689 research outputs found
Controlling a mesoscopic spin environment by quantum bit manipulation
We present a unified description of cooling and manipulation of a mesoscopic
bath of nuclear spins via coupling to a single quantum system of electronic
spin (quantum bit). We show that a bath cooled by the quantum bit rapidly
saturates. Although the resulting saturated states of the spin bath (``dark
states'') generally have low degrees of polarization and purity, their symmetry
properties make them a valuable resource for the coherent manipulation of
quantum bits. Specifically, we demonstrate that the dark states of nuclear
ensembles can be used to coherently control the system-bath interaction and to
provide a robust, long-lived quantum memory for qubit states.Comment: 4 pages, 3 figure
Bacterial Hsp70 resolves misfolded states and accelerates productive folding of a multi-domain protein
The ATP-dependent Hsp70 chaperones (DnaK in E. coli) mediate protein folding in cooperation with J proteins and nucleotide exchange factors (E. coli DnaJ and GrpE, respectively). The Hsp70 system prevents protein aggregation and increases folding yields. Whether it also enhances the rate of folding remains unclear. Here we show that DnaK/DnaJ/GrpE accelerate the folding of the multi-domain protein firefly luciferase (FLuc) 20-fold over the rate of spontaneous folding measured in the absence of aggregation. Analysis by single-pair FRET and hydrogen/deuterium exchange identified inter-domain misfolding as the cause of slow folding. DnaK binding expands the misfolded region and thereby resolves the kinetically-trapped intermediates, with folding occurring upon GrpE-mediated release. In each round of release DnaK commits a fraction of FLuc to fast folding, circumventing misfolding. We suggest that by resolving misfolding and accelerating productive folding, the bacterial Hsp70 system can maintain proteins in their native states under otherwise denaturing stress conditions. The Hsp70 system prevents protein aggregation and increases folding yields, but it is unknown whether it also enhances the rate of folding. Here the authors combine refolding assays, FRET and hydrogen/deuterium exchange-mass spectrometry measurements to study the folding of firefly luciferase and find that the bacterial Hsp70 actively promotes the folding of this multi-domain protein
High-Order Multipole Radiation from Quantum Hall States in Dirac Materials
We investigate the optical response of strongly disordered quantum Hall
states in two-dimensional Dirac materials and find qualitatively different
effects in the radiation properties of the bulk versus the edge. We show that
the far-field radiation from the edge is characterized by large multipole
moments (> 50) due to the efficient transfer of angular momentum from the
electrons into the scattered light. The maximum multipole transition moment is
a direct measure of the coherence length of the edge states. Accessing these
multipole transitions would provide new tools for optical spectroscopy and
control of quantum Hall edge states. On the other hand, the far-field radiation
from the bulk appears as random dipole emission with spectral properties that
vary with the local disorder potential. We determine the conditions under which
this bulk radiation can be used to image the disorder landscape. Such optical
measurements can probe sub-micron length scales over large areas and provide
complementary information to scanning probe techniques. Spatially resolving
this bulk radiation would serve as a novel probe of the percolation transition
near half-filling.Comment: v2: 8 pages, 4 figure
Topology by dissipation
Topological states of fermionic matter can be induced by means of a suitably
engineered dissipative dynamics. Dissipation then does not occur as a
perturbation, but rather as the main resource for many-body dynamics, providing
a targeted cooling into a topological phase starting from an arbitrary initial
state. We explore the concept of topological order in this setting, developing
and applying a general theoretical framework based on the system density matrix
which replaces the wave function appropriate for the discussion of Hamiltonian
ground-state physics. We identify key analogies and differences to the more
conventional Hamiltonian scenario. Differences mainly arise from the fact that
the properties of the spectrum and of the state of the system are not as
tightly related as in a Hamiltonian context. We provide a symmetry-based
topological classification of bulk steady states and identify the classes that
are achievable by means of quasi-local dissipative processes driving into
superfluid paired states. We also explore the fate of the bulk-edge
correspondence in the dissipative setting, and demonstrate the emergence of
Majorana edge modes. We illustrate our findings in one- and two-dimensional
models that are experimentally realistic in the context of cold atoms.Comment: 61 pages, 8 figure
Voltage-controlled electron-hole interaction in a single quantum dot
The ground state of neutral and negatively charged excitons confined to a
single self-assembled InGaAs quantum dot is probed in a direct absorption
experiment by high resolution laser spectroscopy. We show how the anisotropic
electron-hole exchange interaction depends on the exciton charge and
demonstrate how the interaction can be switched on and off with a small dc
voltage. Furthermore, we report polarization sensitive analysis of the
excitonic interband transition in a single quantum dot as a function of charge
with and without magnetic field.Comment: Conference Proceedings, Physics and Applications of Spin-Related
  Phenomena in Semiconductors, Santa Barbara (CA), 2004. 4 pages, 4 figures;
  content as publishe
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