8 research outputs found
ΠΠ΅ΡΡΠΎΡΠ°ΡΠΈΡ ΠΏΡΠ°Π²ΠΎΠ³ΠΎ ΠΆΠ΅Π»ΡΠ΄ΠΎΡΠΊΠ° ΠΊΠ°ΠΊ ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠ΅ ΠΈΠΌΠΏΠ»Π°Π½ΡΠ°ΡΠΈΠΈ ΡΠ»Π΅ΠΊΡΡΠΎΠΊΠ°ΡΠ΄ΠΈΠΎΡΡΠΈΠΌΡΠ»ΡΡΠΎΡΠ°
In task present one case of right ventricular perforation by an electrode pacemaker. In case of not complicated perforating of chambers of heart, the is active-waiting tactics of treatment consisting in implantation of an additional electrode without remove the previous is offered.Π ΡΡΠ°ΡΡΠ΅ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½ ΡΠ»ΡΡΠ°ΠΉ ΠΏΠ΅ΡΡΠΎΡΠ°ΡΠΈΠΈ ΠΌΠΈΠΎΠΊΠ°ΡΠ΄Π° ΠΏΡΠ°Π²ΠΎΠ³ΠΎ ΠΆΠ΅Π»ΡΠ΄ΠΎΡΠΊΠ° ΡΠ»Π΅ΠΊΡΡΠΎΠ΄ΠΎΠΌ ΡΠ»Π΅ΠΊΡΡΠΎΠΊΠ°ΡΠ΄ΠΈΠΎΡΡΠΈΠΌΡΠ»ΡΡΠΎΡΠ°. Π ΡΠ»ΡΡΠ°Π΅ Π½Π΅ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½Π½ΠΎΠΉ ΠΏΠ΅ΡΡΠΎΡΠ°ΡΠΈΠΈ ΠΊΠ°ΠΌΠ΅Ρ ΡΠ΅ΡΠ΄ΡΠ° ΠΏΡΠ΅Π΄Π»ΠΎΠΆΠ΅Π½Π° Π°ΠΊΡΠΈΠ²Π½ΠΎ-Π²ΡΠΆΠΈΠ΄Π°ΡΠ΅Π»ΡΠ½Π°Ρ ΡΠ°ΠΊΡΠΈΠΊΠ° Π»Π΅ΡΠ΅Π½ΠΈΡ, Π·Π°ΠΊΠ»ΡΡΠ°ΡΡΠ°ΡΡΡ Π² ΠΈΠΌΠΏΠ»Π°Π½ΡΠ°ΡΠΈΠΈ Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠ»Π΅ΠΊΡΡΠΎΠ΄Π° Π±Π΅Π· ΡΠΊΡΡΡΠ°ΠΊΡΠΈΠΈ ΠΏΡΠ΅Π΄ΡΠ΄ΡΡΠ΅Π³ΠΎ
Pharmacological regulation with antioxidants of hepatocyte cytolysis in acute D-galactosamine-induced intoxication
A rat model of D-galactosamine-induced (0.3 g/kg) liver damage is used to study antioxidant and membrane-stabilizing activity of sodium selenite, vitamin E, and their combination (administered per os, daily, for 3 days before intoxication). It is shown that sodium selenite is 300-fold more effective than vitamin E, while their combination exhibits synergism and potentiation of the antioxidant and membrane-stabilizing activities, underlying inhibition of hepatocyte cytolysis. Β©1998 Plenum Publishing Corporation
Problems and controversial issues in diagnostics of pneumonia in newborns
The literature review on the basis of modern domestic and foreign literature data presents information about pneumonia in newborns. It discusses issues of classification and diagnostic criteria for the disease; summarizes actual information about peculiarities, epidemiology of neonatal pneumonia, etiology and specific risk factors for congenital pneumonia, pneumonia with early and late onset, including nosocomial and ventilator-associated pneumonia, communityacquired pneumonia in newborns. It provides data on frequency of respiratory and general clinical symptoms, results of image diagnostics and laboratory diagnostics of the disease. Β© 2019, Pediatria Ltd.. All rights reserved
Congenital deficiency of surfactant protein c: Literature review and first clinical observations in the russian federation
Surfactant is a complex mixture of phospholipids, neutral lipids and specific surfactant-associated proteins. Genetic diseases associated with gene mutations of surfactant proteins are rare, and treatment options for these children are currently limited. The article presents modern information on congenital deficiency of surfactant protein C, its genetics, pathogenesis, histological patterns, clinical and radiological manifestations in children and adults, outcomes and therapy. It also provides clinical observations of first three pediatric patients in the Russian Federation with this disease, including a rare manifestation in the form of primary pulmonary alveolar proteinosis. Β© 2018, Pediatria Ltd. All rights reserved
DISEASES ASSOCIATED WITH MUTATIONS IN THE FILAMIN A GENE: THE DIFFICULT PATH TO DIAGNOSIS (TWO CLINICAL CASES)
The article presents the first descriptions of observations in the Russian Federation, the difficult path to diagnosis in two young girls with diseases associated with mutations in the filamin A gene, characterized by damage to the central nervous system (periventricular nodular heterotopy), lungs (interstitial emphysematous lesion due to impaired growth), cardiovascular system (open arterial duct, high pulmonary hypertension, insufficiency of heart valves, large vessels). Clinical and anamnestic data, the results of laboratory and instrumental diagnostic methods, including molecular genetic ones, which allowed to identify unique, previously undescribed mutations, the characteristics of the course of the disease, the treatment being carried out, are presented. Β© The Authors
