P-TREE STRUCTURES AND EVENT HORIZON: EFFICIENT EVENT-SET IMPLEMENTATIONS

maintaining future events in a general purpose discrete event simulation system, and studies the performance of their event set algorithms under the event horizon principle. For comparison reasons, some well-known event set algorithms were also selected and studied; that is, the Dynamic-heap and the P-tree algorithms. To gain insight into the performance of the proposed event set algorithms and allow comparisons with the other selected algorithms, they are tested under a wide variety of conditions in an experimental way. The time needed for the execution of the Hold operation is taken as the measure for estimating the average time complexity of the algorithms. The experimental results show that the BP-tree algorithm and the IBP-tree algorithm behave very well with all the sizes of the event set and their performance is almost independent from the stochastic distributions.

Cloning Template Design of Cellular Neural Networks for Associative Memories

synthesis of 2-D filter structures using Fornasini-Marchesin

Treatment of Tourette's syndrome with finasteride

The marked male predominance of Tourette’s syndrome suggests that androgens may play a key role in the pathophysiology of this disorder. Accordingly, androgen receptor antagonists, such as flutamide, significantly attenuate Tourette’s syndrome symptoms (2), yet their efficacy is hindered by severe side effects. A valid alternative to reduce androgen brain signaling may be afforded by inhibitors of 5-alpha-reductase (5-AR), the main rate-limiting enzyme in androgen metabolism. Thus, we tested the efficacy of finasteride, the prototypical 5-AR inhibitor, in a Tourette’s syndrome patient who was unresponsive to traditional therapy. Finasteride is approved for the treatment of benign prostatic hyperplasia and alopecia; it is psychoactive and produces very limited side effects