3 research outputs found

    Nasopharyngeal carcinoma (NPC) with liver metastasis in pregnancy

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    Introduction: Cancer in pregnancies is the second most common cause of death after trauma in woman of reproductive age and confounds about 0.1 to 0.2% of pregnancies1,2) and rarely nasopharyngeal carcinoma being the aetiology. Objective: This report describes a pregnant woman in which an advanced-stage NPC was diagnosed and managed accordingly with a review of some related literature reviews. Case report: 29 year old Chinese lady was diagnosed with nasopharyngeal carcinoma (NPC) during her third trimester with very short history. She initially presented to us at 34 weeks of pregnancy with a painless right neck swelling and a chronic non-productive cough for one month duration. She was initially thought to have tuberculous lymphadenitis. A routine rigid endoscopic nasopharyngoscope examination revealed a right Fossa of Rosenmuller (FOR) mass. Biopsy of the nasal mass and fine needle aspiration cytology (FNAC) of the neck swelling further confirmed nasopharyngeal carcinoma- non keratinizing type. After discussion with her obstetrician and the patient, she underwent an elective induction of labor at 36 weeks of gestation, and delivered a healthy 2.77 kg baby boy. Computer tomography (CT) neck, thorax and abdomen were performed 2 weeks postpartum. The imaging showed fullness of the right FOR with metastases to right level 2 cervical lymph node along with metastatic deposits in 2 segments of the liver. She was then referred to oncology unit for further management. Conclusion: In conclusion, high index of suspicion is important in detection of NPC even in pregnant ladies with suspicious neck swelling. Method of detecting NPC early in pregnancy is essential in order to give optimize treatment, achieve potential for full recovery and also reduced the adverse risk and complications associated with NPC

    Primary localized amyloidosis in nasopharynx: a case report

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    Nasopharyngeal amyloidosis is an extremely rare benign tumour. It is divided into localized or systemic amyloidosis. It is more common in men. Clinical presentation includes nasal blockage, epistaxis and reduced hearing. Classical positive Congo red stain and appearance of apple green birefringence on polarized microscopy confirms the diagnosis of amyloidosis. We present a case of nasopharyngeal amyloidosis in a 44-year old lady who presented with acute hearing loss for 1 week with epistaxis mimicking nasopharyngeal carcinoma. Clinical examination showed a nasopharyngeal mass with biopsy proven AA amyloidosis. She is now cured of amyloidosis following endoscopic transnasal excision of tumour. We discuss on the similarity of presentation between nasopharyngeal carcinoma; the commonest malignant tumour in our region and the much rarer nasopharyngeal amyloidosis as well as highlighting the importance in early recognition of the latter in view of its known risk of systemic involvement

    Multiple Metastatic Deposits in the Head and Neck Region from a Renal Cell Carcinoma

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    Metastatic renal cell carcinoma (RCC) presenting with multiple deposits in the head and neck region is unusual. It is not uncommon for a RCC to metastasise to a distant site after years of a tumour-free period, but most of it would be expected to have a single site of deposit. We report a rare case of a patient who had a nephrectomy 10 years earlier for RCC and presented with tumours in the frontal sinus and posterior pharyngeal wall. Radiological imaging and histology confirmed metastatic RCC at both sites
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