4 research outputs found

    Exploring leadership communication in the United Arab Emirates: Issues of culture and gender

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    This study aims to identify what makes a successful leader in the UAE within the paradigms of leadership styles and leadership communication. In order to do this, we explore, and potentially challenge, a number of the existing leadership stereotypes that are germane to the region, along with the stereotypical discourse strategies that have been associated with the ways in which men and women enact leadership. We wanted to find out if Emirati nationals would prefer the type of discursive leadership that has been associated with women leaders, that is transformational leadership and collaborative communication, or if they would prefer the discursive leadership that has been stereotypically associated with men in equivalent positions, that is laissez-faire, transactional or paternalisticleadership styles, together with the use of a direct and competitive style of communication. Our findings show that a Western understanding of leadership may be too strictly delineated to account for leadership styles in the Gulf, and also that leaders in the region may effectively draw on a combined set of communication strategies that have been stereotypically attributed elsewhere to male and female leaders

    The increasing mismatch between Arab gender-gaps in education and work participation

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    Purpose of the study: To examine (1) the impact of improvement in Arab women education on their employment during the period 1970 to 2005 & (2) the moderating effect of the sociopolitical environment on this relationship.Peer Reviewe

    Design, Synthesis and In-Vitro Biological Evaluation of Antofine and Tylophorine Prodrugs as Hypoxia-Targeted Anticancer Agents

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    Phenanthroindolizidines, such as antofine and tylophorine, are a family of natural alkaloids isolated from different species of Asclepiadaceas. They are characterized by interesting biological activities, such as pronounced cytotoxicity against different human cancerous cell lines, including multidrug-resistant examples. Nonetheless, these derivatives are associated with severe neurotoxicity and loss of in vivo activity due to the highly lipophilic nature of the alkaloids. Here, we describe the development of highly polar prodrugs of antofine and tylophorine as hypoxia-targeted prodrugs. The developed quaternary ammonium salts of phenanthroindolizidines showed high chemical and metabolic stability and are predicted to have no penetration through the blood–brain barrier. The designed prodrugs displayed decreased cytotoxicity when tested under normoxic conditions. However, their cytotoxic activity considerably increased when tested under hypoxic conditions
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