Hazard ratios (HR) and 95%CI for alcohol-related disorders (ARD) in offspring in population II (G3) by grandparental (G1) and parental (G2) social classes stratified by gender: The Uppsala Birth Cohort Multigenerational Study (UBCoS Multigen).

<p>Hazard ratios (HR) and 95%CI for alcohol-related disorders (ARD) in offspring in population II (G3) by grandparental (G1) and parental (G2) social classes stratified by gender: The Uppsala Birth Cohort Multigenerational Study (UBCoS Multigen).</p

Associations between parental educational level and ED in daughters, comparing associations across ED subtypes and across birth years.

<p>CI = confidence interval, ED = eating disorder, EDNOS = eating disorder not otherwise specified. All models adjust for all parent SEP variables (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0106475#pone-0106475-t001" target="_blank">Table 1</a>) plus parental age and the index cohort member's birth year. †Analyses comparing ED subtypes exclude those born before 1985 because the three-way division of these subtypes only became possible in 1997 when ICD-10 was introduced. N = 4362 females for anorexia nervosa; N = 1169 for bulimia nervosa; and N = 4607 for EDNOS. ‡Results very similar if restricted to inpatient diagnoses, which were available across all years for all cohort members.</p

Intergenerational profile of study population I and population II: UBCoS Multigen.

<p>Abbreviations: ARD = alcohol-related disorders, G = generation, UBCoS Multigen = the Uppsala Birth Cohort Multigenerational Study. Boxes represent generations under analyses with established biological relations and arrows denote potential pathways between generations. Variables <i>in Italics</i> signify independent (social class) and dependent (ARD) variables measured in corresponding generations.</p

Parental and grandparental predictors of rates of eating disorder hospitalisation among Swedish males born 1975–1998.

<p>*p<0.05, **p<0.01, ***p<0.001 for heterogeneity. ED = eating disorder not-otherwise-specified, CI = confidence interval. Basic education is up to age 16, Secondary education is up to age 18–19. Adjusted analyses adjust for all variables in the column plus the age of the grandparents and parents at the birth of their son, and the birth year of the index cohort member. Note that the birth years are restricted to 1975–1998, as it is for males born in in these years that the distinction between anorexia and non-anorexia ED was always available in the contemporary ICD version.</p><p>Parental and grandparental predictors of rates of eating disorder hospitalisation among Swedish males born 1975–1998.</p

Cohort profile within the population I and II: The Uppsala Birth Cohort Multigenerational Study (UBCoS Multigen).

<p>Cohort profile within the population I and II: The Uppsala Birth Cohort Multigenerational Study (UBCoS Multigen).</p

Incident cases of alcohol-related disorders (ARD) in offspring in population I (G2) and population II (G3) stratified by gender: The Uppsala Birth Cohort Multigenerational Study (UBCoS Multigen).

<p>Incident cases of alcohol-related disorders (ARD) in offspring in population I (G2) and population II (G3) stratified by gender: The Uppsala Birth Cohort Multigenerational Study (UBCoS Multigen).</p

Association between maternal grandparent education and ED in granddaughters, stratifying by whether the grandparent was alive when the granddaughter turned 12 (N = 1,040,165 females).

<p>CI = confidence interval, ED = eating disorder.</p

Association between parent SEP and duration of first ED inpatient hospitalisation, among 5867 Swedish males and females born 1973–1998.

†<p>From linear regression predicting to log-transformed mean duration of hospitalisation, adjusting for the child's birth year, type of disorder and age at admission. Note these analyses use the duration of the first inpatient hospitalization, not excluding individuals who had previously received an outpatient diagnosis: the total number of inpatient cases is therefore higher than the 4177 cases <i>first</i> identified in the inpatient register.</p><p>Association between parent SEP and duration of first ED inpatient hospitalisation, among 5867 Swedish males and females born 1973–1998.</p

Incidence rates of myocardial infarction by socioeconomic position for Swedish men and women in three age groups.

<p>All models were adjusted for birth country and stratified by sex and attained age. Note 1 <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0105279#pone-0105279-g001" target="_blank">Figure 1:</a> The shadowed area indicates a time period for which results cannot be interpreted.</p

Frequencies and incidence rates of myocardial infarction and ischemic stroke by sex, attained age, birth country and socioeconomic position.

1<p>Unadjusted incidence rate per 100,000 person-years.</p>2<p>Age and sex standardized incidence rate per 100,000 person-years using the Swedish population in 2011 as standard population).</p><p>Frequencies and incidence rates of myocardial infarction and ischemic stroke by sex, attained age, birth country and socioeconomic position.</p