Network reconstruction from infection cascades

International audienc

Brief communication: Towards a universal formula for the probability of tornadoes

A methodological approach is proposed to provide an analytical (exponential-like) expression for the probability of occurrence of tornadoes as a function of the convective available potential energy and the wind shear (or, alternatively, the storm relative helicity). The resulting expression allows the probability of tornado occurrence to be calculated using variables that are computed by weather prediction and climate models, thus compensating for the lack of resolution needed to resolve these phenomena in numerical simulations

Search for exoplanets in M31 with pixel-lensing and the PA-99-N2 event revisited

Several exoplanets have been detected towards the Galactic bulge with the microlensing technique. We show that exoplanets in M31 may also be detected with the pixel-lensing method, if telescopes making high cadence observations of an ongoing microlensing event are used. Using a Monte Carlo approach we find that the mean mass for detectable planetary systems is about $2 M_{\rm {J}}$. However, even small mass exoplanets ($M_{\rm P} < 20 M_{\oplus}$) can cause significant deviations, which are observable with large telescopes. We reanalysed the POINT-AGAPE microlensing event PA-99-N2. First, we test the robustness of the binary lens conclusion for this light curve. Second, we show that for such long duration and bright microlensing events, the efficiency for finding planetary-like deviations is strongly enhanced with respect to that evaluated for all planetary detectable events.Comment: 14 pages, 8 figures. Paper presented at the "II Italian-Pakistani Workshop on Relativistic Astrophysics, Pescara, July 8-10, 2009. To be published in a special issue of General Relativity and Gravitation (eds. F. De Paolis, G.F.R. Ellis, A. Qadir and R. Ruffini

Apoastron Shift Constraints on Dark Matter Distribution at the Galactic Center

The existence of dark matter (DM) at scales of few pc down to $\simeq 10^{-5}$ pc around the centers of galaxies and in particular in the Galactic Center region has been considered in the literature. Under the assumption that such a DM clump, principally constituted by non-baryonic matter (like WIMPs) does exist at the center of our galaxy, the study of the $\gamma$-ray emission from the Galactic Center region allows us to constrain both the mass and the size of this DM sphere. Further constraints on the DM distribution parameters may be derived by observations of bright infrared stars around the Galactic Center. Hall and Gondolo \cite{hallgondolo} used estimates of the enclosed mass obtained in various ways and tabulated by Ghez et al. \cite{Ghez_2003,Ghez_2005}. Moreover, if a DM cusp does exist around the Galactic Center it could modify the trajectories of stars moving around it in a sensible way depending on the DM mass distribution. Here, we discuss the constraints that can be obtained with the orbit analysis of stars (as S2 and S16) moving inside the DM concentration with present and next generations of large telescopes. In particular, consideration of the S2 star apoastron shift may allow improving limits on the DM mass and size.Comment: in press on Phys. Rev.

Estimations of length-weight relationships and consumption rates of odontocetes in the Mediterranean Sea from stranding data

Stranding data provide fundamental information on biometric traits of cetaceans useful to increase knowledge on ecological traits and their consumption patterns. In this study, the length weight (L-W) relationships through the power regression model (W = a ×Lb ) were calculated for three dolphin species (the striped dolphin, the common bottlenose dolphin and the Risso’s dolphin) in several Mediterranean subregions and at the scale of the entire basin. Length (L) and weight (W) data were collected from stranding records during the period from 1983 to 2021 acquired from several databases and the literature. Starting from L-W relationships, a bootstrap method was applied to estimate the mean body weights, the daily ingested biomass (IB) and annual food consumption (AFC) rates of different dolphin species. In particular, four different equations were used to estimate the IB rates. Prey consumption by dolphin species was calculated through AFC rates and the available diet information (expressed in weight fractions) of dolphin species for different Mediterranean subregions. Considering the L-W relationships in the Mediterranean Sea, b coefficient values were equal to 2.578, 2.975 and 2.988 for the striped, the common bottlenose and the Risso’s dolphin, respectively. At the Mediterranean scale, the AFC values estimated were 3913 kg (CI 2469–5306) for the Risso’s dolphin, 2571 kg (1372–3963) for the common bottlenose dolphin and 1118 kg (531–1570) for the striped dolphin. Prey consumption pattern showed a clear partitioning among the investigated species, where the common bottlenose dolphin exploits neritic demersal and pelagic fishes (e.g. eel fishes, sparids), the striped dolphin exploits mesopelagic fishes and myctophids, and the Risso’s dolphin was specialized on bathyal cephalopods of Histioteuthidae family. The results obtained in this study provide new information for the investigated species in several Mediterranean subregions providing a first consistent baseline to support the population dynamics modelling. At the same time, the wide uncertainty ranges of some parameters, as well as the lack of information for some species, stress the necessity of improving the data collection associated to stranding events, especially in the southern Mediterranean areas

