Slide in Centric on a Random Sample of Students of the School of Medicine in Split

Introduction: A slide in centric is defined as a slide from centric relation to maximum intercuspation. Understanding contact between natural teeth is important for longevity of the stomatognathic system, diagnosis and therapy planning. The aim of this study was to determine the difference in the length of slide in centric in population according to dental status, sex and previous orthodontic therapy. Materials and methods: The study was conducted on a sample of 33 students at the University of Split, School of Medicine (dental study). Results: Slide values do not follow normal or Gaussian distribution according to the Kolmogorov–Smirnov test (p<0.05). For that reason, they were represented by the median as a measure of central tendency. The arithmetic mean of a slide in centric is 0.95 mm ± 0.47 mm. A slide in centric was not present in only 10% of the subjects. A slide between 0.5 mm and 1.5 mm to maximum intercuspation was present in 90% of the examinees. There was no statistically significant difference in the length of slide between the subjects who had all teeth and those who had missing teeth 1-4 (z= 0.507; p= 0.612). There was no significant difference in the length of slide between women and men (z= 0, p=1). There was no significant difference in the length of slide between the patients who underwent orthodontic therapy and those who did not (z=0.253; p=0.800). Conclusion: There is some controversy about slide in centric and its etiological role in the development of temporomandibular disorders. Slide in centric is very significant because it indicates occlusal instability and can eventually lead to temporomandibular dysfunction, which do not have to be of the same aetiology

Rad ne sadrži naslov na drugom jeziku.

Disfunkcija štitnjače predstavlja vodeći endokrini poremećaj u svijetu. Proveli smo presječno istraživanje na 4402 osobe iz tri hrvatske kohorte. Cilj ovog istraživanja bio je analizirati prevalenciju dijagnosticirane i nedijagnosticirane hipotireoze, hipertireoze (subkliničke i kliničke) te pozitivnih protutijela na štitnjaču u hrvatskoj populaciji. Rezultati istraživanja pokazali su da je 17,6% ispitanika bilo u eutireozi s pozitivnim protutijelima. Prevalencija kliničke i subkliničke hipotireoze bila je 3% odnosno 7,4%, dok je prevalencija kliničke i subkliničke hipertireoze bila 0,2% odnosno 1,1%. Među njima, 92,6% ispitanika sa supkliničkom hipotireozom, 93,9% kliničkom hipotireozom, 83% supkliničkom hipertireozom i 71,4% ispitanika s kliničkom hipertireozom nije bilo dijagnosticirano. Konačno, prevalencija nedijagnosticirane subkliničke i kliničke hipotireoze u našoj populaciji bila je 6,9% odnosno 2,8%, dok je prevalencija nedijagnosticirane subkliničke i kliničke hipertireoze bila 0,9% odnosno 0,1%. Žene su pokazale veću prevalenciju poremećaja štitnjače; 1,57 puta veći izgledi za eutireozu s pozitivnim protutijelima, 2,1 puta veći izgledi za subkliničku hipertireozu, 2,37 puta veći izgledi za kliničku hipotireozu i 1,58 puta veći izgledi za subkliničku hipotireozu od muškaraca. Ovi rezultati ukazuju na iznimno visok udio nedijagnosticiranih slučajeva, te stoga ukazuju na važnost ulaganja u preventivne programe.Thyroid dysfunction appears to be the leading endocrine disorder. We conducted a cross-sectional study on 4402 individuals from three Croatian cohorts. The aim of this study was to analyse the prevalence of diagnosed and undiagnosed hypothyroidism, hyperthyroidism (subclinical and clinical) and positive thyroid antibodies in the Croatian population. The results of the study indicated that 17.6% of participants were euthyroid with positive antibodies. The prevalence of clinical and subclinical hypothyroidism was 3% and 7.4%, respectively, while the prevalence of clinical and subclinical hyperthyroidism was 0.2% and 1.1%, respectively. Among them, 92.6% subclinical hypothyroid, 93.9% clinical hypothyroid, 83% subclinical hyperthyroid and 71.4% clinical hyperthyroid participants were undiagnosed. Finally, the prevalence of undiagnosed subclinical and clinical hypothyroidism in our population was 6.9% and 2.8%, respectively, while the prevalence of undiagnosed subclinical and clinical hyperthyroidism was 0.9% and 0.1%, respectively. Women showed a higher prevalence of thyroid disorders; 1.57 times higher odds of euthyroidism with positive antibodies, 2.1 times higher odds of subclinical hyperthyroidism, 2.37 times higher odds of clinical hypothyroidism and 1.58 times higher odds of subclinical hypothyroidism than men. These results indicate an extremely high proportion of undiagnosed cases, and therefore require investments in a prevention programme

Rad ne sadrži naslov na drugom jeziku.

