Clinical, demographic, and laboratory characteristics of severe vitiligo patients compared to healthy controls.

Clinical, demographic, and laboratory characteristics of severe vitiligo patients compared to healthy controls.</p

Demographics of patients with mild versus severe vitiligo.

Demographics of patients with mild versus severe vitiligo.</p

Youden indexes for severe vitiligo.

BackgroundHematological markers such as eosinophil-to-lymphocyte (ELR), eosinophil-to-neutrophil (ENR), and eosinophil-to-monocyte (EMR) ratios may be used in the assessment of skin diseases. However, the relationship with vitiligo remains unclear.ObjectivesWe investigated ELR, ENR, and EMR in vitiligo patients and the association with severe vitiligo.MethodsThis study included patients of all ages diagnosed with vitiligo between 2005–2020. ELR, EMR, and ENR were calculated from complete blood counts within 30 days of the first recorded vitiligo diagnosis and 12–18 months before the vitiligo diagnosis. We evaluated the associations between ELR, ENR, and EMR and vitiligo.Results9,826 vitiligo patients (8,398 adults and 1,428 children) and 8,951 age and sex-matched controls were included in this study. We found that ELR, EMR, and ENR were higher in children than in adults. Patients with vitiligo had higher ENR and EMR than their matched controls. Patients with severe vitiligo had higher ELR, ENR, and EMR compared to patients with mild vitiligo. Patients with increased ENR and EMR 12–18 months before the vitiligo diagnosis had a higher chance of having severe vitiligo (ENR: OR = 7.40, pConclusionELR, ENR, and EMR may be used in the assessment and prognosis of vitiligo, especially in severe cases.</div

Clinical and demographic characteristics of patients with chronic vitligo, stratified by age group.

Clinical and demographic characteristics of patients with chronic vitligo, stratified by age group.</p

Hematological parameters of mild vitiligo patients compared to healthy controls.

Hematological parameters of mild vitiligo patients compared to healthy controls.</p

Hematologic ratios of patients with chronic vitligo, stratified by age group.

Hematologic ratios of patients with chronic vitligo, stratified by age group.</p

Demographic characteristics of patients with vitiligo, stratified by severity group.

Demographic characteristics of patients with vitiligo, stratified by severity group.</p

Demographics of children vs adults.

BackgroundHematological markers such as eosinophil-to-lymphocyte (ELR), eosinophil-to-neutrophil (ENR), and eosinophil-to-monocyte (EMR) ratios may be used in the assessment of skin diseases. However, the relationship with vitiligo remains unclear.ObjectivesWe investigated ELR, ENR, and EMR in vitiligo patients and the association with severe vitiligo.MethodsThis study included patients of all ages diagnosed with vitiligo between 2005–2020. ELR, EMR, and ENR were calculated from complete blood counts within 30 days of the first recorded vitiligo diagnosis and 12–18 months before the vitiligo diagnosis. We evaluated the associations between ELR, ENR, and EMR and vitiligo.Results9,826 vitiligo patients (8,398 adults and 1,428 children) and 8,951 age and sex-matched controls were included in this study. We found that ELR, EMR, and ENR were higher in children than in adults. Patients with vitiligo had higher ENR and EMR than their matched controls. Patients with severe vitiligo had higher ELR, ENR, and EMR compared to patients with mild vitiligo. Patients with increased ENR and EMR 12–18 months before the vitiligo diagnosis had a higher chance of having severe vitiligo (ENR: OR = 7.40, pConclusionELR, ENR, and EMR may be used in the assessment and prognosis of vitiligo, especially in severe cases.</div

Laboratory characteristics of patients with vitiligo, stratified by severity group.

Laboratory characteristics of patients with vitiligo, stratified by severity group.</p

Regression for severe vitiligo.

BackgroundHematological markers such as eosinophil-to-lymphocyte (ELR), eosinophil-to-neutrophil (ENR), and eosinophil-to-monocyte (EMR) ratios may be used in the assessment of skin diseases. However, the relationship with vitiligo remains unclear.ObjectivesWe investigated ELR, ENR, and EMR in vitiligo patients and the association with severe vitiligo.MethodsThis study included patients of all ages diagnosed with vitiligo between 2005–2020. ELR, EMR, and ENR were calculated from complete blood counts within 30 days of the first recorded vitiligo diagnosis and 12–18 months before the vitiligo diagnosis. We evaluated the associations between ELR, ENR, and EMR and vitiligo.Results9,826 vitiligo patients (8,398 adults and 1,428 children) and 8,951 age and sex-matched controls were included in this study. We found that ELR, EMR, and ENR were higher in children than in adults. Patients with vitiligo had higher ENR and EMR than their matched controls. Patients with severe vitiligo had higher ELR, ENR, and EMR compared to patients with mild vitiligo. Patients with increased ENR and EMR 12–18 months before the vitiligo diagnosis had a higher chance of having severe vitiligo (ENR: OR = 7.40, pConclusionELR, ENR, and EMR may be used in the assessment and prognosis of vitiligo, especially in severe cases.</div