Epidemiology of pancreatic cancer

© The Author(s) 2016. Cancer of the pancreas remains one of the deadliest cancer types. Based on the GLOBOCAN 2012 estimates, pancreatic cancer causes more than 331000 deaths per year, ranking as the seventh leading cause of cancer death in both sexes together. Globally, about 338000 people had pancreatic cancer in 2012, making it the 11th most common cancer. The highest incidence and mortality rates of pancreatic cancer are found in developed countries. Trends for pancreatic cancer incidence and mortality varied considerably in the world. A known cause of pancreatic cancer is tobacco smoking. This risk factor is likely to explain some of the international variations and gender differences. The overall five-year survival rate is about 6% (ranges from 2% to 9%), but this vary very small between developed and developing countries. To date, the causes of pancreatic cancer are still insufficiently known, although certain risk factors have been identified, such as smoking, obesity, genetics, diabetes, diet, inactivity. There are no current screening recommendations for pancreatic cancer, so primary prevention is of utmost importance. A better understanding of the etiology and identifying the risk factors is essential for the primary prevention of this disease

Familial aggregation of bladder cancer

Background. Except for smoking and certain occupational exposures, the etiology of bladder cancer is largely unknown. Several case reports have described familial aggregation of transitional cell carcinoma of the bladder. Although the majority of patients with bladder cancer do not have family history of transitional cell carcinoma of the urinary tract, the study of familial transitional cell carcinoma may lead to the knowledge on the pathogenesis of this disease. The purpose of this study was to describe three cases of urinary bladder cancer in a single three-member family, i.e. in two generations (mother and son) and a family member related by marriage (the patient's wife). Case report. Three cases of urinary bladder cancer occurred in a three-member family within the interval of 5 years. The following common characteristics were detected in our patients: old age (over 60), working as farmers for more than 50 years, negative personal medical history on relevant health disorders, place of birth - village, place of residence - village, the same water supply, similar nutrition, positive family history on urinary bladder cancer or other malignant tumors, the first sign of illness was macroscopic hematuria in all the patients and the same pathohistological type of cancer - carcinoma papillare transitiocellulare. Conclusion. The stated common characteristics in our cases indicate, above all, the impact of exposure to external surrounding factors on the occurrence of urinary bladder cancer

Indicators of Entrepreneurial Behavior and Attitudes for Entrepreneurs of Slovenia and Croatia, in 2018/2019

Abstract. Following the theoretical presentation of entrepreneurship, that is, the determinants that determine the success of entrepreneurial ventures extracted from various scientific studies and research, the paper defines through research the indicators of entrepreneurial behavior and attitudes using the Global Entrepreneurship Monitor 2018/2019 Global Report database. Using the methods of comparison, induction and deduction, an analysis of indicators of Entrepreneurial Behavior and Attitudes for Slovenia and Croatia was conducted. 

LEADERSHIP AND MANAGEMENT AND ITS ROLE IN STRATEGIC CHANGE

Leadership and management, as two important processes in organizations, have a significant impact on all interactions and other processes that occur within an organization. The process of strategic change, important for the survival of organizations in turbulent times, is also conditioned by the roles of managers and leaders and their coordination of resources, vision, and the like.The aim of the paper is to demonstrate the influence of managers and leaders on strategic change (strategy implementation), through secondary and primary research.

Critical Success Factors in IT Project Management. Case study on IT Banking Front-end IT System Project in Serbia

The success of project management in organizations depends on the context, that is, on type of organization, type of projects they implement, the environment and the conditions for the realization of projects. What matters to the textual issues of project success is due to a number of factors - type of project, importance for organization, resources, and the like. Insufficient number of organizations successfully managed to implement project manager procedures, while others met with a large number of problems, the resistance of employees first of all, ignorance, lack of resources, bad time management and other issues. Organizations must have an incremental approach to the development and implementation of their project management methodologies, especially when it comes to implementing information technology project, that involve a great deal of human-work, innovation and usually cost a lot, development takes a long time, they are based on the knowledge of new technologies, and their success depends on the people who develop them, and those who will use those IT products and services. This is a great challenge for management in terms of use of information technology, budget and planning, involvement of the project team and establishment of support from the environment. Many IT projects are not implemented successfully because of poor application of project management procedures, lack of stakeholder support, absence of project sponsor etc.