Disfunkcija štitnjače predstavlja vodeći endokrini poremećaj u svijetu. Proveli smo presječno istraživanje na 4402 osobe iz tri hrvatske kohorte. Cilj ovog istraživanja bio je analizirati prevalenciju dijagnosticirane i nedijagnosticirane hipotireoze, hipertireoze (subkliničke i kliničke) te pozitivnih protutijela na štitnjaču u hrvatskoj populaciji. Rezultati istraživanja pokazali su da je 17,6% ispitanika bilo u eutireozi s pozitivnim protutijelima. Prevalencija kliničke i subkliničke hipotireoze bila je 3% odnosno 7,4%, dok je prevalencija kliničke i subkliničke hipertireoze bila 0,2% odnosno 1,1%. Među njima, 92,6% ispitanika sa supkliničkom hipotireozom, 93,9% kliničkom hipotireozom, 83% supkliničkom hipertireozom i 71,4% ispitanika s kliničkom hipertireozom nije bilo dijagnosticirano. Konačno, prevalencija nedijagnosticirane subkliničke i kliničke hipotireoze u našoj populaciji bila je 6,9% odnosno 2,8%, dok je prevalencija nedijagnosticirane subkliničke i kliničke hipertireoze bila 0,9% odnosno 0,1%. Žene su pokazale veću prevalenciju poremećaja štitnjače; 1,57 puta veći izgledi za eutireozu s pozitivnim protutijelima, 2,1 puta veći izgledi za subkliničku hipertireozu, 2,37 puta veći izgledi za kliničku hipotireozu i 1,58 puta veći izgledi za subkliničku hipotireozu od muškaraca. Ovi rezultati ukazuju na iznimno visok udio nedijagnosticiranih slučajeva, te stoga ukazuju na važnost ulaganja u preventivne programe.Thyroid dysfunction appears to be the leading endocrine disorder. We conducted a cross-sectional study on 4402 individuals from three Croatian cohorts. The aim of this study was to analyse the prevalence of diagnosed and undiagnosed hypothyroidism, hyperthyroidism (subclinical and clinical) and positive thyroid antibodies in the Croatian population. The results of the study indicated that 17.6% of participants were euthyroid with positive antibodies. The prevalence of clinical and subclinical hypothyroidism was 3% and 7.4%, respectively, while the prevalence of clinical and subclinical hyperthyroidism was 0.2% and 1.1%, respectively. Among them, 92.6% subclinical hypothyroid, 93.9% clinical hypothyroid, 83% subclinical hyperthyroid and 71.4% clinical hyperthyroid participants were undiagnosed. Finally, the prevalence of undiagnosed subclinical and clinical hypothyroidism in our population was 6.9% and 2.8%, respectively, while the prevalence of undiagnosed subclinical and clinical hyperthyroidism was 0.9% and 0.1%, respectively. Women showed a higher prevalence of thyroid disorders; 1.57 times higher odds of euthyroidism with positive antibodies, 2.1 times higher odds of subclinical hyperthyroidism, 2.37 times higher odds of clinical hypothyroidism and 1.58 times higher odds of subclinical hypothyroidism than men. These results indicate an extremely high proportion of undiagnosed cases, and therefore require investments in a prevention programme

Rad ne sadrži naslov na drugom jeziku.

