The coexistence of invasive ductal carcinoma and malignant phyllodes tumor with liposarcomatous and chondrosarcomatous differentiation in the same breast in a post-osteosarcoma case

Malignant phyllodes tumors of the breast are rare biphasic neoplasms, the stromal component of which may show homologous and heterologous sarcomatous elements. Malignant epithelial transformation is rare. It has been reported in a few cases of in situ and infiltrating ductal or lobular carcinoma. Rarely, breast carcinomas and phyllodes tumors may also develop in the same breast independent of each other. To our knowledge, this is the first case of two different types of tumor occurring in the same breast at the same time in a post-osteosarcoma case. (C) 2008 Elsevier GmbH. All rights reserved

Clinical, histopathological and mineralogical analysis findings of an unusual case of pneumoconiosis

A 43-year-old man with a long history of dyspnea which had progressively worsened over the preceding month is presented. He had worked in an antimony mine for 3 years. Radiologically, there were diffuse reticulonodular shadowing opacities in both lung parenchymas. Histopathologic examination of the open-lung biopsy specimen revealed alveolar spaces filled with dust-laden macrophages and amorphous proteinaceous semifluid, the latter being immunoreactive for Human Surfactant Apoprotein A, associated with marked interstitial accumulation of the similar-looking macrophages along the bronchovascular bundles and mild interstitial fibrosis. Silicotic nodules or mixed dust fibrosis were not seen. The patient was diagnosed as silicoproteinosis with unusual histopathological features because he had worked in an antimony mine for only 3 years and had 86% silica in a mineralogical analysis. Pneumoconiosis is a rare lung disease which may be confused with other interstitial lung diseases. Clinical, radiological and unusual histopathologic features of this rare case are presented and discussed with the differential diagnosis, especially of mixed dust pneumoconiosis.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Si{dotless}radi{dotless}şi{dotless} bir pnömokonyozis olgusunun klinik, histopatolojik ve mineralojik analiz Bulgulari{dotless}

A 43-year-old man with a long history of dyspnea which had progressively worsened over the preceding month is presented. He had worked in an antimony mine for 3 years. Radiologically, there were diffuse reticulonodular shadowing opacities in both lung parenchymas. Histopathologic examination of the open-lung biopsy specimen revealed alveolar spaces filled with dust-laden macrophages and amorphous proteinaceous semifluid, the latter being immunoreactive for Human Surfactant Apoprotein A, associated with marked interstitial accumulation of the similar-looking macrophages along the bronchovascular bundles and mild interstitial fibrosis. Silicotic nodules or mixed dust fibrosis were not seen. The patient was diagnosed as silicoproteinosis with unusual histopathological features because he had worked in an antimony mine for only 3 years and had 86% silica in a mineralogical analysis. Pneumoconiosis is a rare lung disease which may be confused with other interstitial lung diseases. Clinical, radiological and unusual histopathologic features of this rare case are presented and discussed with the differential diagnosis, especially of mixed dust pneumoconiosis.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

untitled

A 58-year-old male patient with a mass in the left side of the neck for 3 months was admitted to hospital. Physical examination revealed two masses; a mobile, painless, left jugular mass (lymphadenopathy?) and a parapharyngeal mass behind the left tonsilla palatina. Computed tomography examination of the cervical region and pharynx demonstrated two soft tissue masses. Th e fi rst mass was in the left parapharyngeal region and about 3.5x3x3 cm in dimensions. Th is mass was well-circumscribed and showed heterogeneous contrast uptake. Th e second one was 4.5x2.5x2 cm, sharply delineated and homogeneous. It was partly embedded in the caudal region of the left parotid gland. Th e initial clinical diagnosis was a probable metastatic malignant tumor. Fine needle aspiration was done for th