Quick recovery and no arthrofibrosis in acute anterior cruciate ligament reconstruction. A prospective trial of early versus delayed reconstruction

Background. Anterior cruciate ligaments tears is one of the most frequent orthopae- dics and sports medicine injuries in the athletically active population and timing of reconstruction represents a debated topic. The aim of the study is to compare range of motion (ROM) recovery and clinical outcomes between patients operated for acute reconstruction (maximum 2 weeks injury-surgery interval) and delayed reconstruction (minimum 3 weeks injury-surgery interval). Methods. A total of 52 patients were prospectively involved in the study. 26 patients underwent acute reconstruction and 26 delayed reconstruction. A standard physical examination with Lachman and Pivot shift test and a passive ROM measurement with a goniometer were performed at each follow-up (2, 4, 8, 12 and 24 weeks postoper- atively). Clinical outcomes were measured at final follow-up using Knee Injury and Osteoarthritis outcome score (KOOS), Tegner Lysholm Score and International Knee Documentation Committe (IKDC 2000) and KT-1000 evaluation. Single-leg hop test and thigh circumference measurement were performed at final follow-up. Results. Both groups showed no statistically significant differences regarding the ROM. Full ROM was achieved 12 weeks after surgery in both groups. The mean IKDC was 98.7 and 95.2; the mean Tegner Lysholm was 100 and 93.8 and the mean KOOS was 99 and 95.5 in the acute group and delayed ACLR group respectively. Conclusions. There were no differences between acute and delayed anterior cruci- ate ligament reconstruction regarding the risk of arthrofibrosis and clinical outcomes. Acute reconstruction can be performed safely with no increased risk of arthrofibrosis

Recommendations for resuming elective hip and knee arthroplasty in the setting of the SARS‑CoV‑2 pandemic: the European Hip Society and European Knee Associates Survey of Members

The COVID-19 pandemic has disrupted the health care system around the entire globe. A consensus is needed about resuming total hip and knee procedures. The European Hip Society (EHS) and the European Knee Association (EKA) formed a panel of experts that have produced a consensus statement on how the safe re-introduction of elective hip and knee arthroplasty should be undertaken. Methods A prospective online survey was done among members of EHS and EKA. The survey consisted of 27 questions. It includes basic information on demographics and details the participant’s agreement with each recommendation. The participant could choose among three options (agree, disagree, abstain). Recommendations focussed on pre-operative, perioperative, and post-operative handling of patients and precautions. Results A total of 681 arthroplasty surgeons participated in the survey, with 479 fully completing the survey. The participants were from 44 countries and 6 continents. Apart from adhering to National and Local Guidelines, the recommendations concerned how to make elective arthroplasty safe for patients and staf. Conclusion The survey has shown good-to-excellent agreement of the participants with regards to the statements made in the recommendations for the safe return to elective arthroplasty following the frst wave of the COVID-19 pandemi

Resuming elective hip and knee arthroplasty after the first phase of the SARS-CoV-2 pandemic: the European Hip Society and European Knee Associates recommendations

The Covid-19 pandemic has disrupted health care systems all over the world. Elective surgical procedures have been postponed and/or cancelled. Consensus is, therefore, required related to the factors that need to be in place before elective surgery, including hip and knee replacement surgery, which is restarted. Entirely new pathways and protocols need to be worked out. Methods A panel of experts from the European Hip Society and European Knee Association have agreed to a consensus statement on how to reintroduce elective arthroplasty surgery safely. The recommendations are based on the best available evidence and have been validated in a separate survey. Results The guidelines are based on five themes: modification and/or reorganisation of hospital wards. Restrictions on orthopaedic wards and in operation suite(s). Additional disinfection of the environment. The role of ultra-clean operation theatres. Personal protective equipment enhancement. Conclusion Apart from the following national and local guidance, protocols need to be put in place in the patient pathway for primary arthroplasty to allow for a safe retur

Matematica per gli anni '90, II

Prosegue il parallelismo tra matematica "astratta" e mondo esterno. Di particolare rilievo in qiuesto volume \ue8 l'introduzione alla teoria dell'informazione, con una riflessione pratica sui contenuti quotidiani dell'informazione e sui modi di reperirla nelle fonti tipiche. Il riferimento viene poi ampliato ad una introduzione pratica (basata su esempi) alla semiotica. Chiude il libro una prima codifica della teoria dei giochi e una analisi delle strategi

Matematica per gli anni '90

Gli elementi chiave di questo volume sono i parallelismi tra teoria geometrica e mondo reale, insistendo a fondo sulla presa di coscienza della percezione geometrica tridimensionale. Le tavole per la costruzione di solidi non usuali servono ad aumentare questa consapevolezza. L'altro tema che riceve una grande attenzione \ue8 la corrispondenza tra problema aritmetico e problema economico reale, giungendo anche a qualche prima propriet\ue0 di ottimizzazione. Il calcolo delle probabilit\ue0 va oltre le strutture elementari presentando qualche esempio elementare di probabilit\ue0 condizionata, con relativi esempi di risoluzione (senza peraltro anticipare ancora il teorema di Bayes)

Matematica per gli anni '90

Il libro \ue8 rivolto a insegnanti e allievi della prima classe della scuola media. La caratteristica \ue8 il paralleliosmo sistematico (e piuttosto spinto) tra il programma di aritmetica e di geometria e i fatti della vita reale della famiglia. In effetti questa \ue8 la parte che \ue8 stata pi\uf9 sia nella scelta dei temi che nella modellizzazione per renderla adeguata al contesto teorico-pratico tradizionale. Inportante \ue8 l'enfasi teorico-pratica data ai primi elementi di statistica descrittiva. Altro schema mentale fondamentale \ue8 il sistema di riferimento del prodotto cartesiano come strumento concettuale oltre il suo aspetto puramente metrico

Modulation of biomarkers in minimal breast carcinoma

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A Selective Metal-Mediated Approach for the Efficient Self-Assembling of Multi-Component Photoactive Systems

We report on the efficient use of different coordinative affin- ities to quantitatively construct a three-component multi- chromophore system containing one free-base porphyrin, one aluminium(III) monopyridylporphyrin, and one ruth- enium(II) tetraphenylporphyrin in a single step. The Al III monopyridylporphyrin plays the pivotal role in directing the correct self-assembly process, and it behaves as the antenna unit for the photoinduced processes of interest. A two-com- ponent system, containing the same free-base porphyrin and one aluminium(III) tetraphenylporphyrin, was prepared for comparative studies. Both systems are remarkably stable in chlorinated solutions. Their photophysical behaviour was studied in detail by stationary and time-resolved emission techniques. In the two-component system, fast and efficient singlet energy transfer from the Al\u2013porphyrin to the free- base porphyrin is observed; in the three-component system, upon excitation of the Al\u2013porphyrin, a fast (minor of 250 ps) electron transfer process from the Ru\u2013porphyrin to the aluminium\u2013porphyrin is observed