Toward a sustainable cybersecurity ecosystem

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Cybersecurity issues constitute a key concern of today’s technology-based economies. Cybersecurity has become a core need for providing a sustainable and safe society to online users in cyberspace. Considering the rapid increase of technological implementations, it has turned into a global necessity in the attempt to adapt security countermeasures, whether direct or indirect, and prevent systems from cyberthreats. Identifying, characterizing, and classifying such threats and their sources is required for a sustainable cyber-ecosystem. This paper focuses on the cybersecurity of smart grids and the emerging trends such as using blockchain in the Internet of Things (IoT). The cybersecurity of emerging technologies such as smart cities is also discussed. In addition, associated solutions based on artificial intelligence and machine learning frameworks to prevent cyber-risks are also discussed. Our review will serve as a reference for policy-makers from the industry, government, and the cybersecurity research community

Diabetics and Oral Health: A Case-Control Study

Background: Diabetes is a predominant health problem today and characterized by abnormally high blood sugar. According to World Health Organization (WHO) this clinical condition is increasing worldwide due to urbanization and physical inactivity uncontrolled diabetes develop ulceration, infection, tooth decay and decrease oral health status. Objectives: For the assessment of oral health condition and according to treatment required among the diabetic and non-diabetic patients is dental department of Cox’s Bazar Medical College Hospital, Cox’s Bazar. Method: This was a case-control type of study carried among 150 diabetics and 150 non-diabetics for 8 months period. Date was collected by direct interview of both diabetics and non-diabetics and clinical examination of oral cavity & also lab test. Results: Prevalence of Dental caries was higher in diabetics (58.6%) than non-diabetics (21.6%) and also prevalence of periodontal disease more in diabetics (93.2%) than non-diabetics (82.6%). Conclusion: Oral health is mirror image of general health. Dental caries and periodontal disease are more in diabetics than non-diabetics complex treatment required more in diabetics than non-diabetics. So, regular dental care is necessary for diabetic patients

Acceptability and short-term complications of PPIUCD

Background: Intrauterine contraceptive device (IUCD) is an effective form of long-acting reversible contraceptive (LARC). Postpartum IUCD insertion is labelled when IUCD is inserted within 10 minutes to 48 hours of expulsion of placenta. assess the acceptability and short-term complications of postpartum intrauterine contraception device insertion in tertiary care hospital of Bangladesh. The aim of the study was to assess the evaluation of factors associated with acceptability of post-partum intrauterine contraceptive device (PPIUCD). Methods: This was a prospective observational study was conducted at department of obstetrics and gynecology, Dhaka Medical College Hospital (DMCH). Results: Out of 360 eligible counselled postpartum patients, 48 (13.3%) women underwent PPIUCD insertion. Acceptance of PPIUCD was higher in the age group of 25-30 years (43.75%), having former health counselling about PPIUCD (70.8%), multipara (68.75%). The commonest complications were missing thread (8.3%) followed by lower abdominal pain (6.25%), irregular per vaginal bleeding (4.2%). Conclusions: PPIUCD is not very acceptable in our set up but it is a safe, highly effective method of contraception with very few side effects and no major complications and contraindications. The acceptability of PPIUCD can be increased with antenatal counselling and institutional delivery

Mortality causes in goldsmiths of Bangladesh: Findings from verbal autopsy

Background: Information on the mortality causes of goldsmiths in Bangladesh is limited. This study aimed to find out the mortality causes in a selected group of goldsmiths. Methods: A World Health Organization recommended questionnaire was adapted to conduct verbal autopsy of 20 deceased goldsmiths. Death-related information was gathered from the family members present during deceased’s illness preceding death. The mortality causes were determined by the interview outcomes and medical records-review. Results: The mean age of the goldsmiths at death was 59.2± 9.3 years. Among then, 70.0% were smokers and 50.0% were alcohol consumers. Cardiovascular diseases (CVD) were the most common immediate and underlying cause of death (60.0% and 45.0%, respectively). Conclusion: The life expectancy of goldsmiths was much lower than the average life expectancy of Bangladeshi population, where CVD was the primary cause of death. Smoking and alcohol consumption were prevalent among them. Awareness about healthy lifestyles should be prioritized for highly CVD prevention among the goldsmiths.  Bangabandhu Sheikh Mujib Medical University Journal 2023;16(2): 87-9

