enterprises.Las empresas petroquímicas dominan el sistema del potencial económico de nuestro país. Estas empresas, según la legislación rusa, están clasificadas como cancerígenas. El proceso tecnológico de esta industria tiene un excelente potencial de mejora, que se expresa predominantemente en las áreas de protección tecnológica, sanitaria y técnica laboral. Sin embargo, de acuerdo con los reglamentos técnicos, es un desafío lograr una seguridad industrial completa, que forma parte de la lista de problemas de las instalaciones industriales cancerígenas. Por lo tanto, el objetivo principal del presente estudio es evaluar la actividad mutagénica de factores externos. Para lograr ese objetivo, se lleva a cabo una investigación experimental. Los resultados de esta investigación pueden servir como punto de partida en el desarrollo de medidas preventivas para reducir el nivel de riesgo mutagénico en empresas cancerígenas