Microlensing signature of a white dwarf population in the galactic halo

Microlensing and pixel-lensing surveys play a fundamental role in the searches for galactic dark matter and in the study of the galactic structure. Recent observations suggest the presence of a population of old white dwarfs with high proper motion, probably in the galactic halo, with local mass density in the range $1.3\times 10^{-4}-4.4\times 10^{-3} M_{\odot}$ pc$^{-3}$, in addition to the standard galactic stellar disk and dark halo components. Investigation of the signatures on microlensing results towards the LMC of these different lens populations, with particular emphasis to white dwarfs, is the main purpose of the present paper. This is done by evaluating optical depth and microlensing rate of the various lens populations and then calculating through a Montecarlo program, the probability that a lens which has caused a microlensing event of duration $t_{\rm E}$ belongs to a certain galactic population. Data obtained by the MACHO Collaboration allow us to set an upper bound of $1.6\times 10^{-3} M_{\odot}$ pc$^{-3}$ to the local mass density of white dwarfs distributed in spheroidal models, while for white dwarfs in disk models all values for the local mass density are in agreement with observational results.Comment: in press on International Journal of modern Physics

Top-down cascading effects driven by the odontocetes in the Gulf of Taranto (Northern Ionian Sea, Central Mediterranean Sea)

An investigation of the marine food web in the Gulf of Taranto (Northern Ionian Sea, Central Mediterranean Sea) was carried out to explore the top-down cascading effects driven by the Odontocetes. The food web was analysed by a mass-balance model using 51 functional groups and detailing the trophic impacts of the striped and common bottlenose dolphins, the Risso's dolphin and the sperm whale during the period 2010-2014. Odontocetes resulted top-predators with the highest TL estimated for the Risso's dolphin (TL=5.40) and the lowest for the common bottlenose dolphin (TL=4.47). The striped dolphin played the highest top-down control, showing cascading effects up to the 3rd TL. The Risso's dolphin and the sperm whale played similar cascading effects, but weaker than the striped dolphin. Understanding pattern and strengthen of trophic controls played by the Odontocetes within the food web could contribute to identify the basal mechanisms involved in the ecosystem functioning

A possible role of fzd10 delivering exosomes derived from colon cancers cell lines in inducing activation of epithelial–mesenchymal transition in normal colon epithelial cell line

Exosomes belong to the family of extracellular vesicles released by every type of cell both in normal and pathological conditions. Growing interest in studies indicates that extracellular vesicles, in particular, the fraction named exosomes containing lipids, proteins and nucleic acid, represent an efficient way to transfer functional cargoes between cells, thus combining all the other cell–cell interaction mechanisms known so far. Only a few decades ago, the involvement of exosomes in the carcinogenesis in different tissues was discovered, and very recently it was also observed how they carry and modulate the presence of Wnt pathway proteins, involved in the carcinogenesis of gastrointestinal tissues, such as Frizzled 10 protein (FZD10), a membrane receptor for Wnt. Here, we report the in vitro study on the capability of tumor-derived exosomes to induce neoplastic features in normal cells. Exosomes derived from two different colon cancer cell lines, namely the non-metastatic CaCo-2 and the metastatic SW620, were found to deliver, in both cases, FZD10, thus demonstrating the ability to reprogram normal colonic epithelial cell line (HCEC-1CT). Indeed, the acquisition of specific mesenchymal characteristics, such as migration capability and expression of FZD10 and markers of mesenchymal cells, was observed. The exosomes derived from the metastatic cell line, characterized by a level of FZD10 higher than the exosomes extracted from the non-metastatic cells, were also more efficient in stimulating EMT activation. The overall results suggest that FZD10, delivered by circulating tumor-derived exosomes, can play a relevant role in promoting the CRC carcinogenesis and propagation