K-12 MODERN SCHOOLS IN SERBIA: EXPLORATORY RESEARCH REGARDING TEACHERS GENUINE KNOWLEDGE AND PERCEPTION OF AI-BASED OPPORTUNITIES AND CHALLENGES IN EDUCATION

LINK Educational Alliance (LEA is an educational group based in the Republic of Serbia which involves privately owned providers of formal and informal education, the format for the development of Educational Technologies services and Business support for their business. The exploratory research was conducted among K-12 teachers among a total population of 152 and a sample of 77 respondents (50.66%) to provide information about the perception of the teachers towards implementation of the Artificial intelligence-based solutions and the opportunities and challenges that artificial intelligence (AI) will bring into their daily activities, as well as their genuine knowledge about AI. For data analysis, we used SmartPLs Software version 3.0, making inferential and variable association analyses. The teaching process, based on the opinion of  K-12 teachers regarding activities that might be automatised through AI implementation in the educational process, supported by their level of awareness and knowledge about AI. For example, AI offers opportunities to automate specific strategies and activities, which would achieve better organisation of teachers' working time and productivity and increase the share of time that teachers spend "directly interacting with students" is the central hypothesis whose validity is tested. The aim of this study is to provide adequate model for testing AI attitudes in K-12 level of education in Republic of Serbia, among teachers in elementary and secondary schools.

MARKETING MIX STRATEGY DETERMINANTS AND SOCIAL MEDIA IN VETERINARY-BASED BUSINESS: EXPERIENCE FROM SERBIA

The paper is dedicated to testing the entrepreneurial idea of founding a service micro company in the field of veterinary medicine - Animal Care. The starting point is the theoretical aspect of marketing mix services observed through the prism of a specific company in the field of agribusiness. For the needs of the research, secondary sources were used and a survey was conducted which gave the results of the influence of the elements of marketing mix services on marketing communication towards the users of the company Animal Care. It was determined that the effects of promotion, especially in the field of digital marketing, directly affect the increase in sales of products and services, and thus the satisfaction of consumers & users in veterinary services. The results of the research provided answers to research questions and helped the entrepreneur to understand that selected elements of the marketing mix help in the promotion of products and services of Animal Care companies. Respondents showed interest in using the services of the Animal Care company with the help of the Animal Care android application and website as a selected distribution channel, but also for the promotion of new services and offers of the company

MARKETING MIX STRATEGY DETERMINANTS AND SOCIAL MEDIA IN VETERINARY-BASED BUSINESS: EXPERIENCE FROM SERBIA

The paper is dedicated to testing the entrepreneurial idea of founding a service micro company in the field of veterinary medicine - Animal Care. The starting point is the theoretical aspect of marketing mix services observed through the prism of a specific company in the field of agribusiness. For the needs of the research, secondary sources were used and a survey was conducted which gave the results of the influence of the elements of marketing mix services on marketing communication towards the users of the company Animal Care. It was determined that the effects of promotion, especially in the field of digital marketing, directly affect the increase in sales of products and services, and thus the satisfaction of consumers & users in veterinary services. The results of the research provided answers to research questions and helped the entrepreneur to understand that selected elements of the marketing mix help in the promotion of products and services of Animal Care companies. Respondents showed interest in using the services of the Animal Care company with the help of the Animal Care android application and website as a selected distribution channel, but also for the promotion of new services and offers of the company

Tuberculosis outbreak in a grammar school, Serbia, 2016

Serbia has a low incidence of tuberculosis (TB), with a decreasing trend in the last decade. The purpose of this manuscript is to describe an outbreak of TB infection that occurred in 2016 among students of a grammar school in Novi Pazar. February and November 2016. A 17-year-old girl, third-grade student of a grammar school (the index case), was diagnosed with smear-positive tuberculosis. Contact investigation was conducted, including chest X-ray examinations of over 1100 persons. After the index case was detected, a total of 16 (10 pulmonary and 6 extrapulmonary) tuberculosis patients were newly diagnosed during 2016. Among 11 culture positive cases, MIRU-VNTR method revealed that all Mycobacterium tuberculosis isolates were identical. Diagnostic delay contributed to the transmission of infection

SOCIALY RESPONSIBLE MARKETING - YESTERDAY AND TODAY

Several factors direct the companies to apply a higher level of corporate social responsibility: the increasing expectations of customers, changes in expectations of employees, laws and government pressure, investor interest in the social criteria and changes in supply practicesThe basic principles of socially responsible marketing as an ethical business, respect for ecological principles and respect for the legislation. Organizations must ensure that all employees know and observe the relevant laws.Companies must adopt and make available to the written rules of ethics, to develop tradition of ethical conduct in the company and impose a responsibility to his men to follow ethical and legal guidelines.By adopting these or similar principles, companies can create opportunities to reduce current and future costs, strengthen competitiveness and market position and achieving greater profits.In contemporary business, more ecological component is present in the execution of business activities as an important prerequisite for improving competitive advantage and company image. Awareness of the issue of environmental protection in companies has evolved primarily as a result of the influence of customers and various non-governmental and non-profit organizations on marketing orientation of companies, and the requirements for the development of products and services that meet environmental standards and consumer needs.