39 research outputs found
A Study of the \eta \pi^{0} Spectrum and Search for a J^{PC} = 1^{-+} Exotic Meson
A partial wave analysis (PWA) of the of the system (where ) produced in the charge exchange reaction at an incident momentum of 18 GeV is presented as a function of
invariant mass, , and momentum transfer squared,
, from the incident to the outgoing system. , and waves were included in the PWA. The
and states are clearly observed in the overall
effective mass distribution as well as in the amplitudes associated with
wave and waves respectively after partial wave decomposition. The observed
distributions in moments (averages of spherical harmonics) were compared to the
results from the PWA and the two are consistent. The distribution in
for individual waves associated with natural and
unnatural parity exchange in the -channel are consistent with Regge
phenomenology. Of particular interest in this study is the wave since this
leads to an exotic for the system. A wave is
present in the data, however attempts to describe the mass dependence of the
amplitude and phase motion with respect to the wave as a Breit-Wigner
resonance are problematic. This has implications regarding the existence of a
reported exotic meson decaying into with a mass
near 1.4 GeV.Comment: 19 pages, 29 figures, to appear in Phys. Rev.
A partial wave analysis of the system produced in charge exchange collisions
A partial wave analysis of the of the system produced in the
charge exchange reaction: at an incident momentum of
is presented as a function of invariant mass,
, and momentum transfer squared, , from the incident
to the outgoing system.Comment: 24 pages total,8 pages text, 14 figures, 1 table. Submitted to Phys
Rev
Marine accidents in the Brazilian Amazon : the problems and challenges in the initiatives for their prevention focused on passenger ships
The Brazilian Amazon is part of one of the largest river systems in the world, in which the transport of cargo and passengers is commonplace. However, several accidents still occur to passenger ships, causing fatalities. Transportation occurs commonly in remote regions, where there are transport inequalities, and emergency assistance is hard to find. This can affect sustainability in communities with considerable levels of economic and social vulnerability. More information is needed about accidents involving inland transport in the Amazon, to identify the threats to ships and propose strategies for accident prevention. This paper addresses the main problems that long-distance passenger ships face in the Brazilian Amazon, presenting an integrated framework towards accident prevention. First, the present situation is characterized in terms of ship description, spatial distribution, and regulations that are applicable. Next, possible causes of passenger ship accidents are discussed, including topics of concern that should be considered in the Amazon waterways. Finally, measures to help minimize passenger ship accidents are proposed, and the social relevance is discussed. It was found that accidents in the Amazon are due to a combination of human and environmental factors. Stakeholders should strengthen the technical and legal training of ship operators. The use of new technologies for navigational aid and necessary maintenance of ships is suggested. Marine accident prevention initiatives should consider local conditions, such as environmental preservation, cultural respect, and difficulties related to navigation through the complex riverine system of the Amazon region
Phylogenomics and the rise of the angiosperms
Angiosperms are the cornerstone of most terrestrial ecosystems and human livelihoods1,2. A robust understanding of angiosperm evolution is required to explain their rise to ecological dominance. So far, the angiosperm tree of life has been determined primarily by means of analyses of the plastid genome3,4. Many studies have drawn on this foundational work, such as classification and first insights into angiosperm diversification since their Mesozoic origins5,6,7. However, the limited and biased sampling of both taxa and genomes undermines confidence in the tree and its implications. Here, we build the tree of life for almost 8,000 (about 60%) angiosperm genera using a standardized set of 353 nuclear genes8. This 15-fold increase in genus-level sampling relative to comparable nuclear studies9 provides a critical test of earlier results and brings notable change to key groups, especially in rosids, while substantiating many previously predicted relationships. Scaling this tree to time using 200 fossils, we discovered that early angiosperm evolution was characterized by high gene tree conflict and explosive diversification, giving rise to more than 80% of extant angiosperm orders. Steady diversification ensued through the remaining Mesozoic Era until rates resurged in the Cenozoic Era, concurrent with decreasing global temperatures and tightly linked with gene tree conflict. Taken together, our extensive sampling combined with advanced phylogenomic methods shows the deep history and full complexity in the evolution of a megadiverse clade
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
INTRODUCTION
Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic.
RATIONALE
We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs).
RESULTS
Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants.
CONCLUSION
Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century
PRESIDENTIAL ADDRESS: UNITY OUT OF DIVERSITY: THE RUMINATIONS OF A TRADITIONAL GEOGRAPHER
Combined training enhances skeletal muscle mitochondrial oxidative capacity independent of age
CONTEXT: Skeletal muscle from sedentary older adults exhibits reduced mitochondrial abundance and oxidative capacity. OBJECTIVE: The primary objective was to determine whether 8 weeks of combined training (CT) has a more robust effect than endurance training (ET) or resistance training (RT) on mitochondrial physiology in healthy young (18–30 years) and older (≥65 years) adults. INTERVENTION: Thirty-four young and 31 older adults were randomly assigned to 8 weeks of ET, RT, and control/CT. Control subjects completed 8 weeks of no exercise (control) followed by 8 weeks of CT. Body composition, skeletal muscle strength, and peak oxygen uptake were measured before and after the intervention. Vastus lateralis muscle biopsy samples were obtained before and 48 hours after the intervention. Mitochondrial physiology was evaluated by high-resolution respirometry and expression of mitochondrial proteins and transcription factors by quantitative PCR and immunoblotting. RESULTS: ET and CT significantly increased oxidative capacity and expression of mitochondrial proteins and transcription factors. All training modalities improved body composition, cardiorespiratory fitness, and skeletal muscle strength. CT induced the most robust improvements in mitochondria-related outcomes and physical characteristics despite lower training volumes for the ET and RT components. Importantly, most of the adaptations to training occurred independent of age. CONCLUSION: Collectively, these results demonstrate that both ET and CT increase muscle mitochondrial abundance and capacity although CT induced the most robust improvements in the outcomes measured. In conclusion, CT provides a robust exercise regimen to improve muscle mitochondrial outcomes and physical characteristics independent of age
