372 research outputs found

    Items to be Included in a Food Safety Handbook for Artisan Cheese Makers

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    Current written resources for artisan cheese makers include topics concerning cheese history, cheese recipes, budget planning, culture selection, processing parameters, and only limited discussion of food safety associated with cheese manufacturing. Most often food safety discussions center on HACCP, which typically are not included in artisan cheese operation planning. Recent changes in the regulatory landscape, including the Food Safety Modernization Act, make this information timely and needed. This research is designed to identify and collect a majority of topical ideas that should be included in a Food Safety Handbook for Artisan Cheese Makers. Where possible, expansion of the ideas has been included. It is felt that this information, once collected could be put in a handbook for artisan cheese makers that would provide a day-to-day reference manual for making safe, high quality Artisan cheese

    UNLV New Horizons Band

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    Program listing performers and works performed

    The determination of the elastic modulus of rubber mooring tethers and their use in coastal moorings

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    Compliance must be supplied to any surface mooring to allow the buoy to move with the waves and currents, and remain moored in position. This can be supplied with a traditional chain catenary or newer compliant elastic tether or stretch hose technologies. Some applications of each of these three techniques are shown, with the emphasis placed on the use of compliant elastic tethers. For modeling and designing these moorings, the elastic modulus of the tether material must be known. Therefore, a new and used piece of elastic material was terminated, tested for the stretch-strain relationship under set conditions, and the elastic modulus calculated. For these tests, the elastic tether was stretched out to a mean elongation between 100 and 250%, then cycled about that stretch by ±25 and ±50% to duplicate a moored application. The resultant elastic modulus is presented to aid in mooring design. At low elongations, the elastic modulus is constant at about 125 PSI, but as the mean elongation increases the modulus increases, and as the cycle tension increase the modulus also increases, reaching a maximum of 900 PSI at 275% stretch.Funding was provided by the Gulf of Maine Ocean Observing System (GoMOOS under ONR grant N0014-01-1-0999), NOAA-UNH CINEMAR (NOAA Grant Number NA16RP1718), and GLOBEC (NSF OCE93-13670 and OCE02-27679)

    Disease gravity and urgency of need as guidelines for liver allocation

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    One thousand one hundred and twenty-eight candidates for liver transplantation were stratified into five urgency-of-need categories by the United Network for Organ Sharing (UNOS) criteria. Most patients of low-risk UNOS 1 status remained alive after 1 yr without transplantation; the mortality while waiting was 3% after a median of 229.5 days. In contrast, only 3% of those entered at the highest risk UNOS 5 category survived without transplantation; 28% died while waiting, the deaths occurring at a median of 5.5 days. The UNOS categories in between showed the expected gradations, in which at each higher level fewer patients remained as candidates throughout the 1-yr duration of study while progressively more died at earlier and earlier times while waiting for an organ. In a separate study of posttransplantation survival during the same time period, the best postoperative results were in the lowest-risk UNOS 1 and 2 patients (88% combined), and the worst results were those in UNOS 5 (71%). However, a relative risk cross-analysis showed that a negative benefit of transplantation may have been the result in terms of 1-yr survival for the low-risk elective patients, but that a gain in life extension was achieved in the potentially lethal UNOS categories 3, 4 and 5 (greatest for UNOS 3). These findings and conclusions are discussed in terms of total care of patients with liver disease, and in the context of organ allocation policies of the United States and Europe

    Biomimetic surfaces via dextran immobilization : grafting density and surface properties

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    Biomimetic surfaces were prepared by chemisorption of oxidized dextran (Mw = 110 kDa) onto SiO2 substrates that were previously modified with aminopropyl-tri-ethoxy silane (APTES). The kinetics of dextran oxidation by sodium metaperiodate (NaIO4) were quantified by 1H NMR and pH measurements. The extent of oxidation was then used to control the morphology of the biomimetic surface. Oxidation times of 0.5, 1, 2, 4, and 24 hours resulted in \u3c20, ~30, ~40, ~50 and 100% oxidation, respectively. The surfaces were characterized by contact angle analysis and atomic force microscopy (AFM). Surfaces prepared with low oxidation times revealed a more densely packed brushy layer when imaged by AFM than those prepared at low oxidation times. Finally, the contact angle data revealed, quite unexpectedly, that the surface with the greatest entropic freedom (0.5 h) wetted the fastest and to the greatest extent (THETAAPTES \u3e THETA1h \u3e THETA2,4h \u3e THETA0.5h)

    Joint Modeling and Registration of Cell Populations in Cohorts of High-Dimensional Flow Cytometric Data

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    In systems biomedicine, an experimenter encounters different potential sources of variation in data such as individual samples, multiple experimental conditions, and multi-variable network-level responses. In multiparametric cytometry, which is often used for analyzing patient samples, such issues are critical. While computational methods can identify cell populations in individual samples, without the ability to automatically match them across samples, it is difficult to compare and characterize the populations in typical experiments, such as those responding to various stimulations or distinctive of particular patients or time-points, especially when there are many samples. Joint Clustering and Matching (JCM) is a multi-level framework for simultaneous modeling and registration of populations across a cohort. JCM models every population with a robust multivariate probability distribution. Simultaneously, JCM fits a random-effects model to construct an overall batch template -- used for registering populations across samples, and classifying new samples. By tackling systems-level variation, JCM supports practical biomedical applications involving large cohorts
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