Factors Associated with Klebsiella

Although Klebsiella bacteremia in children is perceived to be associated with fatal consequences, data are scarce on those children presenting with diarrhea. We evaluated the factors associated with Klebsiella bacteremia in such children. In this retrospective chart analysis, data of all diarrheal children was retrieved from electronic medical record system (named as SHEBA) of Dhaka Hospital of International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), from January 1, 2010, to December 31, 2012, who had their blood culture done. This was a study having a case-control design where comparison of clinical and laboratory characteristics was done among children with Klebsiella bacteremia (cases = 30) and those without any bacteraemia (controls = 90). Controls were selected randomly. The cases more often had fatal outcome (p<0.001). In logistic regression analysis, after adjusting for potential confounders such as young age, severe dehydration, severe wasting, abnormal mentation, hypotension, and fast breathing, the cases were independently associated with hospital-acquired infection and positive stool growth (for all, p<0.05). The study highlights the importance of obtaining blood cultures in hospitalized children under five years old with diarrheal illness in the presence of either hospital-acquired infection or positive stool culture to have better outcome

Types and distribution of cancer patients attending in a tertiary care hospital of Bangladesh

Bangladesh, similar to other countries is experiencing an increased burden of cancer. Absence of a national cancer registry has created a gap in the information regarding the presentation of cancer statistics of the country. The objective of this study was to assess the types and distribution of the cancer patients attending a tertiary academic medical center hospital in Bangladesh. A cross-sectional study was conducted among all the confirmed cancer patients attending the in-patient and out-patient, and daycare facilities in Bangabandhu Sheikh Mujib Medical University in October, 2019. A validated questionnaire, recommended by International Agency for the Cancer Registry was used to collect data. Written informed consent was obtained from every respondent. This study had received its ethical clearance from Institutional Review Board of BSMMU. Among the 1656 respondents, 78.8% were adult and 25.2% were from paediatric age groups. Leading cancer for adult males were lung cancer (9.6%), leukaemia (9.4%) and lymphoma (9.0%); and breast cancer (28.1%), thyroid cancer (16.1%), and cervical cancer (12.2%) for females. Leukaemia was the most frequent cancer in the paediatric group for both males (71.5%) and females (66.5%). Establishing a hospital-based cancer registry with high quality data in an academic medical center setting is feasible and can set the stage for establishing nationwide hospital-based as well as establishing a popula- tion-based cancer registry in Bangladesh, which is necessary to identify and tackle the rising burden of cancer in this country. BSMMU J 2022; 15(1): 43-4

Vaccination following the expanded programme on immunization schedule could help to reduce deaths in children under five hospitalized for pneumonia and severe pneumonia in a developing country

BackgroundWorldwide, pneumonia is the leading cause of mortality in children under the age of five. An expanded program on immunization (EPI) is one kind of evidence-based tool for controlling and even eradicating infectious diseases.ObjectivesThis study aimed to explore the impact of EPI vaccination, including BCG, DPT-Hib-Hep B, OPV, IPV, and PCV-10, among children from the age of 4 to 59 months hospitalized for pneumonia and severe pneumonia. Additionally, we evaluated the role of 10 valent pneumococcal conjugate vaccines alone on clinical outcomes in such children.MethodsIn this retrospective chart review, children from the age of 4 to 59 months with WHO-defined pneumonia and severe pneumonia admitted to the Dhaka Hospital of the International Centre for Diarrheal Disease Research, Bangladesh (icddr,b) between August 2013 and December 2017 who had the information on immunization as per EPI schedule by 4 months of age were included in the analysis. A comparison was made between the children who were fully immunized (immunization with BCG, DPT-Hib-Hep B, OPV, and IPV from 2013 to 2015 and PCV-10 from 2015 to 2017) and who were not immunized (consisting of partial immunization and no immunization) during the study period.ResultsA total of 4,625 children had pneumonia and severe pneumonia during the study period. Among them, 2,605 (56.3%) had received the information on immunization; 2,195 (84.3%) were fully immunized by 4 months of age according to the EPI schedule and 410 were not immunized. In the log-linear binomial regression analysis, immunization of children from 4 to 59 months of age was found to be associated with a lower risk of diarrhea (p = 0.033), severe pneumonia (p = 0.001), anemia (p = 0.026), and deaths (p = 0.035). Importantly, the risk of developing severe pneumonia (1054/1,570 [67%] vs. 202/257 [79%], p &lt; 0.001) and case-fatality rate (57/1,570 [3.6%] vs. 19/257 [7.4%], p = 0.005) was still significantly lower among those who were immunized with PCV-10 than those who were not.ConclusionChildren immunized as per the EPI schedule were at a lower risk of diarrhea, severe pneumonia, anemia, and death, compared to unvaccinated children. In addition, PCV-10 was found to be protective against severe pneumonia and deaths in vaccinated children. The overall results underscored the importance of the continuation of immunization, scrupulously adhering to the EPI schedule to reduce the risk of morbidities and mortalities in children, especially in resource-limited settings

