1,101 research outputs found
Histamine N-methyltransferase Modulates Human Bronchial Smooth Muscle Contraction
To elucidate the modulatory role of histamine-degrading enzymes in
airway constrictor responses, human bronchial strips were studied
under isometric conditions in vitro. Pretreatment of tissues with
the histamine N-methyltransferase (HMT) inhibitor SKF 91488
specifically potentiated the contractile responses to histamine,
causing a leftward displacement of the concentration response curves,
whereas the diamine oxidase inhibitor aminoguanidine had no effect.
This potentiation was attenuated by mechanical removal of the
epithelium. The HMT activity was detected in the human bronchi,
which was less in the epithelium-denuded tissues than the
epithelium-intact tissues. These results suggest that HMT localized
to the airway epithelium may play a protective role against
histamine-mediated bronchoconstriction in humans
Superconductivity and Rattling under High Pressure in the beta-Pyrochlore Oxide RbOs2O6
Rattling-induced superconductivity in the beta-pyrochlore oxide RbOs2O6 is
investigated under high pressures up to 6 GPa. Resistivity measurements in a
high-quality single crystal show that the superconducting transition
temperature Tc increases gradually from 6.3 K at ambient pressure to 8.8 K at
3.5 GPa, surprisingly remains almost constant at 8.8 \pm 0.1 K in a wide
pressure range between 3.5 (Po) and 4.8 GPa, and suddenly drops to 6.3 K at Ps
= 4.9 GPa, followed by a gradual decrease with further pressure increase. Two
anomalies in the temperature dependence of the normal-state resistivity are
observed at Po Ps, revealing the presence of two high-pressure
phases corresponding to the changes in Tc. The rattling of the Rb ion inside a
cage made of Os and O atoms may be slightly and seriously modified in these
high-pressure phases that probably have cages of reduced symmetry,
respectively, so that electron-rattler interactions that govern the
superconducting and transport properties of beta-RbOs2O6 are significantly
affected.Comment: arXiv admin note: text overlap with arXiv:1009.035
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Simulation of premixed combustion with varying equivalence ratio in gas turbine combustor
RANS simulation of a gas turbine combustor with complex geometry is performed. The turbulence is modelled using a two-equation approach. The scalar mixing and combustion is modelled using a flamelet based approach for partially premixed combustion. In this approach transport equations to described scalar mixing and reacting fields and their statistical interactions are solved along with standard conservation equations. The boundary conditions are specified using measured values. The computed spatial variations of averaged temperature and dry mole fractions of various scalars, including CO and NOx, compared quite well with measured values. The results of this combustion model are compared to the eddy-dissipation-concept (EDC) model commonly used for gas turbine combustion calculation and this comparison showed that the results of partially premixed combustion model is improved considerably.This is the author accepted manuscript. The final version is available from the American Institute of Aeronautics and Astronautics via http://dx.doi.org/10.2514/1.B3551
Kerr/CFT correspondence and five-dimensional BMPV black holes
We apply a recently proposed Kerr/CFT correspondence to extremal
supersymmetric five-dimensional charged spinning black holes, constructed by
Breckenridge, Myers, Peet and Vafa. By computing the central charge of the dual
CFT and Frolov-Thorne temperature, Cardy's formula succeeds in reproducing
Bekenstein-Hawking area law.Comment: 10 pages, typos corrected, references added, explanation improved and
a missing factor 2 found; v3: a reference added, minor change
Sensitivity of the superconducting state and magnetic susceptibility to key aspects of electronic structure in ferropnictides
Experiments on the iron-pnictide superconductors appear to show some
materials where the ground state is fully gapped, and others where low-energy
excitations dominate, possibly indicative of gap nodes. Within the framework of
a 5-orbital spin fluctuation theory for these systems, we discuss how changes
in the doping, the electronic structure or interaction parameters can tune the
system from a fully gapped to nodal sign-changing gap with s-wave ()
symmetry (). In particular we focus on the role of the hole pocket at
the point of the unfolded Brillouin zone identified as crucial to
the pairing by Kuroki {\it et al.}, and show that its presence leads to
additional nesting of hole and electron pockets which stabilizes the isotropic
state. The pocket's contribution to the pairing can be tuned by doping,
surface effects, and by changes in interaction parameters, which we examine.
Analytic expressions for orbital pairing vertices calculated within the RPA
fluctuation exchange approximation allow us to draw connections between aspects
of electronic structure, interaction parameters, and the form of the
superconducting gap
Central Charges in Extreme Black Hole/CFT Correspondence
The Kerr/CFT correspondence has been recently broadened to the general
extremal black holes under the assumption that the central charges from the
non-gravitational fields vanish. To confirm this proposal, we derive the
expression of the conserved charges in the Einstein-Maxwell-scalar theory with
topological terms in four and five dimensions and check that the above
assumption was correct. Combining the computed central charge with the expected
form of the temperature, the Bekenstein-Hawking entropy of the general extremal
black holes in four and five dimensions can be reproduced by using the Cardy
formula.Comment: 20 pages, v2:references added, published in JHE
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