New 2,4,6-substituted 1,3-dioxanes: synthesis, stereochemistry and thermodynamic data determinations by cis-trans isomers equilibrium

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Results regarding the chemical control of European cherry fruit fly (Rhagoletis cerasi L.) in cherry orchards from Cluj area

In neglected orchards the attack of European cherry fruit fly can affect the production by up to compromising. For framing in the regulations asked by market, it is often required that in cherry plantations to intervene with several strategies of pest control, in which frequently appears chemotherapy. To apply a reduced number of treatments we must know the biological reserve of species and its life cycle. The experiment was conducted over two years, 2013- 2014, in an orchard located near Cluj-Napoca city, Romania.To study the biological cycle of this species, we followed the dynamics of climatic factors, especially the accumulation of active degrees that were needed in going through several stages of development. In order to apply the treatments, we observed flight dynamics of Rhagoletis cerasi using sticky panels (provided by Institute of Chemistry "Raluca Ripan'' Cluj-Napoca). The treatments applyed in combating of the fly consisted in two applications of products belonging to synthetic pyrethroids group. In 2013, the first adults were recorded on 25 May, when the amount of active degrees accumulated was 410, 2 ° C. Frequency of fruits attacked by cherries worm this year was 1%. In 2014, the adults emergence took place on May 21, which corresponded to value of 343,8° C degrees acumulated. Although the population level was still high the frequency of attacked fruits was again 1%, which was mainly due to the possibility of migration of adults at distances over 100 m. In control variant, an untreated orchard, frequency of attacked fruits in both years exceeded 30%

Well-Being, Depression, and Anxiety following Oncoplastic Breast Conserving Surgery versus Modified Radical Mastectomy Followed by Late Breast Reconstruction

Breast cancer requires complex clinical care. Well-being is an intricate concept, encompassing physical, functional, emotional, and social aspects. Background: This study aims to evaluate the relationship between the type of surgery our patients underwent and the timing of the reconstructive surgery with physical, emotional, social, and functional well-being. Furthermore, through our research we tried to identify potential mental health comorbidities in patients with breast cancer, clinical symptoms, and well-being in women with breast cancer, depending on the type of required surgery. Methods: The study included 69 women diagnosed with breast cancer, in stages I to III, divided in two groups: I—patients with oncoplastic breast-conserving surgery and contralateral correction surgery, for symmetry reasons; II—patients who underwent modified radical mastectomy and late breast reconstruction with contralateral symmetrisation. We evaluated socio-demographic aspects, alongside depression, anxiety, stress (DASS 21), and well-being (FACT-B). Data were statistically processed; statistical significance was set at p < 0.05. Results: Clinical elements of depression, anxiety, and stress were noted in both groups, without statistical significance (p > 0.05). Significant differences were found regarding psycho-emotional (p = 0.035) and functional well-being (p = 0.001), with higher scores for group I. The chi-square test indicated statistically significant differences (at p < 0.01) between the groups, regarding the frequency of scores on items B4 and B9 (FACT-B items, related to feminine aesthetics and desirability), with evidently higher scores in group I than in group II. Conclusions: The state of well-being, as well as the items related to femininity and sexuality had higher values in the group of women treated by oncoplastic conservative surgery compared to late reconstruction after modified radical mastectomy