Catalytic Annulation of Diethyl Methylenecyclopropane-1,1-dicarboxylate with 1,1-Dicyanoalkenes

The catalytic annulation of methylenecyclopropane <b>1</b> with 1,1-dicyanoalkenes <b>2</b> using a Mg–Sn catalytic system was developed. Selective formation of cyclopentylidenemalonates <b>3</b> and spiro­[2,3]­hexane-1,1-dicarboxylates <b>4</b> was accomplished via the choice of a proper solvent and an effective catalytic system

Catalytic Annulation of Diethyl Methylenecyclopropane-1,1-dicarboxylate with 1,1-Dicyanoalkenes

The catalytic annulation of methylenecyclopropane <b>1</b> with 1,1-dicyanoalkenes <b>2</b> using a Mg–Sn catalytic system was developed. Selective formation of cyclopentylidenemalonates <b>3</b> and spiro­[2,3]­hexane-1,1-dicarboxylates <b>4</b> was accomplished via the choice of a proper solvent and an effective catalytic system

Catalytic Cycloaddition of 2‑Methyleneaziridines with 1,1-Dicyanoalkenes

2-Methyleneaziridine are a good substrate for the catalytic synthesis of cyclopentylidenamines via a [3 + 2] cycloaddition of 1,1-dicyanoalkenes using Bu₂SnI₂ as an effective catalyst. A C-attack from 2-methyleneaziridine yielded the desired products

Catalytic [3 + 2] Cycloaddition through Ring Cleavage of Simple Cyclopropanes with Isocyanates

The catalytic synthesis of γ-butyrolactams was established via [3 + 2]-cycloaddition of cyclopropanes with isocyanates. An organotin iodide ate complex, MgBr⁺[Bu₂SnBrI₂]⁻, was employed as an effective catalyst. Simple cyclopropanes that lack aryl or vinyl substituents were useful precursors. Even acyl cyclopropanes were applicable. The hybrid characteristics of a tin complex, acidic MgBr⁺ with nucleophilic tin iodide, was responsible for the catalytic reaction

Transition-Metal-Free Reductive Coupling of 1,3-Butadienes with Aldehydes Catalyzed by Dibutyliodotin Hydride

In this study, the Bu₂SnIH-catalyzed direct coupling of 1,3-dienes with aldehydes was developed. This reaction could be suitable for coupling without the use of transition-metal catalysts. Many types of aldehydes were applied to this reaction. The addition of MeOH promoted the catalytic cycle