Clinical characteristics of the colorectal cancer subsets.

<p>Clinical characteristics of the colorectal cancer subsets.</p

Up-regulated signaling pathways in FCCTX and Lynch syndrome tumors.

<p>Up-regulated signaling pathways in FCCTX and Lynch syndrome tumors.</p

qRT-PCR analysis of 5 target genes in the four different colorectal cancer subsets.

<p>Differential expression of <i>MYC, NDUFA9</i>, <i>H2AFZ</i>, <i>AXIN2</i>, and <i>DNA2</i> was done for 12 representative samples (3 from each group) and qRT-PCR ratios were normalized to rRNA18S and median centered.</p

Unsupervised hierarchical clustering based on our 2188-gene signature applied to external data sets.

<p>a) Clustering based on GSE4554 and b) Clustering based on the four largest batches of the TCGA RNAseqv2 data sets. MMR proficient tumors (green), microsatellite-low tumors (blue) and MMR deficient tumors (red) along the x-axis.</p

Additional file 1 of Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium

Additional file 1