Evolution of Left Ventricular End Systolic Volume over time of late non-responders.

<p>At six-month follow-up late non-responders showed a significant median decrease of left ventricular end systolic volume (LVESV) of 28%. However, at 14-month follow-up, LVESV almost returned to baseline values again.</p

Flow chart of responders and non-responders.

<p>Flow chart of responders and non-responders.</p

Baseline data of six-month responders, and stratified by late non-responders and stable responders.

<p>p-value between late non-responders and stable responders:</p><p>* = p < 0.05,</p><p>^# = p < 0.001</p><p>ACE: angiotensin-converting enzyme, BNP: B-type natriuretic peptide, IQR: Interquartile range, IVCD: Interventricular conduction delay, IVMD: Interventricular mechanical delay, LA: Left atrium, LBBB: Left bundle branch block, LVEDV: left ventricular end diastolic volume, LVEF: left ventricular ejection fraction, LVESV: left ventricular end systolic volume, NYHA: New York Heart Association, RA: Right atrium, RBBB: Right bundle branch block, RV: Right ventricle, SRS_sept: Systolic Rebound Stretch of the Septum</p><p>Baseline data of six-month responders, and stratified by late non-responders and stable responders.</p

MACE between 14–24 months after implantation in 6 and 14-month responders and non-responders.

<p>MACE: Major adverse cardiac events</p><p>MACE between 14–24 months after implantation in 6 and 14-month responders and non-responders.</p