The role of the neuromodulator adenosine in alcohols actions.

The interaction between the neuromodulator adenosine and adenosine receptors on the surface of neurons modifies the neurons responses to neurotransmitters. The activated adenosine receptors alter the levels of small signaling molecules (i.e., second messengers) in the cells. Depending on the receptors and cells involved, these changes can make it easier or more difficult for neurotransmitters to excite the cell. Adenosines activity is regulated by proteins called nucleoside transporters, which carry adenosine into and out of the cell. Alcohol interferes with the function of the adenosine system. For example, both acute and chronic alcohol exposure affect the function of the adenosine-carrying nucleoside transporters, thereby indirectly altering the second-messenger levels in the cells. Through this mechanism, adenosine may mediate some of alcohols effects, such as intoxication, motor incoordination, and sedation

Land Preservation in British Columbia: An Empirical Analysis of the Factors Underlying Public Support and Willingness to Pay

This study extends previous empirical research on land preservation by considering an actual land preservation scheme, the agricultural land reserve in British Columbia, Canada. The reserve was established in 1973 to ensure that development did not occur on the province’s most productive agricultural land. ‘To ensure that local food production is maintained,’ ‘the economic importance of British Columbia’s agricultural sector,’ and ‘to protect the environment’ are the most important factors that underlie support for the reserve. Aggregate, provincewide willingness to pay to maintain the land reserve is substantial, with our most conservative estimate being Can$91.18 million per year.agriculture, contingent, land, preservation, valuation, Agribusiness, Agricultural Finance, International Development, Resource /Energy Economics and Policy, Q15, Q24, Q28, Q51,

Education, 'Skills', and Technological Change: the Politics of the New Economy

This paper examines the prevalent view that technological change is having widespread effects on the pattern and natwe of employment in Aotearoa, and that these have significant implications for etlucation. We analyse papers by Callister (1990) on the labour market and MacPherson {1990) on education; two documents which have been influential in shaping policy directions. We then criticize the central points made in these, and other, documents, and consider the implications for education. Finally, we point out that arguments for a new relationship between education and the labour market are political, incorporating a fundamental debate about the narure of our society both now and in the future

On category O for cyclotomic rational Cherednik algebras

We study equivalences for category O_p of the rational Cherednik algebras H_p of type G_l(n) = \mu_l^n\rtimes S_n: a highest weight equivalence between O_p and O_{\sigma(p)} for \sigma\in S_l and an action of S_l on a non-empty Zariski open set of parameters p; a derived equivalence between O_p and O_{p'} whenever p and p' have integral difference; a highest weight equivalence between O_p and a parabolic category O for the general linear group, under a non-rationality assumption on the parameter p. As a consequence, we confirm special cases of conjectures of Etingof and of Rouquier.Comment: 61 pages; v2 64 pages, new material added; to appear J. Eur. Math. So

3.3 Gigahertz Clocked Quantum Key Distribution System

A fibre-based quantum key distribution system operating up to a clock frequency of 3.3GHz is presented. The system demonstrates significantly increased key exchange rate potential and operates at a wavelength of 850nm.Comment: Presented at ECOC 05, Glasgow, UK, (September 2005