Disfunkcija štitnjače predstavlja vodeći endokrini poremećaj u svijetu. Proveli smo presječno istraživanje na 4402 osobe iz tri hrvatske kohorte. Cilj ovog istraživanja bio je analizirati prevalenciju dijagnosticirane i nedijagnosticirane hipotireoze, hipertireoze (subkliničke i kliničke) te pozitivnih protutijela na štitnjaču u hrvatskoj populaciji. Rezultati istraživanja pokazali su da je 17,6% ispitanika bilo u eutireozi s pozitivnim protutijelima. Prevalencija kliničke i subkliničke hipotireoze bila je 3% odnosno 7,4%, dok je prevalencija kliničke i subkliničke hipertireoze bila 0,2% odnosno 1,1%. Među njima, 92,6% ispitanika sa supkliničkom hipotireozom, 93,9% kliničkom hipotireozom, 83% supkliničkom hipertireozom i 71,4% ispitanika s kliničkom hipertireozom nije bilo dijagnosticirano. Konačno, prevalencija nedijagnosticirane subkliničke i kliničke hipotireoze u našoj populaciji bila je 6,9% odnosno 2,8%, dok je prevalencija nedijagnosticirane subkliničke i kliničke hipertireoze bila 0,9% odnosno 0,1%. Žene su pokazale veću prevalenciju poremećaja štitnjače; 1,57 puta veći izgledi za eutireozu s pozitivnim protutijelima, 2,1 puta veći izgledi za subkliničku hipertireozu, 2,37 puta veći izgledi za kliničku hipotireozu i 1,58 puta veći izgledi za subkliničku hipotireozu od muškaraca. Ovi rezultati ukazuju na iznimno visok udio nedijagnosticiranih slučajeva, te stoga ukazuju na važnost ulaganja u preventivne programe.Thyroid dysfunction appears to be the leading endocrine disorder. We conducted a cross-sectional study on 4402 individuals from three Croatian cohorts. The aim of this study was to analyse the prevalence of diagnosed and undiagnosed hypothyroidism, hyperthyroidism (subclinical and clinical) and positive thyroid antibodies in the Croatian population. The results of the study indicated that 17.6% of participants were euthyroid with positive antibodies. The prevalence of clinical and subclinical hypothyroidism was 3% and 7.4%, respectively, while the prevalence of clinical and subclinical hyperthyroidism was 0.2% and 1.1%, respectively. Among them, 92.6% subclinical hypothyroid, 93.9% clinical hypothyroid, 83% subclinical hyperthyroid and 71.4% clinical hyperthyroid participants were undiagnosed. Finally, the prevalence of undiagnosed subclinical and clinical hypothyroidism in our population was 6.9% and 2.8%, respectively, while the prevalence of undiagnosed subclinical and clinical hyperthyroidism was 0.9% and 0.1%, respectively. Women showed a higher prevalence of thyroid disorders; 1.57 times higher odds of euthyroidism with positive antibodies, 2.1 times higher odds of subclinical hyperthyroidism, 2.37 times higher odds of clinical hypothyroidism and 1.58 times higher odds of subclinical hypothyroidism than men. These results indicate an extremely high proportion of undiagnosed cases, and therefore require investments in a prevention programme

Epidemiology of Hypothyroidism, Hyperthyroidism and Positive Thyroid Antibodies in the Croatian Population

Thyroid dysfunction appears to be the leading endocrine disorder. We conducted a cross-sectional study on 4402 individuals from three Croatian cohorts. The aim of this study was to analyse the prevalence of diagnosed and undiagnosed hypothyroidism, hyperthyroidism (subclinical and clinical) and positive thyroid antibodies in the Croatian population. The results of the study indicated that 17.6% of participants were euthyroid with positive antibodies. The prevalence of clinical and subclinical hypothyroidism was 3% and 7.4%, respectively, while the prevalence of clinical and subclinical hyperthyroidism was 0.2% and 1.1%, respectively. Among them, 92.6% subclinical hypothyroid, 93.9% clinical hypothyroid, 83% subclinical hyperthyroid and 71.4% clinical hyperthyroid participants were undiagnosed. Finally, the prevalence of undiagnosed subclinical and clinical hypothyroidism in our population was 6.9% and 2.8%, respectively, while the prevalence of undiagnosed subclinical and clinical hyperthyroidism was 0.9% and 0.1%, respectively. Women showed a higher prevalence of thyroid disorders; 1.57 times higher odds of euthyroidism with positive antibodies, 2.1 times higher odds of subclinical hyperthyroidism, 2.37 times higher odds of clinical hypothyroidism and 1.58 times higher odds of subclinical hypothyroidism than men. These results indicate an extremely high proportion of undiagnosed cases, and therefore require investments in a prevention programme