Characteristics of the patients with IBS in relation to val158met COMT polymorphism based on the symptom diary.

<p>54 IBS subjects (48 women) completed the symptom diary. The val/val genotype was significantly associated with multiple measures clustering towards IBS-diarrhea-like symptoms compared with the rest (val/met+met/met carriers). Statistics: Kruskal-Wallis (all three genotypes compared against each other in column 5, and val/val carriers compared with the other carriers grouped together in column 6).</p><p>*Statistically significant: p<0.05. Borderline statistically significant: p values between 0.05–0.15. ns = non-significant.</p