12 research outputs found
Investigating the impact of a Christian-based life skills training programme: Perceptions of unemployed people
An African perspective on the genetic diversity of Toxoplasma gondii: A systematic review
The study of Toxoplasma gondii genotypes is beneficial for detecting strains linked to increased disease severity and uncovering the processes involved in the transmission and distribution of this zoonotic parasite. A systematic review of literature was conducted to investigate the present status of T. gondii genetic diversity in African countries and among host species on the continent. Data from the results in the included studies were sorted, reviewed and descriptively analysed using tables, graphs and maps. Results indicate that there is a relative amount of genetic diversity with a clear difference in the population structure between geographical regions and the propensity for unique and regional genotypes to be predominant in tropical rainforest biomes, near the equator. From a clinical perspective, connections between specific T. gondii genotypes and disease manifestations were found. Theories are outlined on the dissemination of African T. gondii genotypes to other continents. The overrepresentation of samples from one geographical area and dissimilar genotyping methodologies creates challenges when concluding on the genetic diversity of T. gondii in Africa. The need for uniform genotyping methods with a continent-wide sampling of an extensive host range involving humans, domestic animals and wildlife is emphasized
Results of routine examinations for parasitic infections of humans from laboratory-submitted samples in Gauteng, North West and Mpumalanga Provinces between 2009 and 2010
Very few recent studies have been done in South Africa on the occurrence or prevalence of
parasites in humans. Based on the results of routine examinations for parasitic infections
conducted in the Microbiology Laboratory of Ampath in Pretoria, this study focuses on the
spectrum of parasites diagnosed in samples from humans in Gauteng, North West and
Mpumalanga provinces between 2009 and 2010. Database searches for results of samples in
which parasites were positively identified were conducted using the laboratory’s internal
software system. Data of the positive results were exported and sorted according to date,
specimen type, parasite identified, patient age, gender and geographic locality. Results
showed that a total of 24 different species of parasites were identified in the laboratory over the
two-year period. The overall numbers of parasites identified, according to the data searches,
were 863 and 1061 in 2009 and 2010, respectively. The following parasites were identified:
Entamoeba coli, Entamoeba histolytica, Endolimax nana, Acanthamoeba sp,
Giardia intestinalis, Trichomonas hominis, Trichomonas vaginalis, Chilomastix mesnili,
Blastocystis hominis, Cryptosporidium spp, Cystoisospora belli, Sarcocystis sp,
Enterobius vermicularis, Ascaris lumbricoides, Trichuris trichiura, ancylostomatids (hookworm),
Taenia saginata, Taenia solium, Dipylidium caninum, Inermicapsifer madagascariensis,
Bertiella studeri, Schistosoma haematobium, Echinococcus granulosus and
Cordylobia anthropophaga. In both years, the majority of cases originated from Gauteng
Province followed by North West and Mpumalanga provinces. The data were summarized
descriptively and compared with available published records.Dissertation (MSc)--University of Pretoria, 2013.gm2014Veterinary Tropical Diseasesunrestricte
An African perspective on the genetic diversity of Toxoplasma gondii: A systematic review
A systematic review on available literature on the genotypes of Toxoplasma gondii that have been found in African countrie