Impacts of COVID-19 Pandemic Lockdown on Road Safety in Bangladesh

The purpose of this research is to demonstrate the trends of crashes, injuries, and fatalities under the effect of the lockdown and observe the deviation of these trends from the anticipated values that would have been seen without the impact of the lockdown. To that end, data on road collisions, injuries, and fatalities in Bangladesh were compiled over four years (from January 2016 to May 2020) using the dataset from the Accident Research Institute (ARI). The pre-pandemic and lockdown period during the pandemic were included in the selected study period. To compare the observed values of the number of crashes, injuries, and fatalities to the forecasted values, which were meant to show assumed conditions without the emergence of the COVID-19 pandemic, different Autoregressive Integrated Moving Average (ARIMA) time series models were developed for each first-level administrative divisions (Dhaka, Chattogram, Khulna, Barishal, Rajshahi, Sylhet, Rangpur, and Mymensingh). Due to the mobility restrictions, the observed number of collisions, injuries, and deaths remained below the expected values, with a discernible high difference throughout the entire lockdown in Dhaka and Chattogram. In contrast, in the case of other divisions (Khulna, Barishal, Rajshahi, Sylhet, Rangpur, and Mymensingh), it remained under the expected trend for most of the lockdown period but not entirely. The mobility was not eliminated, resulting in a non-zero crash, injury, and fatality records across all divisions. In multiple instances, we observed that actual collision, injury, and fatality rates were higher than expected. Additionally, various divisions exhibited varying patterns of crashes, injuries, and fatalities during stay-at-home orders. Poor performance has been noted in terms of overall road safety during the pandemic era. Given the possibility of future waves of COVID-19 cases and other pandemics, the results of the current study can be used by local authorities and policymakers to improve road safety

Evaluation of serum interleukin‐1 receptor antagonist levels in major depressive disorder: A case‐control study

Abstract Background and Aims Major depressive disorder (MDD) is characterized by the occurrence of one or more depressive episodes lasting a minimum of 2 weeks and is marked by a persistently low mood and a lack of enjoyment in daily activities. The diagnosis of MDD is not possible by a well‐established laboratory test or biomarker. A wide range of potential biomarkers for depression have been proposed by many studies, but none of them has adequately described the correlation between the biomarkers and depression. The purpose of this study was to evaluate serum interleukin‐1 receptor antagonist (IL‐1RA) levels as an early depression risk factor. Methods The present case‐control study included 88 participants. Among them, 44 MDD patients enrolled from the psychiatry department of a public hospital in Dhaka, Bangladesh, and 44 age‐ and sex‐matched healthy controls (HCs) from various sites in Dhaka city. A qualified psychiatrist evaluated the cases and HCs based on the fifth edition of the diagnostic and statistical manual of mental disorders (DSM‐5). The Hamilton depression (Ham‐D) rating scale was employed to evaluate the intensity of depression. An enzyme‐linked immunosorbent assay kit (Boster Bio, USA) was used to determine serum IL‐1RA concentrations. Results We observed no marked alteration in the serum concentration of IL‐1RA in MDD patients in comparison to HCs (292.81 ± 24.81 and 288 ± 24.87 pg/mL; p > 0.05). Among MDD patients, we found no noteworthy association between the severity of depression and serum IL‐1RA levels. Conclusion The findings of the present study imply that IL‐1RA may not be identified as a promising biomarker for risk assessment of depression. However, its neuroprotective role may be taken into consideration for the understanding of pathophysiology of MDD

COVID-19 Testing: Perceived Barriers Among the Urban Slum Dwellers of Dhaka, Bangladesh

Background: Urban slum dwellers are unduly affected by COVID-19, and low testing rates among them are worsening their situation. This study aimed to explore the perceived barriers to COVID-19 testing in the slums, which is crucial to its surveillance, tracking, and allocating resources to combat the pandemic. Methods: A quantitative study with a cross-sectional design was conducted among 149 urban slum dwellers (≥11 years of age), who had previously experienced COVID-19 like symptoms. They were identified from an existing slum cohort at Bauniabadh, Dhaka. Information related to their testing status and perceived barriers was acquired by a telephone survey from October to November 2020. Results: The mean age of the respondents was 34.4±15.6 years, and 58.4% of them were female. Fever (79.2%) and cough (74.5%) were the most common symptoms mentioned. Only 6.7% of the respondents had undergone COVID-19 testing. Fast relief (within 1-3 days) from symptoms (87.6%) was the most prevailing barrier to testing, seen across all age and education groups. Negative advocacy regarding the testing from family and friends (46.7%), participants uncertainty about the guidelines, site, cost, and schedule of testing (15.3%), and a general belief that ‘COVID-19 is not a disease of slum people instead, it is an affliction of the rich folk’ (20.4%), were the other cited barriers. Conclusions: The COVID-19 testing rate remained very low among the urban slum dwellers. To remove the barriers to testing, tailored behavioral change communication and augmenting the resources for testing are necessary to curb the spread in the slums