Genes Dev

Almost half of our genome is occupied by transposable elements. Although most of them are inactive, one type of non-long terminal repeat (LTR) retrotransposon, long interspersed nuclear element 1 (LINE1), is capable of retrotransposition. Two studies in this issue, Pezic and colleagues (pp. 1410-1428) and Castro-Diaz and colleagues (pp. 1397-1409), provide novel insight into the regulation of LINE1s in human embryonic stem cells and mouse germ cells and shed new light on the conservation of complex mechanisms to ensure silencing of transposable elements in mammals

Comparative Research of Survey Results on the Usage Patterns of Traditional Garden between Japan and Austria

This study compares differences between Japan and Austria as regarding outdoor activities. We conducted a survey with respect to the utility patterns of Kairakuen Garden in Mito city, Ibaraki prefecture, which is one of the three major historical gardens in Japan noted for its beauty. This paper compares the results of our survey with a study of the recreational and spatial utility of the historical Schönbrunn Garden in Vienna, Austria, a baroque garden of the former Emperor of Austria. Therefore, both Japan and Austria universities examined the same questionnaire items such as where visitors are from, importance of motives of visiting, and wandering behavior at each gardens. Here, in this paper, common motives of visitors in both gardens are discovered. In addition, there were similarities between Kairakuen Garden and Schönbrunn Garden in that the citizens of Vienna frequently tends to avoid the routes that are used by many sightseers, and which can be observed also with the most local residents of Mito visiting the Kairakuen Garden

Overexpressing Transcriptional Regulator in Aspergillus oryzae Activates a Silent Biosynthetic Pathway to Produce a Novel Polyketide

10.1002/cbic.201200107ChemBioChem136855-861CBCH