14 research outputs found

    ZZ-boson polarization as a model-discrimination analyzer

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    Determining the spin of any new particle is critical in identifying the true theory among various extensions of the Standard Model (SM). The degree of ZZ-boson polarization in any two-body decay process A→BZA\to B Z is sensitive to the spin assignments of two new particles AA and BB. Considering all possible spin-0, 1/2 and 1 combinations in a renormalizable field theory, we demonstrate that ZZ-boson polarization can indeed play a role of a decisive and universal analyzer in distinguishing the different spin assignments.Comment: 10 pages, 3 figures, 1 tabl

    Periconceptional maternal dairy-rich dietary pattern is associated with prenatal cerebellar growth

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    <div><p>Background</p><p>Maternal nutrition during pregnancy has been related to intrauterine brain development and neurodevelopmental disabilities in adult life. We aim to investigate associations between periconceptional maternal dietary patterns and prenatal cerebellar growth from the first trimester onwards.</p><p>Materials and methods</p><p>126 women with singleton non-malformed pregnancies were enrolled before 8 weeks of gestation in the Rotterdam periconceptional cohort between 2013 and 2015. Periconceptional maternal dietary patterns were extracted from food frequency questionnaires and associated with blood biomarkers and micronutrient intakes. Serial two-dimensional and three-dimensional ultrasound scans were performed at 9, 11, 22, 26 and 32 weeks of gestation for transcerebellar diameter (TCD) measurement. Linear mixed models were estimated to investigate associations between periconceptional maternal dietary patterns and longitudinal TCD measurements as a function of gestational age.</p><p>Results</p><p>We performed a median of 4 scans per pregnancy, resulting in 570 total datasets. The success rate of TCD measurements was 87% (range 65–100%), depending on gestational age. The Mediterranean, Western, egg-rich and dairy-rich dietary patterns were extracted, explaining 37.2% of the overall variance of food intake in this population. The dairy-rich dietary pattern was positively associated with cerebellar growth trajectories (β = 0.02 (95% CI: 0.01; 0.03) √mm, p = 0.01). Maternal strong adherence to this dietary pattern increased TCD measurements by 0.8 standard deviation scores (SDs) compared to weak adherence, reflected in increased TCD estimates of 0.44 mm at 9 weeks (+6.8%), 0.88 mm at 22 weeks (+3.6%), and 1.17 mm at 32 weeks (+2.8%). No significant associations were detected for the Mediterranean, Western and egg-rich dietary patterns.</p><p>Conclusions</p><p>This study shows a positive association between periconceptional maternal adherence to a dairy-rich dietary pattern and human prenatal TCD measurements as a proxy of cerebellar growth. Next step is the investigation of the impact on neurodevelopmental outcomes in the offspring.</p></div

    Associations between the adherence to the periconceptional maternal dairy-rich dietary pattern and longitudinal transcerebellar diameter (TCD) measurements after transformation to the original scale (mm) in the study population using model 2.

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    <p>The adherence to the dietary pattern is expressed as -2 standard deviation (SD) (weak) or +2SD (strong) in component score. Full adjustment, including energy intake, conception mode, alcohol, smoke, parity, age, BMI, folic acid supplement/multivitamin use and ethnicity, was performed. GA: gestational age; CI: confidence interval.</p

    Longitudinal transcerebellar diameter (TCD, mm) measurements in the study population.

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    <p>Mean values at 9, 11, 22, 26 and 32 weeks of gestation are reported. Dots and lines represent TCD measurements and trajectories of a single included pregnancy. n: number; GA: gestational age.</p

    Associations between periconceptional red blood cell folate quartiles and cerebellar growth trajectories.

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    <p>Linear mixed models representing the effects of red blood cell folate quartiles on cerebellar growth trajectories as a function of CRL in millimetres and GA in days. The blue line represents the third quartile used as reference.</p
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