In children with bronchial asthma: Causal, complicated, unspecified, reverse
The review, based on modern literature data and the results of many years of research conducted by the authors, highlights the problem of comorbidity (multimorbidity) in children with bronchial asthma (BA). There is a grouping of concomitant diseases in children with asthma depending on the type of comorbidity (causal, complicated, unspecified, reverse). Based on epidemiological data, observational and cohort studies, systematic reviews and meta-analyses, information on the frequency of BA in children with various comorbid diseases and comorbid diseases in children with BA was summarized. Scientific, theoretical and practical significance of comorbidity in BA, diagnostic and treatment programs in pediatric patients suffering from BA and comorbid diseases are substantiated. Β© 2021, Pediatria Ltd.. All rights reserved
The structure of interstitial lung diseases in children of the first two years of life
For the first time in Russia, the article provides data on interstitial lung diseases structure in children of the first two years of life, based on a series of observations of 68 patients with these rare diseases, as a part of multi-center ambispective study. Interstitial lung diseases in observed children included: Wilson-Mikity syndrome (23,4%), neuroendocrine hyperplasia of infancy (22%), bronchiolitis obliterans with organizing pneumonia (7,4%), primary pulmonary hypoplasia (1,5%), secondary pulmonary hypoplasia with Jeune syndrome (10,3%), secondary pulmonary hypoplasia with Edwards syndrome (2,9%), secondary pulmonary hypoplasia with other associated pathology (omphalocele - 1,5%, non-immune fetal hydrops - 1,5%), subpleural cysts in patients with Down syndrome (5,9%), congenital deficiency of surfactant protein B (1,5%), brain-lung- thyroid syndrome (2,9%), congenital alveolar-capillary dysplasia (1,5%), interstitial lung diseases with systemic diseases (Langerhans cell histiocytosis - 16,2%, Niemann-Pick disease - 1,5%). The article summarizes clinical features, the results of image diagnosis and disease outcomes. Β© 2015, Pediatria Ltd. All rights reserved
The structure of interstitial lung diseases in children of the first two years of life
For the first time in Russia, the article provides data on interstitial lung diseases structure in children of the first two years of life, based on a series of observations of 68 patients with these rare diseases, as a part of multi-center ambispective study. Interstitial lung diseases in observed children included: Wilson-Mikity syndrome (23,4%), neuroendocrine hyperplasia of infancy (22%), bronchiolitis obliterans with organizing pneumonia (7,4%), primary pulmonary hypoplasia (1,5%), secondary pulmonary hypoplasia with Jeune syndrome (10,3%), secondary pulmonary hypoplasia with Edwards syndrome (2,9%), secondary pulmonary hypoplasia with other associated pathology (omphalocele - 1,5%, non-immune fetal hydrops - 1,5%), subpleural cysts in patients with Down syndrome (5,9%), congenital deficiency of surfactant protein B (1,5%), brain-lung- thyroid syndrome (2,9%), congenital alveolar-capillary dysplasia (1,5%), interstitial lung diseases with systemic diseases (Langerhans cell histiocytosis - 16,2%, Niemann-Pick disease - 1,5%). The article summarizes clinical features, the results of image diagnosis and disease outcomes. Β© 2015, Pediatria Ltd. All rights reserved